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  1. Content type: Case report

    Giant cell tumor is known to be a benign neoplasm that arises most commonly in the long bones, while cases in the spine are rare. Recently, denosumab, a monoclonal antibody that inhibits receptor activator of ...

    Authors: Hideyuki Kinoshita, Sumihisa Orita, Tsukasa Yonemoto, Takeshi Ishii, Shintaro Iwata, Hiroto Kamoda, Toshinori Tsukanishi, Kazuhide Inage, Koki Abe, Masahiro Inoue, Masaki Norimoto, Tomotaka Umimura, Kazuki Fujimoto, Yasuhiro Shiga, Hirohito Kanamoto, Takeo Furuya…

    Citation: Journal of Medical Case Reports 2019 13:116

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  2. Content type: Case report

    Oral focal mucinosis, the oral counterpart of cutaneous focal mucinosis, is a rare disease. As it has no characteristic clinical or radiological features, diagnosis is established by histopathological and immu...

    Authors: Yusuke Higuchi, Fumihiko Tsushima, Kanako Sumikura, Yuriko Sato, Hiroyuki Harada, Kou Kayamori and Tohru Ikeda

    Citation: Journal of Medical Case Reports 2019 13:108

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  3. Content type: Case report

    Metastatic tumors in the orbit, especially from gastric cancer, are rare. We present a rare case of extraocular muscle metastasis from gastric cancer and raise consideration of metastasis to extraocular muscle...

    Authors: Sakiko Goto, Hiroaki Takeda, Yuriko Sasahara, Imi Takanashi and Hidetoshi Yamashita

    Citation: Journal of Medical Case Reports 2019 13:107

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  4. Content type: Case report

    Congestive heart failure is rarely observed in patients with acromegaly. Excessive growth hormone secretion and elevation of insulin-like growth factor 1 contribute to pathological changes in myocyte growth an...

    Authors: Jun yi Wang, Yong mei Hu, Jian xiong Liu and Xiao jia Luo

    Citation: Journal of Medical Case Reports 2019 13:106

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  5. Content type: Case report

    Hurler–Scheie syndrome is an intermediate form of mucopolysaccharidosis type I which is a rare lysosomal storage disorder caused by the deficiency or complete absence of enzyme alpha-L-iduronidase activity. We...

    Authors: Hamid Assadeck, Moussa Toudou Daouda, Harouna Bako and Fatimata Hassane Djibo

    Citation: Journal of Medical Case Reports 2019 13:102

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  6. Content type: Case report

    Osteochondritis dissecans of the knee is a prevalent pathology in young, active people that is brought about by either traumatic, developmental, or iatrogenic etiologies.

    Authors: Mikel Sánchez, Diego Delgado, Ane Garate, Pello Sánchez, Sabino Padilla and Juan Azofra

    Citation: Journal of Medical Case Reports 2019 13:105

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  7. Content type: Case report

    There are reports of the familial occurrence of Kawasaki disease but only a few reports described Kawasaki disease in siblings. However, the familial cases were not simultaneous. In these patients the idea of ...

    Authors: M. C. Maggio, R. Cimaz, A. Alaimo, C. Comparato, D. Di Lisi and G. Corsello

    Citation: Journal of Medical Case Reports 2019 13:104

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  8. Content type: Case report

    Hypophosphatasia is an inherited bone disease characterized by low alkaline phosphatase activity encoded by ALPL. Clinically, hypophosphatasia can be categorized as perinatal, infantile, childhood, and adult form...

    Authors: Kazunori Fukushima, Keiko Kawai-Kowase, Yukio Yonemoto, Makoto Fujiwara, Hiroko Sato, Mahito Sato, Takuo Kubota, Keiichi Ozono and Junich Tamura

    Citation: Journal of Medical Case Reports 2019 13:101

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  9. Content type: Case report

    Greig cephalopolysyndactyly syndrome is a rare multiple congenital anomaly syndrome characterized by the triad of polysyndactyly (preaxial or mixed preaxial and postaxial), macrocephaly, and ocular hypertelori...

    Authors: Martina Siracusano, Assia Riccioni, Antonia Baratta, Maurizia Baldi, Paolo Curatolo and Luigi Mazzone

    Citation: Journal of Medical Case Reports 2019 13:100

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  10. Content type: Case report

    There is no established treatment after failure of proven therapies for patients with metastatic renal cell carcinoma.

    Authors: Masaki Murata, Yohei Ikeda, Go Hasegawa, Yuki Nakagawa and Tsutomu Nishiyama

    Citation: Journal of Medical Case Reports 2019 13:98

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  11. Content type: Case report

    In metastatic renal cell carcinoma, immunotherapy is the only treatment modality associated with a complete and durable response, but severe toxicity limits its usefulness. If toxicity could be eliminated, imm...

