Articles

Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report

Progressive supranuclear palsy is a neurodegenerative condition that worsens over time. Given the lack of targeted treatments, patients with severe progressive supranuclear palsy have very low life expectancy.

Authors: Huiping Li, Fang Yuan, Yaming Du, Tao Pan, Wanxin Wen, Shaoxue Li, Lixin Wang and Aili Lu

Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report

Uterine sarcoma accounts for 3–7% of uterine malignant neoplasms. It is more aggressive than epithelial neoplasms, and patients have a poor prognosis. Rhabdomyosarcoma is classified as a heterologous uterine s...

Authors: Soheila Aminimoghaddam, Ali Rahbari and Roghayeh Pourali

Interferon-induced sarcoidosis with uveitis as the initial symptom: a case report and review of the literature

In recent years, numerous studies have reported the development or exacerbation of sarcoidosis due to interferon therapy. However, ocular lesions rarely present as initial symptoms. Herein, we describe a rare ...

Authors: Ai Kato, Mami Ishihara and Nobuhisa Mizuki

Transient congenital hyperinsulinism and hemolytic disease of a newborn despite rhesus D prophylaxis: a case report

In neonates, rhesus D alloimmunization despite anti-D immunoglobulin prophylaxis is rare and often unexplained. Rhesus D alloimmunization can lead to hemolytic disease of the newborn with anemia and unconjugat...

Authors: Sandra Simony Tornoe Riis, Marianne Hoerby Joergensen, Kristina Fruerlund Rasmussen, Steffen Husby, Jane Preuss Hasselby, Lise Borgwardt, Klaus Brusgaard, Christina Ringmann Fagerberg and Henrik Thybo Christesen

Symptomatic severe acute respiratory syndrome coronavirus 2 reinfection in a lupus patient treated with hydroxychloroquine: a case report

Hydroxychloroquine and chloroquine have been used for hospitalized coronavirus disease 2019 patients because of their antiviral and anti-inflammatory function. However, little research has been published on th...

Authors: Astrid Muyldermans, Piet Maes, Tony Wawina-Bokalanga, Tine Anthierens, Olivier Goldberg, Magali Bartiaux, Oriane Soetens, Ingrid Wybo, Sigi Van den Wijngaert and Denis Piérard

Correction to: May–Thurner syndrome, a diagnosis to consider in young males with no risk factors: a case report and review of the literature

Authors: Joel Hng, Shu Su and Noel Atkinson

Inferior vena cava thrombosis as a possible cause of nephrotic-range proteinuria: two case reports

Nephrotic-range proteinuria is a common reason for nephrological consultation in clinical practice. The differential diagnosis is wide, and generally focuses on different forms of glomerulonephritis, but other...

Authors: Yana Apostolova, Patricia Mehier, Salah D. Qanadli and Menno Pruijm

New Delhi metallo-β-lactamase-1 among Escherichia coli strains isolated from leukemia patients in Iran: two case reports

Escherichia coli has appeared as an important opportunistic pathogen responsible for nosocomial infections in patients with immunodeficiency, particularly in leukemia patients. New Delhi metallo-beta-lactamase is...

Authors: Mahdane Roshani, Alireza Goodarzi, Sanaz Dehbashi, Farhad Afrasiabi, Hossein Goudarzi, Ali Hashemi and Mohammad Reza Arabestani

Irreversible electroporation for pancreatic cancer using intraprocedural cone-beam computed tomography fusion navigation: a case report

Patients diagnosed with locally advanced pancreatic cancer are usually not eligible for surgical resection because of significant vascular involvement. Stereotactic body radiation therapy and chemotherapy are ...

Authors: Sriram Rao, Thanh-Lan Bui, Ali Sasani, Ben Sadeghi, Anvesh Macherla, Roozbeh Houshyar and Nadine Abi-Jaoudeh

Carboxymethylcellulose excipient allergy: a case report

Excipients are widely used in pharmaceuticals, detergents, food, and drink because of their properties of low toxicity and hypoallergenicity. The excipient carboxymethylcellulose is used extensively as a thick...

