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  1. Sheehan's syndrome is hypopituitarism due to pituitary gland necrosis resulting from hemorrhagic shock during pregnancy. It is a rare complication with varied manifestations and a considerable delay in diagnosis.

    Authors: Abere Genetu, Yibeltal Anemen, Sinshaw Abay, Simachew Anemen Bante and Kebadnew Mulatu Mihrete

    Citation: Journal of Medical Case Reports 2021 15:229

    Content type: Case report

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  2. Hypotony maculopathy has been classically reported as a complication of glaucoma surgery or ocular trauma. There have been only a few reports of hypotony maculopathy following pars plana vitrectomy (PPV). Here...

    Authors: Yun Jeong Lee and Se Joon Woo

    Citation: Journal of Medical Case Reports 2021 15:255

    Content type: Case report

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  3. Primitive neuroendocrine prostate neoplasms are rarely reported. This entity comprises carcinoïd tumors and poorly differentiated neuroendocrine tumors, mainly those of the small-cell type. Large-cell-type pri...

    Authors: Walid Sleiman, Omar Karray, Mikael Abi Abdallah, Sarah Bleichner-Perez, Jihen Kourda, Mihaela Cosma-Opris, Sabine Assouad, Jean-Charles Riffaud, Stéphane Bart and Patrick Coloby

    Citation: Journal of Medical Case Reports 2021 15:254

    Content type: Case report

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  4. The plasma serine protease inhibitor alpha 2-antiplasmin (α2-AP, otherwise known as α2-plasmin inhibitor) is a rapid-acting plasmin inhibitor recently found in human plasma, which seems to have a significant role...

    Authors: Bashir Abdrhman Bashir Mohammed

    Citation: Journal of Medical Case Reports 2021 15:238

    Content type: Case report

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  6. Syncopes and transient loss of consciousness affect a large number of patients. Determining the underlying mechanism of a syncope is key to effectively treating and preventing future events. However, given the...

    Authors: Michael Wester, Tanja Bergmann, Martina Müller-Schilling, Lars S. Maier and Samuel T. Sossalla

    Citation: Journal of Medical Case Reports 2021 15:261

    Content type: Case report

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  7. Primary splenic lymphoma represents a rare entity that constitutes less than 1% of non-Hodgkin lymphomas, and less than 2% of all lymphomas. Diffuse large B-cell lymphoma (DLBCL) is the most common histologica...

    Authors: Sawsan Ismail, Filip Ali, Hussein Ajamieh, Samir Kanaan, Rana Issa, Ali Daoud and Zuheir Alshehabi

    Citation: Journal of Medical Case Reports 2021 15:227

    Content type: Case report

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  8. Low-grade endometrial stromal sarcoma is a rare neoplastic growth in the uterine cavity, representing less than 1% of uterine tumors. Such tumors usually affect premenopausal and perimenopausal women, with a m...

    Authors: Omar F. Altal, Ahmed H. Al Sharie, Omar M. Halalsheh, Nour Tashtush, Sarat Shaban, Mahmoud Alfaqih and Abdelwahab Aleshawi

    Citation: Journal of Medical Case Reports 2021 15:262

    Content type: Case report

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  9. Primary malignant melanoma of the esophagus is a rare and aggressive disease that tends to have a poor response to chemotherapies. Previous studies have indicated that currently available treatment for primary...

    Authors: Shingo Ito, Yuji Tachimori, Yuichi Terado, Ryota Sakon, Kazuhiro Narita and Manabu Goto

    Citation: Journal of Medical Case Reports 2021 15:237

    Content type: Case report

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  10. Differentiation syndrome (DS) is a life-threatening complication that may be seen in patients with acute promyelocytic leukaemia undergoing induction therapy with all-trans retinoic acid or arsenic trioxide. I...

