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  1. Breast cancer infrequently metastasizes to the sternum as solitary metastasis. We experienced successful treatment with proton beam therapy for a case of sternal metastasis of breast cancer. This case demonstr...

    Authors: Yojiro Ishikawa, Motohisa Suzuki, Hisashi Yamaguchi, Ichiro Seto, Masanori Machida, Yoshiaki Takagawa, Keiichi Jingu, Yasuyuki Kikuchi and Masao Murakami
    Citation: Journal of Medical Case Reports 2022 16:111
  2. Oxaliplatin-based chemotherapy represents a standard of care in the treatment of metastatic colorectal cancer. We report a rare case of fulminant oxaliplatin-induced thrombotic microangiopathy, clinically sugg...

    Authors: Rhea Saad, Audra Hannun, Sally Temraz, Antoine Finianos and Rony M. Zeenny
    Citation: Journal of Medical Case Reports 2022 16:110
  3. Buschke–Löwenstein tumor is a giant condyloma acuminata infection that is characterized by degeneration, invasion, and recurrence. It is associated with human papilloma virus infection. It develops around the ...

    Authors: Mathurin Kowo, Jude-Marcel Nzoume Nsope Mengang, Sylvain Raoul Simeni Njonnou, Emmanuel Armand Kouotou, Paul Jean Adrien Atangana and Firmin Ankouane Andoulo
    Citation: Journal of Medical Case Reports 2022 16:116
  4. Breast carcinoma is a common tumor in women, but it rarely metastasizes to the oral region. Furthermore, metastases to the oral region occur mainly to the maxillary and mandibular bone and rarely to soft tissue.

    Authors: Ryo Miyazaki, Natsuko Kimoto, Satsuki Okamoto, Asami Tsuji, Yusuke Nishigushi, Tomoya Miyahara, Nozomu Takahashi and Tetsuji Omata
    Citation: Journal of Medical Case Reports 2022 16:108
  5. Reduced consciousness has a wide variety of possible causes, not infrequently being toxic in nature. An intoxication might be obvious, but in this paper an unexpected case with a tricyclic antidepressant is pr...

    Authors: Tijs van de Wint, Aurelia H. M. de Vries Schultink, Arend Jan Meinders, Ankie Harmsze and Peter Bruins
    Citation: Journal of Medical Case Reports 2022 16:112
  6. Neurologic impediments occur in only 0.1% of Mycoplasma pneumoniae infections. Although direct intracerebral infection can occur in these patients, autoimmune-mediated reactions secondary to molecular mimicry are...

    Authors: Alvin Oliver Payus, Clarita Clarence, Tiong Nee and Wan Nur Nafisah Wan Yahya
    Citation: Journal of Medical Case Reports 2022 16:105
  7. Pancoast tumors represent a unique subset of lung cancers wherein a primary neoplasm arises in the lung’s apex and invades the surrounding soft tissues. One of the main challenges in the diagnosis and treatmen...

    Authors: Safia Mohamud, Mosunmola Oyawusi, Roger L. Weir, Etuajie O. Halbert, Richard M. Millis, Teddy Gebremedhin and Ozra Dehkordi
    Citation: Journal of Medical Case Reports 2022 16:109
  8. Congenital diaphragmatic hernia affects 1 in every 2000–5000 live births. The mediastinum shifts to the opposite side, the lungs are hypoplastic, and the arterioles are abnormal, resulting in pulmonary hyperte...

    Authors: Marjan Tariverdi, Zahra Ghaeini Hesarooeyeh, Elham Khalili, Saeedeh Majidi and Maria Rezazadeh
    Citation: Journal of Medical Case Reports 2022 16:104
  9. Glucose-6-phosphate dehydrogenase deficiency is a rarely recognized predisposing factor for rhabdomyolysis. Rhabdomyolysis with coronavirus disease 2019 has been increasingly seen during the pandemic. We repor...

    Authors: Regina Yu, Chien-Rong Chen, Darci Evans, Xin Qing, Moran Gotesman, Gangadarshni Chandramohan, Thomas Kallay, Henry J. Lin and Tiffany P. Pedigo
    Citation: Journal of Medical Case Reports 2022 16:106
  10. The differential diagnosis of abdominal pain in pregnant women is broad. Liver diseases as the origin of abdominal pain in pregnancy are rare, and severe forms occur in less than 0.1% of pregnancies. Some diso...