Authors: Katherine Townsend, James Laffan and Grant Hayman

Effectiveness of convalescent plasma therapy in eight non-intubated coronavirus disease 2019 patients in Indonesia: a case series

Severe acute respiratory syndrome coronavirus 2, the cause of coronavirus disease 2019, has become a global pandemic. Currently, there is no definitive treatment for coronavirus disease 2019. Convalescent plas...

Authors: Theresia Monica Rahardjo, Elizabeth Yogipranata, Ardian Hediyanto Naswan, Fitri Rahayu Sari, Fajar Budiono, Hernawati Permatasari and C. H. R. Driantik Chuntari

Bilateral basal ganglia ischemia associated with COVID-19: a case report and review of the literature

Coronavirus disease 2019, caused by the severe acute respiratory syndrome coronavirus 2, has a broad clinical spectrum, from asymptomatic to multi-organ dysfunction. Acute cerebrovascular events associated wit...

Authors: Khurram Khaliq Bhinder, Ahsun Rizwan Siddiqi, Muhammad Junaid Tahir, Hamza Maqsood, Irfan Ullah and Zohaib Yousaf

Afatinib for the treatment of advanced non-small-cell lung cancer harboring an epidermal growth factor receptor exon 18 E709_T710delinsD mutation: a case report

The discovery of epidermal growth factor receptor oncogenic driver mutations has changed the therapeutic landscape of advanced non-small cell lung cancer in the past decade. Since the introduction of next-gene...

Authors: Lander Van Acker, Dieter Stevens, Karim Vermaelen and Veerle Surmont

Augmentation mammaplasty by superolateral thoracic flap: a case report

The lateral chest wall is intimately associated with the esthetics of the breast. Patients with massive weight loss often have excess skin and fat in the lateral thoracic region causing functional, esthetic, a...

Authors: Elise Lupon, Benoit Chaput and Thomas Meresse

Uncertainty of leukoencephalopathies: a case report

Adult-onset leukoencephalopathies are a group of heterogeneous disorders characterized by white matter abnormalities. Leukoencephalopathy is usually encountered in children, but here we report a case with adul...

Authors: Mohamed A. Taha and T. Scott Diesing

Carney’s triad in an adult male from a tertiary care center in India: a case report

Carney’s triad is a rare syndrome comprising gastrointestinal stromal tumor, extra-adrenal paraganglioma, and pulmonary chondroma along with newer additions of adrenal adenoma and esophageal leiomyoma. The tri...

Authors: Ghazal Tansir, Nihar Ranjan Dash, Saurabh Galodha, Prasenjit Das, Shamim Ahmed Shamim and Sameer Rastogi

Guillain–Barré syndrome with bilateral facial diplegia secondary to severe acute respiratory syndrome coronavirus-2 infection: a case report

The new coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) owing to its similarity to the previous severe acute respiratory syndrome (SARS), is characterized by causing, in most...

Authors: Natalia Ramirez, David Ujueta, Luis Felipe Diaz, Lucila Emilse Folleco, Andrea Rodríguez, Ivan Gaona and Mauricio O. Nava-Mesa

Pneumatosis intestinalis associated with lenvatinib during thyroid cancer treatment: a case report

Pneumatosis intestinalis is a rare disease characterized by gas-filled cysts within the submucosa or serosa of the intestinal tract. In recent years, pneumatosis intestinalis was reported in patients undergoin...

Authors: Soji Toda, Hiroyuki Iwasaki, Daisuke Murayama, Maya Isoda, Hirotaka Nakayama, Nobuyasu Suganuma and Katsuhiko Masudo

“I took it off most of the time 'cause I felt comfortable”: unmasking, trusted others, and lessons learned from a coronavirus disease 2019 reinfection: a case report

Severe acute respiratory syndrome coronavirus 2 reinfection prevalence is unknown. It is essential to understand reinfection symptoms and, importantly, the lived experience.

Authors: Jacinda K. Dariotis, Stephanie M. Sloane and Rebecca Lee Smith

Shrinkage of a pituitary metastasis of melanoma induced by pembrolizumab: a case report

Pituitary metastases are rare, often deriving from lung or breast cancer owing to the upper vena cava proximity. Pituitary metastases can manifest with signs and symptoms of pituitary tumors, consequent to mas...