    Authors: Sayan Sarkar, Priya Ghosh, Anisha Gehani, Niharendu Ghara and Parthasarathi Bhattacharyya

    Citation: Journal of Medical Case Reports 2021 15:226

    Content type: Case report

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  11. Germline pathogenic variants in the cadherin-1 (CDH1) gene cause a predisposition to hereditary diffuse gastric cancer (HDGC). We report an HDGC case in Vietnam and identify a novel mutation in the CDH1 gene.

    Authors: Dzung Ngoc Thi Dang, Huong Thanh Thi Nguyen, Hoa Dieu Ngo, Bac Manh Tran, Anh Duc Vu, Huy Quang Dang and Van Thanh Ta

    Citation: Journal of Medical Case Reports 2021 15:263

    Content type: Case report

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  12. Although life-threatening hemorrhage is a usual manifestation of acute promyelocytic leukemia (APL), thrombotic events seem to be more common in APL compared to other subtypes of acute leukemia. The treatment ...

    Authors: Shirin Haghighat, Alireza Rezvani and Maral Mokhtari

    Citation: Journal of Medical Case Reports 2021 15:260

    Content type: Case report

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  14. Reduction en mass (REM) is one of the rare complications of inguinal hernia reduction. Although REM can be detected on the basis of specific computed tomography (CT) scan findings, many radiologists are not fa...

    Authors: Khosrow Najjari, Hossein zabihi Mahmoudabadi, Seyed Zeynab Seyedjavadeyn and Reza Hajebi

    Citation: Journal of Medical Case Reports 2021 15:251

    Content type: Case report

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  16. Among cardiac causes for postpartum maternal collapse, severe mitral stenosis is not listed as a potential cause in current literature. We report a rare case of severe mitral stenosis that presented with sever...

    Authors: Abraham Fessehaye, Yared Teshome Tafere and Desalegn Degafu Abate

    Citation: Journal of Medical Case Reports 2021 15:225

    Content type: Case report

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  17. Coronavirus disease 2019 (COVID-19) was first identified in Indonesia in March 2020, and the number of infections has grown exponentially. The situation is at its worst, overwhelming intensive care unit (ICU) ...

    Authors: Hori Hariyanto, Corry Quando Yahya and Ronald Christian Agustinus Aritonang

    Citation: Journal of Medical Case Reports 2021 15:259

    Content type: Case report

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  19. Infectious mononucleosis (IM) and mononucleosis-like illnesses are common viral infectious diseases which are often accompanied by a high fever, pharyngitis and lymphadenopathy in adults, although such infecti...

    Authors: Katsumasa Koyama, Takatoshi Anno, Takashi Urano, Ryo Shigemoto, Shintaro Irie, Fumiko Kawasaki, Miwa Kawanaka, Hirofumi Kawamoto, Hideaki Kaneto and Koichi Tomoda

    Citation: Journal of Medical Case Reports 2021 15:257

    Content type: Case report

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  20. Actinomycosis is a rare inflammatory bacterial disease caused by Actinomyces species which can infrequently affect the large intestine. Disseminated actinomycosis is reported as a rare complication associated wit...

    Authors: Gnanaselvam Pamathy, Umesh Jayarajah, Dayal Sathyajith Gamlaksha, Roshana Constantine and Anura S. K. Banagala

    Citation: Journal of Medical Case Reports 2021 15:224

    Content type: Case report

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  21. Effort rupture of the esophagus or Boerhaave’s syndrome is a rare entity, and prognosis is largely dependent on early diagnosis and treatment. Recurrent effort ruptures are very rare, only reported in a few ca...

    Authors: Adam Zeyara, Martin Jeremiasen, Oscar Åkesson, Dan Falkenback, Michael Hermansson and Jan Johansson

    Citation: Journal of Medical Case Reports 2021 15:223

    Content type: Case report

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  23. Prostatic carcinoma is emerging as the most common male malignancy in Nigeria and the second most common male cancer worldwide. Patients often present with locally advances stages, and common sites of metastas...