    Authors: Claudia Meloni, Cornelia Schreiber, Jan-Dirk Studt, Simone Kamm, Manuela Di Chiara and Thomas Herren
    Citation: Journal of Medical Case Reports 2022 16:103
  11. Noma is a rare disease that occurs mainly in malnourished patients in developing countries. Noma starts as facial swelling and gingival necrosis that eventually necrotizes underlying tissues including the jaw ...

    Authors: Jiho Park, Sanghun Kim, Seung-Woo Shin, Chuhl Joo Lyu and Dongwook Kim
    Citation: Journal of Medical Case Reports 2022 16:97
  12. The abscopal effect is a phenomenon in which a tumor located far from irradiated lesions regresses. We have experienced a case in which both intracranial and extracranial lesions showed an abscopal effect afte...

    Authors: Yojiro Ishikawa, Rei Umezawa, Takaya Yamamoto, Noriyoshi Takahashi, Kazuya Takeda, Yu Suzuki and Keiichi Jingu
    Citation: Journal of Medical Case Reports 2022 16:94
  13. Transverse myelitis is a rare neurological disorder of the spinal cord, caused by inflammation and damage of the myelin sheath of the neurons of the spinal cord across one or more spinal segments. This causes ...

    Authors: Chukwuebuka P. Onyekere and Chinonso N. Igwesi-Chidobe
    Citation: Journal of Medical Case Reports 2022 16:93
  14. Atypical hemolytic uremic syndrome, also called the nondiarrheal form of hemolytic uremic syndrome, is a rare disease characterized by the triad of thrombocytopenia, Coomb’s test-negative microangiopathic hemo...

    Authors: Xin Wei, Juan Li, Xiaojiang Zhan, Luxia Tu, Haowen Huang and Ying Wang
    Citation: Journal of Medical Case Reports 2022 16:101
  15. Scedosporium apiospermum, an opportunistic and filamentous fungus, is a rarely seen ocular entity that is difficult to identify and heal. We report a challenging case of S. apiospermium keratitis and discuss the ...

    Authors: Umut Karaca
    Citation: Journal of Medical Case Reports 2022 16:91
  16. The current coronavirus disease pandemic has brought recognition of multisystem inflammatory syndrome in adults as a de novo entity, temporally associated with severe acute respiratory syndrome coronavirus 2 vira...

    Authors: Fardad Behzadi, Nicolas A. Ulloa and Mauricio Danckers
    Citation: Journal of Medical Case Reports 2022 16:102
  17. To date, the gold-standard treatment for sternoclavicular septic arthritis has been surgery due to the high failure and complication rates of medical treatment. In particular, presentation of Fusobacterium sterno...

    Authors: SangMin Kim, Ruhi Kanwar and M. Blair Marshall
    Citation: Journal of Medical Case Reports 2022 16:90
  18. Of the many types of laser cyclophotocoagulation procedures, micropulse cyclophotocoagulation diode is praised as a noninvasive, safe, and effective procedure with few complications. In this case report, we de...

    Authors: Gaëtane Ghion, Alexandra Singh and Sayeh Pourjavan
    Citation: Journal of Medical Case Reports 2022 16:89
  19. Coronavirus disease 2019 has been associated with adverse pregnancy outcomes, including preeclampsia. Coronavirus disease 2019 and preeclampsia have overlapping clinical features and are therefore challenging ...

    Authors: Pradip Kalsar, Shreya Datta, Arbabasu Kalsar and Andrew Marvin Kanyike
    Citation: Journal of Medical Case Reports 2022 16:100
  20. Hereditary hemorrhagic telangiectasia is an autosomal dominant condition with an estimated prevalence of 1 in 5000. It is characterized by the presence of abnormalities of vascular structures, and may affect m...

    Authors: L. J. Walsh, C. Collins, H. Ibrahim, D. M. Kerins, A. P. Brady and T. M. O Connor
    Citation: Journal of Medical Case Reports 2022 16:99
  21. Subcutaneous low molecular weight heparin is a commonly used anticoagulant. Catastrophic hemorrhage is a known adverse outcome associated with anticoagulant use. Of all potential bleeding sites, hemorrhage int...

    Authors: Yuxuan Zhou and Kingsley Logan
    Citation: Journal of Medical Case Reports 2022 16:87
  22. Calcinosis cutis is a rare condition, characterized by an accumulation of calcium salts in the skin and subcutaneous tissue. There are several types of this condition, including dystrophic, metastatic, idiopat...