Authors: Giuseppe Giuffrida, Francesco Ferraù, Ylenia Alessi and Salvatore Cannavò

Sigmoid volvulus in pregnancy: a case report

Sigmoid volvulus in pregnancy is a rare cause of intestinal obstruction with high maternal and fetal morbidity and mortality if not diagnosed and managed early.

Authors: Jay Lodhia, Joachim Magoma, Joylene Tendai, David Msuya, Jamil Suleiman and Kondo Chilonga

Gummatous neurosyphilis in an elderly patient in the Australian outback: a case report

Neurosyphilis is an infection caused by the spirochete Treponema pallidum, which causes infiltration and thickening of brain meninges. Despite being an Old World disease, the rates of infection continue to rise. ...

Authors: Nilesh Anand Devanand and Krishnaswamy Sundararajan

Diagnostic challenge and surgical management of Boerhaave’s syndrome: a case series 

Boerhaave’s syndrome is the spontaneous rupture of the esophagus, which requires early diagnosis and treatment. Symptoms may vary, and diagnosis can be challenging.

Authors: Jiayue Wang, Degang Wang and Jianjiao Chen

Progressive pseudorheumatoid dysplasia misdiagnosed as juvenile idiopathic arthritis: a case report

Progressive pseudorheumatoid dysplasia is a rare, autosomal recessively inherited, noninflammatory musculoskeletal disorder caused by mutations occurring in the WNT1-inducible signaling pathway protein 3 gene....

Authors: Anjumanara Anver Omar, Salman Ahmed, John Chris Rodrigues, Allan Kayiza and Lawrence Owino

Disseminated tuberculosis with myelofibrosis presentation: a case report

Primary myelofibrosis is a rare myeloproliferative disorder in middle-aged and old adults and should be distinguished from secondary and reactive causes of bone marrow fibrosis because, in reactive fibrosis, t...

Authors: Mahdi Khatuni, Marziyeh Ghalamkari, Fereshteh Ameli and Habibeh Yekehtaz

Recommendations on service delivery to help reduce suffering and anxiety in patients and caregivers post-hematopoietic cell transplantation: a case report

The aim of this study is to highlight the importance of having a central case managing team and to make some strong recommendations that can have a positive impact on the lives of hematopoietic stem cell trans...

Authors: Jaleel Mohammed, Hadeel R. Bakhsh, Cliodhna Craig and Shahrukh K. Hashmi

Acute psychosis and serotonin syndrome in the setting of “Triple-C” overdose: a case report

Over-the-counter medication overdose is a difficult diagnostic challenge for many physicians as common drug screening assays cannot detect these substances. We present a case of acute psychosis, serotonin synd...

Authors: Roudi Bachar, John Robert Majewski, Christopher Shrack and Anthony El-Khoury

Primary diffuse large B-cell lymphoma of the prostate: a case report and review of the literature

Primary lymphoma of the prostate is an exceedingly rare disease, with diffuse large B-cell lymphoma being the most common known subtype in a small number of reported cases. Due to its low prevalence, there has...

Authors: Mengwei Ren and Yanli Liu

Post-coronavirus disease 2019 polyneuropathy with significant response to immunoglobulin therapy: a case report

The symptoms of coronavirus disease 2019, caused by the novel severe acute respiratory syndrome coronavirus 2, were originally assumed to be mainly respiratory. With increasing knowledge, however, it turned ou...

Authors: A. Saleh, R. Jung, S. Tonner, F. Hornof and M. Strittmatter

Chronic gastrointestinal bleeding caused by a Dieulafoy’s lesion in the small intestine: a case report

Dieulafoy’s lesion, first found by Paul Georges Dieulafoy, is an infrequent but important cause of recurrent upper gastrointestinal bleeding. The bleeding is usually severe, but patients rarely present with ch...

Authors: Javad Salimi, Mohamad Behzadi, Alireza Ramandi, Mehdi Jafarinia, Hamid Zand and Mohammad Pirouzian

Resolution of pituitary microadenoma after coronavirus disease 2019: a case report

This report describes the case of a patient whose pituitary microadenoma resolved after he contracted coronavirus disease 2019. To our knowledge, this is one of the first reported cases of pituitary tumor reso...