    Authors: Ifeoluwa S. Olorunsola, Amarachukwu C. Etonyeaku, Blessing O. Lekwa and Olusegun S. Ojo

    Citation: Journal of Medical Case Reports 2021 15:222

    Content type: Case report

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  24. Aggressive squamous cell carcinomas (SCCs) present frequently in the context of chronic skin injury occurring in patients with the congenital blistering disease recessive dystrophic epidermolysis bullosa. Rece...

    Authors: Jena Patel, Nicoline Y. den Breems, Madalina Tuluc, Jennifer Johnson, Joseph M Curry, Andrew P. South and Raymond J. Cho

    Citation: Journal of Medical Case Reports 2021 15:252

    Content type: Case report

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  25. Pembrolizumab and other immune checkpoint inhibitors are the emerging treatment for selected, high-grade malignancies. However, a small number of patients are unable to tolerate its adverse effects, leading to...

    Authors: Chia-Yi Tian, Yang-Hao Ou, Shih-Liang Chang and Chih-Ming Lin

    Citation: Journal of Medical Case Reports 2021 15:244

    Content type: Case report

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  26. Immunoglobulin G4 (IgG4)-related disease is a chronic inflammatory disease that was recognized in 2011. Pleuritis associated with IgG4-related disease is rare and can be difficult to diagnose. Although there h...

    Authors: Hiroki Shimada, Yuto Kato, Miyuki Okuda, Koji Fukuda, Nobuya Tanaka, Yutaro Okuda and Akihiko Yoshizawa

    Citation: Journal of Medical Case Reports 2021 15:241

    Content type: Case report

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  27. Extranodal natural killer/T-cell lymphoma is a rare, aggressive non-Hodgkin lymphoma that is treated upfront mostly with L-asparaginase containing regimens. Relapsed extranodal natural killer/T-cell lymphoma is a...

    Authors: Elizabeth McGehee, Hetalkumari Patel, Caroline Pearson, Keri Clements, Jesse Manuel Jaso, Weina Chen, Alexandra Callan, Neil Desai and Praveen Ramakrishnan Geethakumari

    Citation: Journal of Medical Case Reports 2021 15:221

    Content type: Case report

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  28. Dermatochalasis of the upper eyelids (blepharochalasis) is a typical age-related change in the upper third of the face and a major concern for facial aesthetics. Nowadays both surgical and nonsurgical interven...

    Authors: Luca Maione, Valeriano Vinci, Domenico Costanzo, Andrea Battistini, Andrea Lisa and Alessandra Di Maria

    Citation: Journal of Medical Case Reports 2021 15:248

    Content type: Case report

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  29. Mortality after elective pancreatic surgery in modern high-volume centers is very low. Morbidity remains high, affecting 20–40% of patients. Late postpancreatectomy hemorrhage is a rare but potentially lethal ...

    Authors: Adam Zeyara, Bobby Tingstedt and Bodil Andersson

    Citation: Journal of Medical Case Reports 2021 15:245

    Content type: Case report

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  30. Adjuvant endocrine therapy is recommended for the treatment of hormone-receptor-positive breast cancer. Aromatase inhibitors are associated with significant musculoskeletal adverse effects, likely through grow...

    Authors: Sasan Mirfakhraee, Alberto V. Cabo Chan Jr., Niloofar Ganji and Jessica Abramowitz

    Citation: Journal of Medical Case Reports 2021 15:207

    Content type: Case report

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  32. Coronavirus disease 2019 (COVID-19) is a global pandemic. The disease, typically characterized by bilateral pulmonary infiltrates and profound elevation of inflammatory markers, can range in severity from mild...

    Authors: Dmitriy A. Gagarkin, Keith E. Dombrowski, Keyur B. Thakar and John C. DePetrillo

    Citation: Journal of Medical Case Reports 2021 15:219

    Content type: Case report

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  33. The outbreak of coronavirus disease 2019 (COVID-19) started in December 2020, and is a global problem now. There are several sets of established data regarding computed tomography (CT) findings in COVID-19 pne...