    Authors: Apiruk Sangsin, Hideki Murakami, Takaki Shimizu, Satoshi Kato and Hiroyuki Tsuchiya

    Citation: Journal of Medical Case Reports 2019 13:96

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  12. Content type: Case report

    Adefovir dipivoxil is a nucleotide analogue that is approved for treatment of chronic hepatitis B. Adefovir dipivoxil is associated with proximal tubular dysfunction, resulting in Fanconi syndrome, which can c...

    Authors: Tomohisa Kunii, Toshie Iijima, Teruo Jojima, Masanori Shimizu, Masato Kase, Shintaro Sakurai, Takahiko Kogai, Isao Usui and Yoshimasa Aso

    Citation: Journal of Medical Case Reports 2019 13:99

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  13. Content type: Case report

    Papillary thyroid carcinoma is the most common endocrine malignancy. Distant metastasis from differentiated thyroid carcinoma is infrequent and the metastasis rate of papillary thyroid carcinoma is lower than ...

    Authors: Emre Gezer, Alev Selek, İlhan Tarkun, Zeynep Cantürk and Berrin Çetinarslan

    Citation: Journal of Medical Case Reports 2019 13:95

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  14. Content type: Case report

    Pulmonary valve infective endocarditis is a rare diagnosis that is usually associated with immunocompromised states or structurally abnormal hearts. It is unusual for it to occur in structurally normal hearts ...

    Authors: Paul Bamford, Rajeev Soni, Levi Bassin and Anthony Kull

    Citation: Journal of Medical Case Reports 2019 13:97

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  15. Content type: Case report

    Idiopathic intracranial hypertension, also known as pseudotumor cerebri, is a disorder characterized by increased intracranial pressure of unclear pathogenesis in the absence of other structural and obstructiv...

    Authors: Ahmad Samara, Dana Ghazaleh, Brent Berry and Malik Ghannam

    Citation: Journal of Medical Case Reports 2019 13:94

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  16. Content type: Case report

    Chronic abdominal pain is a common clinical problem. However, diagnosing chronic abdominal pain often requires detailed diagnostic evaluations in addition to sufficient history taking and physical examination,...

    Authors: Tsunetaka Kijima, Ryoji Hyakudomi, Tatsuya Hashimoto, Akari Kusaka, Toshihiko Nakatani and Yutaka Ishibashi

    Citation: Journal of Medical Case Reports 2019 13:93

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  17. Content type: Case report

    Cysticercosis is a zoonotic disease. It is caused by the larval form of the pork tapeworm Taenia solium. This disease is a public health problem in a country like India, but its incidence is underestimated. With ...

    Authors: Tummidi Santosh, Nagiredla Puneeta, Manoj Kumar Patro and Pravin Gaikwad

    Citation: Journal of Medical Case Reports 2019 13:92

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  18. Content type: Case report

    Angiolymphoid hyperplasia with eosinophilia is a rare nodular skin tumor characterized by eosinophilic invasion and vascular proliferation. Previous reports suggested that irritation and inflammation are the c...

    Authors: Naohiro Oka, Shunji Nishimura, Hiroki Tanaka, Kazuhiko Hashimoto, Ryosuke Kakinoki and Masao Akagi

    Citation: Journal of Medical Case Reports 2019 13:87

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  19. Content type: Case report

    Immune checkpoint inhibitors are a promising class of anticancer drugs. The clinical benefits afforded by immune checkpoint inhibitors can be accompanied by immune-related adverse events that affect multiple o...

    Authors: Nobumasa Ohara, Michi Kobayashi, Kazumasa Ohashi, Ryo Ito, Yohei Ikeda, Gen Kawaguchi, Yuichiro Yoneoka, Go Hasegawa and Toshinori Takada

    Citation: Journal of Medical Case Reports 2019 13:88

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  20. Content type: Case report

    Although liver resection is still the best treatment for primary or metastatic hepatic lesions, a conventional surgical approach may be challenging in patients with a history of previous abdominal surgery. We ...

    Authors: Francesco D’Amico, Simone Serafini, Michele Finotti, Marianna Di Bello, Chiara Di Renzo and Umberto Cillo

    Citation: Journal of Medical Case Reports 2019 13:83

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  21. Content type: Case report

    Mixed adenoneuroendocrine carcinomas are highly malignant tumors with both adenocarcinomatous and neuroendocrine components. They can originate in any organ but are more common in the rectum. Due to their rari...