Authors: Salah Raishan, Mohammed Alsabri, Ann Mary Hanna and Matthew Brett

Atypical involvement of central nervous system in classic Hodgkin lymphoma: a case report

Hodgkin lymphoma is a systemic disease that commonly involves the cervical, supraclavicular, and mediastinal lymph nodes. The involvement of central nervous system in Hodgkin lymphoma is extremely rare, and di...

Authors: Shanila Ahmed, Babar Irfan, Muhammad Raza and Ghulam Haider

Malignant pericardial effusion as a primary manifestation of metastatic colon cancer: a case report

Pericardial neoplastic involvement is rarely related to primary tumors of the pericardium and is most often caused by spread from other primary sites, such as lung and breast carcinomas, hematological malignan...

Authors: Milena Brachmans Mascarenhas Neves, Mirella Velasco Stival, Yuri Costa Sarno Neves, Jordânia Gonçalves Pereira da Silva, Daniela Borges da Rocha Macedo, Bianca Mendes Carnevalli, Alana Moura Fé e Silva, Claudia Vaz de Melo Sette, Stephane Tomaz da Luz and Daniel de Iracema Gomes Cubero

Immunophenotypic challenges in diagnosis of CD79a negativity in a patient with B acute lymphoblastic leukemia harboring intrachromosomal amplification of chromosome 21: a case report

Being expressed in all stages of B-cell development and having a significant value on the European Group for the Immunological Characterization of Acute Leukemias scoring system, CD79a is considered as an exce...

Authors: A. Berhili, M. Bensalah, J. ElMalki, A. Elyagoubi and R. Seddik

Life-threatening diarrhea in neuroendocrine tumors: two case reports

Neuroendocrine tumors are rare, heterogeneous neoplasms that produce a wide variety of clinical symptoms. Diarrhea in neuroendocrine tumors is incredibly common and is usually benign in nature. We report two e...

Authors: Emma Gordon, David L. Chan, Jennifer Arena, Elizabeth Bernard, Emily Carr-Boyd, Stephen J. Clarke, Malinda Itchins, Diana Learoyd, Neomal Sandanayake and Nick Pavlakis

Successful treatment with radiation therapy for desmoid-type fibromatosis with unilateral hydronephrosis: a case report

Desmoid-type fibromatosis is a rare disease that can result in hydronephrosis. Hydronephrosis associated with desmoid-type fibromatosis often requires surgery or ureteral stent insertion. Although radiation th...

Authors: Yojiro Ishikawa, Rei Umezawa, Takaya Yamamoto, Noriyoshi Takahashi, Kazuya Takeda, Yu Suzuki and Keiichi Jingu

Streptococcus gallolyticus endocarditis on a prosthetic tricuspid valve: a case report and review of the literature

Streptococcus gallolyticus subspecies gallolyticus is a known pathogen that causes infective endocarditis, and most cases involve the left heart valves. We present the first reported case of prosthetic tricuspid ...

Authors: Raz Shapira, Tamir Weiss, Elad Goldberg, Eytan Cohen, Ilan Krause, Ram Sharony and Idan Goldberg

Acute pancreatitis in a COVID-19 patient in Brazil: a case report

The consequences of the coronavirus disease 2019 pandemic have already exceeded 10 million infected and more than 560,000 deaths worldwide since its inception. Currently, it is known that the disease affects m...

Authors: Caroline Petersen da Costa Ferreira, Kalynne Rodrigues Marques, Gustavo Henrique Ferreira de Mattos and Tércio de Campos

Chemorefractory extranodal nasal-type natural-killer/T-cell lymphoma with great response to pembrolizumab in a young patient: a case report

Extranodal, natural-killer/T-cell lymphoma of nasal type is a rare but aggressive disease usually presenting as progressive necrotic lesions in the nasal cavity that responds poorly to chemotherapy. In this pa...

Authors: Fatemeh Adabifirouzjaei, Bharam Khazai, Ghazaleh Azami and Ghazaleh Shoja-e-Razavi

Fatal large-vessel cerebrovascular infarct presenting with severe coronavirus disease 2019 in a 39-year-old patient: a case report

Emerging reports are describing stroke in young, otherwise healthy patients with coronavirus disease 2019, consistent with the theory that some of the most serious complications of coronavirus disease 2019 are...