    Authors: Afshin Rakhsha, Zahra Mahboubi-Fooladi and Anya Jafari

    Citation: Journal of Medical Case Reports 2021 15:218

    Content type: Case report

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  34. The median sternotomy approach in sleeve pneumonectomy enables diseased lung ventilation in selected cases, which may reduce the difficulty in achieving anastomosis under intubation of the left main bronchus. ...

    Authors: Hirotoshi Suzuki, Masafumi Noda, Tatsuaki Watanabe, Yasushi Matsuda, Yasushi Hoshikawa and Yoshinori Okada

    Citation: Journal of Medical Case Reports 2021 15:205

    Content type: Case report

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  35. Failed aortofemoral and femoropopliteal bypass grafts in the lower extremity artery usually result in acute limb ischemia. Endovascular treatment and surgical revascularization have been reported for limb salv...

    Authors: Tatsuo Haraki, Taichi Kondo, Izaya Kamei and Takahiro Tanabe

    Citation: Journal of Medical Case Reports 2021 15:204

    Content type: Case report

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  36. Sirenomelia, also called mermaid syndrome, is a rare lethal multi-system congenital deformity with an incidence of one in 60,000–70,000 pregnancies. Sirenomelia is mainly characterized by the fusion of lower l...

    Authors: Asiyeh Shojaee, Firooze Ronnasian, Mahdiyeh Behnam and Mansoor Salehi

    Citation: Journal of Medical Case Reports 2021 15:217

    Content type: Case report

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  37. Because of the rarity of primary hepatic lymphomas, diagnosis of this disease entity may often be difficult, and performing a liver biopsy is the only way to establish a definitive diagnosis. Recently, endosco...

    Authors: Kenichiro Nishikawa, Koji Katsuta, Syota Tanaka, Kodai Fujibe, Aiji Hattori, Yasunori Shiono, Michiaki Oiwa and Shimpei Matsusaki

    Citation: Journal of Medical Case Reports 2021 15:199

    Content type: Case report

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  38. Thoracoscopic segmentectomy of the lateral and posterior basal segments is extremely technically challenging. Appropriate segmentectomy requires exposure and recognition of the branches of the bronchi and pulm...

    Authors: Shota Mitsuboshi, Hiroaki Shidei, Akihiro Koen, Hideyuki Maeda, Hiroe Aoshima, Tamami Isaka and Masato Kanzaki

    Citation: Journal of Medical Case Reports 2021 15:196

    Content type: Case report

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  40. Routine myomectomy at the time of cesarean section has been condemned in the past due to fear of uncontrolled hemorrhage and peripartum hysterectomy. It is still a topic of debate worldwide. However, in recent...

    Authors: Priyanka Garg and Romi Bansal

    Citation: Journal of Medical Case Reports 2021 15:193

    Content type: Case report

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  41. Thromboangiitis obliterans or Buerger’s disease is a form of peripheral vascular disease in young male smokers. The involvement of the intestine occurs in only about 2% of the cases, when they may present as a...

    Authors: Swastik Sourav Mishra, Tushar Subhadarshan Mishra, Suvradeep Mitra and Pankaj Kumar

    Citation: Journal of Medical Case Reports 2021 15:215

    Content type: Case report

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  42. Immune checkpoint inhibitors have recently become widely used for the management of advanced cancer patients. During the development of immune checkpoint inhibitors (ICPIs), it was quickly recognized that they...

    Authors: Fumi Kikuchi, Takanobu Saheki, Hitomi Imachi, Toshihiro Kobayashi, Kensaku Fukunaga, Tomohiro Ibata, Seisuke Sato, Natsuki Ban, Jingya Lyu, Salimah Japar and Koji Murao

    Citation: Journal of Medical Case Reports 2021 15:214

    Content type: Case report

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  43. Vertical transmission of coronavirus disease 2019 (COVID-19) from mother to newborn infant is doubtful, and very little is known about disease severity and neonatal outcome.