    Authors: Eman Ahmed Alghaith, Ghada Abdullah AlQahtani and Jamal Ahmed Omer
    Citation: Journal of Medical Case Reports 2022 16:86
  23. ACAT-related enzyme 2 required for viability 1 (ARV1) encodes a transmembrane lipid transporter of the endoplasmic reticulum, which is presented in all eukaryotes and in plants. Deficiency of ARV1 is clinically p...

    Authors: Anton Karabinos, Michaela Hyblova, Miroslava Eckertova, Erika Tomkova, Drahomira Schwartzova, Nikoleta Luckanicova, Gabriela Magyarova and Gabriel Minarik
    Citation: Journal of Medical Case Reports 2022 16:98
  24. Psychological stress has been reported to cause hyperthermia. Persistent excessive hyperthermia can, in turn, cause hypercytokinemia and organ damage. We report a case of postoperative severe hyperthermia lead...

    Authors: Keiichi Koizumi, Fuminori Numano, Tomoko Tandou, Ken Takada, Minako Hoshiai and Noboru Oyachi
    Citation: Journal of Medical Case Reports 2022 16:84
  25. Paragangliomas are rare vascular neuroendocrine tumors that develop in the extra-adrenal paraganglion tissue. They occur most commonly at the carotid bifurcation, where they are known as carotid body tumors. M...

    Authors: José M. López-Arcas, César M. Colmenero, Roberto Martínez, Fátima Martín-Hernán, Beatriz Ruiz-Sánchez and Juan Manuel Aragoneses
    Citation: Journal of Medical Case Reports 2022 16:92
  26. Sweet syndrome is a rare cause of acute fever and painful erythematous skin plaques. Erythema nodosum is acute or chronic tender erythematous skin nodules of bilateral shins. The concurrent presence of both de...

    Authors: Chamila Mettananda, Hansika Peiris and Ahamed Uwyse
    Citation: Journal of Medical Case Reports 2022 16:82
  27. Mononeuritis multiplex is a rare autoimmune peripheral neuropathy that typically presents in the context of vasculitis, diabetes, infection, or as a paraneoplastic syndrome. Adverse immune-related neurological...

    Authors: Safa Abdelhakim, Jonah D. Klapholz, Bhaskar Roy, Sarah A. Weiss, Declan McGuone and Zachary A. Corbin
    Citation: Journal of Medical Case Reports 2022 16:81
  28. Lipoprotein glomerulopathy is a rare and newly recognized glomerular disease that can lead to kidney failure. Its pathological features include the presence of lipoprotein embolus in the loop cavity of glomeru...

    Authors: Runxiu Wang, Chengbo Zhao, Wen Chen, Zhiping Liu and Fuhua Xie
    Citation: Journal of Medical Case Reports 2022 16:78
  29. Coronavirus disease 2019 has been associated with a plethora of different manifestations of systems affected (including pulmonary, gastrointestinal, and thrombotic disease) and time to presentation of complica...

    Authors: Romesh Tirimanna, James Myerson, Michael Okorie and Eleanor Dorman
    Citation: Journal of Medical Case Reports 2022 16:88
  30. Crimean–Congo hemorrhagic fever is a severe vector-borne viral hemorrhagic fever with considerable mortality in humans. This disease is endemic in Afghanistan, and its incidence rate has rapidly increased in r...

    Authors: Shohra Qaderi, Hossein Hatami, Ahmad Murad Omid and Jalal Sayad
    Citation: Journal of Medical Case Reports 2022 16:76
  31. Mycobacterium malmoense is a species of slow-growing nontuberculous mycobacteria. It causes mostly pulmonary infections or lymphadenitis in children, but is increasingly encountered in isolated tenosynovitis in a...

    Authors: Alex Boudon, Onya Opota and Diana Dan
    Citation: Journal of Medical Case Reports 2022 16:75
  32. Mild encephalitis/encephalopathy with reversible splenial lesion is a clinical-radiological entity found to occur in the setting of an acute systemic inflammatory state with isolated lesions of the splenium of...

    Authors: Nafee T. Talukder, Ashlea Feezel and Jeremy E. Lankford
    Citation: Journal of Medical Case Reports 2022 16:74
  33. Splenosis is the heterotopic autotransplantation of splenic tissue after severe splenic trauma and/or splenectomy. The epidemiology is elusive, but splenosis is frequently misdiagnosed as malignant tumors of g...