Authors: Nicolas Koslover, Marc Hardwick, Alexander Grundmann and Tamara Levene

Gastric perforation leading to the diagnosis of classic Ehlers–Danlos syndrome: a case report

Ehlers–Danlos syndrome is a clinically and genetically heterogeneous group of heritable connective tissue disorders caused by a defect in collagen synthesis and structure. The vascular subtype (Ehlers–Danlos s...

Authors: Ahad E. Alotaibi, Ohood H. AlAamer, Mohammed A. Bawazeer and Ali A. Alzahrani

Fragmentation of microspheres after bronchial artery injection: a case report and review of the literature

Massive hemoptysis due to aspergilloma is a rare but life-threatening complication. Bronchial artery embolization is recommended as a definitive treatment for massive hemoptysis. Polyvinyl alcohol is widely us...

Authors: Wei Luo, Tongchen Hu, Yu Mao and Qi Yu

A neonate with spontaneous arterial limb ischemia and an aneurysm of the oval foramen: a case report

In this case report, we describe a very rare case of severe limb ischemia due to an arterial embolus caused by an aneurysm of the oval foramen in a term-born infant that occurred in the first few hours after b...

Authors: J. J. van Vonderen, J. M. H. Keus, J. van Schaik, F. J. Smiers, D. J. ten Harkel and E. Lopriore

Meglitinide (repaglinide) therapy in permanent neonatal diabetes mellitus: two case reports

Permanent neonatal diabetes mellitus (PNDM) presents with dehydration and hyperglycemia, which usually occurs during the first 12 months of life. Activating mutations of beta-cell adenosine triphosphate-sensit...

Authors: Maryam Razzaghy-Azar, Mitra Nourbakhsh, Ali Talea, Mahsa Mohammad Amoli, Mona Nourbakhsh and Bagher Larijani

Postpartum ovarian vein thrombosis manifesting as acute appendicitis: a case report

Postpartum ovarian thrombosis is an uncommon condition. It appears with the nonspecific, predominantly right-sided abdominal symptoms and must be differentiated from other acute visceral conditions. If left un...

Authors: Christos Tsitlakidis, Khalil Ibrahim Salim Al Ajmi, Alya Yousuf Al Madhani and Adel Hassan Ahmidat

Metoclopramide-induced acute dystonic reactions: a case report

Acute dystonic reactions caused by drugs are uncommon in daily practice, whether in outpatient or in emergency settings. Such types of unfavorable reaction may cause the treating physician’s working diagnosis ...

Authors: Ritesh Chaudhary, Gyanendra Malla and Monika Kadayat

Metastatic choriocarcinoma in a young woman presenting as thyroid storm: a case report

Thyroid storm is an endocrine emergency and life-threatening condition discovered in 1926. There is no specific laboratory parameter that can differentiate or distinguish between thyroid storm and primary hype...

Authors: Muhammad Saleem, Sher M. Sethi, Abrar Ali and Zareen Kiran

Implantation of an attachment tube preserves knee extension after nonunion of Felix IV fracture: a case report

While commonly utilized to fix tissue and muscles to megaprostheses to restore function and stability after tumor surgery, an attachment tube was used as a synthetic reconstruction of the knee joint’s extensio...

Authors: Alena Richter, Henning Windhagen and Max Ettinger

Combined therapy with intravitreal aflibercept and subtenon corticosteroids in eyes with severe diabetic papillopathy: two case reports

Diabetic papillopathy is a rare diagnosis of exclusion characterized by unilateral or bilateral optic disc edema with variable degrees of visual loss. Although the visual prognosis has been generally reported ...

Authors: Ilir Arapi, Piergiorgio Neri, Alfonso Giovannini and Arjeta Grezda

When obstetrics–gynecology specialists need to call an ophthalmologist urgently: a case report

We report here a case of a healthy 23-year-old female patient who was assessed at the gynecology emergency department for genital ulcers, fever, and blurred vision. After suspicion of herpes simplex virus-2 le...

Authors: S. Masmejan, Y. Guex-Crosier, C. Diserens, M. Vouga, A. S. Clottu, C. Ribi, P. Mathevet and M. Jacot-Guillarmod