    Authors: S. Semrau, A. Agaimy, M. Pavel, D. Lubgan, D. Schmidt, A. Cavallaro, H. Golcher, R. Grützmann and R. Fietkau

    Citation: Journal of Medical Case Reports 2019 13:82

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  22. Content type: Case report

    Dihydropyrimidine dehydrogenase deficiency secondary to polymorphisms in the DPYD gene can lead to significant toxicity associated with the administration of fluoropyrimidine chemotherapy.

    Authors: Deborah Mukherji, Sarah Abdel Massih, Arafat Tfayli, Mariam Kanso and Walid Faraj

    Citation: Journal of Medical Case Reports 2019 13:76

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  23. Content type: Case report

    Vascular closure devices have been widely used to achieve rapid hemostasis after percutaneous catheterization procedures via the common femoral artery. The EXOSEAL vascular closure device is a device that can ...

    Authors: Ryota Urata, Tetsuya Nomura, Yusuke Hori, Kenichi Yoshioka, Hiroshi Kubota, Daisuke Miyawaki, Takeshi Sugimoto, Masakazu Kikai, Natsuya Keira and Tetsuya Tatsumi

    Citation: Journal of Medical Case Reports 2019 13:90

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  24. Content type: Case report

    Hypertrophic cardiomyopathy is one of the most common causes of sudden cardiac death in young athletes. Performing, comparing, and monitoring serial electrocardiograms over time can help to detect potential ca...

    Authors: Dan Han, Yan Ji and Hui Tan

    Citation: Journal of Medical Case Reports 2019 13:75

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  25. Content type: Case report

    Segmental arterial mediolysis is a rare nonarteriosclerotic and noninflammatory vascular disease that may cause intraperitoneal bleeding. Scleroderma renal crisis is a rare complication of systemic sclerosis, ...

    Authors: Shohei Kaneko, Eri Watanabe, Mai Abe, Shinji Watanabe, Hiroki Yabe, Shigehiro Kojima, Kenji Takagi, Keiji Hirai, Yoshiyuki Morishita and Chihiro Terai

    Citation: Journal of Medical Case Reports 2019 13:74

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  26. Content type: Case report

    Langerhans cell histiocytosis previously known as histiocytosis X is a rare disease of children and young adults with a very broad clinical spectrum. In children, its annual incidence is estimated between 0.2–...

    Authors: Salahoudine Idrissa, Hind Cherrabi, Boubacar Efared, Kassim Sidibé, Karima Attaraf, Lamiae Chater and Abderahmane Afifi

    Citation: Journal of Medical Case Reports 2019 13:67

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  27. Content type: Case report

    Malignant peritoneal mesothelioma is a rare aggressive tumor of the peritoneum. We report a rare case of resection of multiple localized malignant peritoneal mesotheliomas.

    Authors: Takashi Miyata, Yuta Fujiwara, Koji Nishijima, Fumio Futagami, Takashi Nakamura and Hiroyuki Takamura

    Citation: Journal of Medical Case Reports 2019 13:66

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  28. Content type: Case report

    Lodgment of a bullet within the orbit is uncommon. The decision to remove these objects poses a challenge to surgeons due to a high risk of complications. Currently, endoscopic transnasal surgery with navigato...

    Authors: Chakapan Promsopa and Usaporn Prapaisit

    Citation: Journal of Medical Case Reports 2019 13:65

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  29. Content type: Case report

    Micronodular thymoma with lymphoid stroma is a rare subtype of thymoma. Here we report a case of micronodular thymoma with lymphoid stroma that was completely resected after incomplete resection 10 years earlier.

    Authors: Yasunori Kaminuma, Masayuki Tanahashi, Haruhiro Yukiue, Eriko Suzuki, Naoko Yoshii, Toshio Fujino, Hiroshi Ogawa and Hiroshi Niwa

    Citation: Journal of Medical Case Reports 2019 13:69

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  30. Content type: Case report

    Secondary aortoenteric fistula is a rare but fatal complication after reconstructive surgery for an aortic aneurysm characterized by abdominal pain, fever, hematochezia, and hematemesis, and the mortality rate...

    Authors: Hiroaki Saito, Yoshitaka Nishikawa, Jun-ichi Akahira, Hajime Yamaoka, Toru Okuzono, Toyoaki Sawano, Masaharu Tsubokura and Kazuhiro Yamaya

    Citation: Journal of Medical Case Reports 2019 13:61

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  31. Content type: Case report

    The coexistence of neuromeningeal cryptococcosis and Kaposi’s sarcoma is not surprising in a patient with human immunodeficiency virus infection and a low CD4 count, although it is rarely described. However, w...