    Authors: Bandik Föh, Malte Maria Sieren, Marcus Both, Marcus Seeger and Rainer Günther
    Citation: Journal of Medical Case Reports 2022 16:73
  34. Aggressive angiomyxoma of the vulva is a benign, slow-growing tumor originating from myxoid cells of connective tissue. The tumor is known for multiple local recurrences with a low tendency to metastasize. Onl...

    Authors: Lajya Devi Goyal, Priyanka Garg, Rama Badyal and Shivali Bhalla
    Citation: Journal of Medical Case Reports 2022 16:71
  35. Paroxysmal hypertension can be associated with failure of the carotid artery baroreceptors due to past exposure to radiation treatment. This report describes a patient whose repeated paroxysmal hypertensive ep...

    Authors: Itzhak Brook, Ezra Cohen and Andrew Stemer
    Citation: Journal of Medical Case Reports 2022 16:70
  36. Mucoepidermoid carcinoma is the most common malignant neoplasm arising from the salivary glands (Ali et al. in J Ayub Med Coll Abbottabad 20(2): 141-2, 2008, Xi et al. in World J Surg Oncol 10: 232, 2012). When a...

    Authors: Simran Mashiana and Ernesto Martinez Duarte
    Citation: Journal of Medical Case Reports 2022 16:69
  37. Pyruvate kinase deficiency is an exceptionally rare autosomal recessive Mendelian disorder caused by bi-allelic pathogenic variants in the PKLR gene. It is mainly characterized by chronic nonspherocytic hemolytic...

    Authors: Atta Ur Rehman, Abdur Rashid, Zubair Hussain and Khadim Shah
    Citation: Journal of Medical Case Reports 2022 16:66
  38. The coronavirus disease 2019 pandemic has resulted in a growing population of individuals who experience a wide range of persistent symptoms referred to as “long COVID.” Symptoms include neurocognitive impairm...

    Authors: Aisha M. Bhaiyat, Efrat Sasson, Zemer Wang, Sherif Khairy, Mouzayan Ginzarly, Umair Qureshi, Moin Fikree and Shai Efrati
    Citation: Journal of Medical Case Reports 2022 16:80
  39. A bucket-handle cervical tear, a laceration of the anterior or the posterior lip of the cervix so that it hangs like the handle of a bucket, is the rarest type of cervical laceration. Our case represents such ...

    Authors: Abraham Fessehaye, Mariamawit Asfaw, Hika Hailu Kitila and Wondimu Gudu
    Citation: Journal of Medical Case Reports 2022 16:79
  40. Human immunodeficiency virus-1-associated neurocognitive disorder is a known complication in individuals treated with antiretroviral therapy. Cerebrospinal fluid escape, which is defined as discordant higher c...

    Authors: Didi Bang, Jannik Fonager and Isik Somuncu Johansen
    Citation: Journal of Medical Case Reports 2022 16:62
  41. Radical esophagectomy for esophageal squamous cell carcinoma has improved survival, but the rate of recurrence is high. Patients of recurrent esophageal squamous cell carcinoma after failure of chemotherapy ha...

    Authors: Yojiro Ishikawa, Motohisa Suzuki, Hisashi Yamaguchi, Ichiro Seto, Masanori Machida, Yoshiaki Takagawa, Keiichi Jingu, Yasuyuki Kikuchi and Masao Murakami
    Citation: Journal of Medical Case Reports 2022 16:68
  42. Nivolumab is an immune checkpoint inhibitor that blocks inhibitors of T-cell activation and blunts antitumor immunity and is used in the treatment of various cancers. However, immune checkpoint inhibitors have...

    Authors: Yumi Saishu, Takuya Yoshida, Yusuke Seino and Takeshi Nomura
    Citation: Journal of Medical Case Reports 2022 16:61
  43. Arthrogryposis, renal dysfunction, and cholestasis syndrome (ARCS) is a rare autosomal recessive disorder caused by mutations in VPS33B (ARCS1) and VIPAS39 (ARCS2). As per literature, most patients with ARCS died...

    Authors: Yoshinori Satomura, Kazuhiko Bessho, Nobutoshi Nawa, Hidehito Kondo, Shogo Ito, Takao Togawa, Masanao Yano, Yuki Yamano, Taisuke Inoue, Miho Fukui, Shinsuke Onuma, Tomoya Fukuoka, Kie Yasuda, Takeshi Kimura, Makiko Tachibana, Taichi Kitaoka…
    Citation: Journal of Medical Case Reports 2022 16:60

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