    Authors: Roya Farhadi, Shahrokh Mehrpisheh, Vajiheh Ghaffari, Mohammadreza Haghshenas and Aghdas Ebadi

    Citation: Journal of Medical Case Reports 2021 15:213

    Content type: Case report

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  44. Dermatologic toxicity is a very common immune-related adverse event (irAE) for patients with melanoma who are receiving immune checkpoint inhibitor therapy (ICI). Concurrent skin infection, such as in the case...

    Authors: Mingjia Li, Natalie Spaccarelli, Kari Kendra, Richard C. Wu and Claire Verschraegen

    Citation: Journal of Medical Case Reports 2021 15:212

    Content type: Case report

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  45. Homologous recombination deficiency is a marker of response to poly(ADP-ribose) polymerase inhibitors in different cancer types including ovary, prostate, and pancreatic cancer. To date, no report about poly(A...

    Authors: Rosa Montero-Macias, Meriem Koual, Céline Crespel, Marie Aude Le Frére-Belda, Hélène Blons Hélène, Huyen-Thu Nguyen-Xuan, Simon Garinet, Géraldine Perkins, Vincent Balay, Catherine Durdux, Marie Florin, Hélène Péré and Anne-Sophie Bats

    Citation: Journal of Medical Case Reports 2021 15:210

    Content type: Case report

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  46. Methimazole (MMI) is the treatment of choice for patients with Graves’ disease. The major drawback of this treatment is the relapse of hyperthyroidism in half of the patients after discontinuation of the recom...

    Authors: Fereidoun Azizi, Atieh Amouzegar and Hengameh Abdi

    Citation: Journal of Medical Case Reports 2021 15:189

    Content type: Case report

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  47. Coronavirus disease 2019 has become a health problem spreading worldwide with pandemic characteristics since March 2020. Post coronavirus disease 2019 symptoms are more frequent than initially expected, with f...

    Authors: Andreas Rembert Koczulla, Antje Stegemann, Rainer Gloeckl, Sandra Winterkamp, Bernd Sczepanski, Tobias Boeselt, Jan Storre and Michael Dreher

    Citation: Journal of Medical Case Reports 2021 15:211

    Content type: Case report

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  48. Dementia is among the most common chronic noncommunicable neurodegenerative diseases. In the long term, it causes disability and loss of autonomy and independence. It is estimated that there are 35.6 million p...

    Authors: Letícia Zanetti Marchi, Rayssa Gabriela Dantas Ferreira, Gabriella Nayara Siqueira de Lima, Jessyca Alves Silvestre da Silva, Daniel Marinho Cezar da Cruz, Bernardino Fernandez-Calvo and Suellen Mary Marinho dos Santos Andrade

    Citation: Journal of Medical Case Reports 2021 15:185

    Content type: Case report

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  49. Aripiprazole is a third-generation atypical antipsychotic drug that acts as a stabilizer of the dopaminergic and serotonergic system. As partial agonist of the dopamine (D2) and serotonin (5-HT1A) receptors, ...

    Authors: Rosaria Nardello, Fulvio Guccione, Claudia Gliubizzi, Antonio Marino, Mariarita Capizzi and Salvatore Mangano

    Citation: Journal of Medical Case Reports 2021 15:209

    Content type: Case report

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  50. Although central nervous system tumors are the most common etiology of malignancies in the pediatric age group, choroid plexus carcinomas are rare, with an annual incidence rate of 0.10 per 100,000 children.

    Authors: Patel Zeeshan Jameel, Ashish Varma, Pooja Kumari, Keta Vagha, Jayant Vagha and Sachin Damke

    Citation: Journal of Medical Case Reports 2021 15:184

    Content type: Case report

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Journal of Medical Case Reports

ISSN: 1752-1947

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