    Authors: Mickael Essouma, Larry N. Tangie, Mazou N. Temgoua, Ulrich Gabin Kenfack, Antonin N. Ndam and Celestin Danwang

    Citation: Journal of Medical Case Reports 2019 13:86

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  32. Content type: Case report

    The trigeminal autonomic cephalalgias are a group of primary headache syndromes marked by severe head pain and associated cranial autonomic symptoms which can include a full or partial Horner’s syndrome. Rarel...

    Authors: Todd D. Rozen and Matthew T. Kline

    Citation: Journal of Medical Case Reports 2019 13:60

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  33. Content type: Case report

    Clinically silent somatotroph adenoma is characterized by elevated serum growth hormone but without the clinical symptoms of acromegaly, and it is considered rare. The natural history is not well understood, p...

    Authors: Tomohiro Kawaguchi, Yoshikazu Ogawa and Teiji Tominaga

    Citation: Journal of Medical Case Reports 2019 13:85

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  34. Content type: Case report

    Osteosarcomas of the head and neck region are rare entities that comprise < 10% of all osteosarcomas. Multimodality treatment of patients with osteosarcoma is well-established for osteosarcoma in long bones, a...

    Authors: Tadahide Noguchi, Yasushi Sugiura, Naruo Okada, Yoshiyuki Tsuchiya, Jun-ichi Hyasaka, Ken-ichi Sasaguri, Shunji Sarukawa, Akifumi Fujita, Yusuke Amano and Yoshiyuki Mori

    Citation: Journal of Medical Case Reports 2019 13:58

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  35. Content type: Case report

    Insulin autoimmune syndrome is a rare cause of hyperinsulinemic hypoglycemia characterized by autoantibodies to human insulin without previous insulin use. We report a case of a patient with hyperinsulinemic h...

    Authors: Seiji Kobayashi, Houichi Amano, Yoshindo Kawaguchi and Takashi Yokoo

    Citation: Journal of Medical Case Reports 2019 13:79

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  36. Content type: Case report

    Nuclear protein in testis midline carcinoma is a rare, highly metastatic undifferentiated carcinoma that typically arises in midline structures and is characterized by having a fusion involving the nuclear pro...

    Authors: Safwan K. Elkhatib, Beth K. Neilsen, Richard L. Sleightholm, Michael J. Baine and Weining Zhen

    Citation: Journal of Medical Case Reports 2019 13:57

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  37. Content type: Case report

    Desmoplastic small round cell tumor is an extremely rare and aggressive cancer that affects mainly adolescents and young adults. Despite multiple therapeutic strategies, most patients have resistant disease wi...

    Authors: Natalia Brenneken Duarte Ambar, Maria Teresa de Seixas Alves, Henrique Manoel Lederman, Simone Abib, Alexandre Alberto Barros Duarte and Eliana Monteiro Caran

    Citation: Journal of Medical Case Reports 2019 13:77

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  38. Content type: Case report

    A giant congenital cervical teratoma is often highly vascularized; thus, in addition to a life-threatening airway occlusion at birth it comprises a high risk for significant and lethal blood loss during resect...

    Authors: Ori Hochwald, Ziv Gil, Arie Gordin, Zeev Winer, Ron Avrahami, Eitan Abargel, Asaad Khoury, Amit Lehavi, Philippe Abecassis, Liron Eldor, Ofer Ben-Izhak, Liron Borenstein-Levin, Ran Stienberg and Amir Kugelman

    Citation: Journal of Medical Case Reports 2019 13:73

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  39. Content type: Case report

    Gastric adenocarcinoma is a known complication of partial gastrectomy. Jaundice from gastric adenocarcinoma usually occurs in the setting of hepatic nodal or parenchymal metastasis. This case demonstrates an u...

    Authors: Karl Vaz, Raphael P. Luber, Catriona McLean, Jan Frank Gerstenmaier and Stuart K. Roberts

    Citation: Journal of Medical Case Reports 2019 13:72

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  40. Content type: Case report

    Polyarteritis nodosa is a disease that presents with necrotizing vasculitis in small and medium-sized arteries. It may occur in various organs, but approximately half of cases have gastrointestinal involvement...

    Authors: Saori Yajima, Hiroshi Asano, Hiroyuki Fukano, Yasuhiro Ohara, Nozomi Shinozuka, Chih-Ping Li and Taketo Yamada

    Citation: Journal of Medical Case Reports 2019 13:55

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  41. Content type: Case report

    Periprosthetic joint infections are a major challenge for treating physicians. Musculoskeletal infections with Mycobacterium bovis are extremely rare, with an assumed incidence of 0.08–0.1%. Consequently, peripro...

    Authors: Emanuel Kuner, Jens Arne Jöckel, Rene Orler and Reto Nüesch

    Citation: Journal of Medical Case Reports 2019 13:54

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