Articles

Pancreatic carcinoma underlying a complex presentation in late pregnancy: a case report

Gestational diabetes mellitus is strongly related to the risk of pancreatic cancer in pregnant women, but gestational diabetes can precede a diagnosis of pancreatic cancer by many years. Women with a history o...

Authors: Ai-Wu Shi, Xiao-Feng Shen, Hong-Juan Ding, Yao-Qiu Liu, Li Meng and Bill Kalionis

Acquired partial lipoatrophy as graft-versus-host disease and treatment with metreleptin: two case reports

Acquired partial lipoatrophy has been reported after bone marrow transplantation during childhood; however, no adult cases have previously been reported. We herein report two adult cases of acquired partial li...

Authors: Yusuke Shibata, Atsuko Nakatsuka, Jun Eguchi, Satoshi Miyamoto, Yukari Masuda, Motoharu Awazawa, Akinobu Takaki, Ryuichi Yoshida, Takahito Yagi and Jun Wada

Klebsiella pneumoniae liver abscess: a case report

Liver abscess has formerly been a polymicrobial infection. Currently, liver abscess due to Klebsiella pneumoniae is increasingly reported, predominantly in Southeast Asia for unknown reasons. Liver abscess due to...

Authors: P. N. S. Premathilake, W. K. S. Kularatne, J. P. K. Jayathilake and S. D. N. Senadhira

Idiopathic calcinosis cutis of the scrotum: a case report and review of the literature

Abnormal deposition of calcium in the skin or subcutaneous tissue is termed calcinosis cutis. Idiopathic calcinosis cutis of the scrotum is an uncommon entity. The pathogenesis of idiopathic calcinosis cutis o...

Authors: M. M. Aarif Syed, Aasiya Rajbhandari and Upama Paudel

Epithelioid cell granuloma with caseating necrosis possibly caused by periapical periodontitis: a case report

Epithelioid cell granuloma with caseating necrosis is a typical pathological finding in tuberculosis. While specific inflammation, including that related to tuberculosis, can induce caseating granuloma formati...

Authors: Risa Shimizu, Kae Tanaka, Yu Oikawa, Hirofumi Tomioka, Kou Kayamori, Tohru Ikeda, Takatomo Yoshioka, Arata Ebihara and Hiroyuki Harada

Difficult-to-diagnose diabetes in a patient treated with cyclophosphamide – the contradictory roles of immunosuppressant agents: a case report

Cyclophosphamide may induce autoimmune diabetes through a decrease in suppressor T cells and increase of proinflammatory T helper type 1 response in animal models. In humans, this association is not as clear d...

Authors: Manuel García-Sáenz, Daniel Uribe-Cortés, Claudia Ramírez-Rentería and Aldo Ferreira-Hermosillo

Mitral valve myxoma presenting with transient ischemic attack: a case report and review of the literature

Myxomas account for approximately half of all primary cardiac neoplasms. Most occur in the left atrium and only rarely are attached to the mitral valve, with just over 30 such cases reported in the literature....

Authors: Kendra J. Grubb, Vasa Jevremovic and Edgar G. Chedrawy

Surgical outcome of jejunum-jejunum intussusception secondary to Rapunzel syndrome: a case report

Adult intestinal intussusception is a rare condition caused by the mechanical disruption of bowel motility. A bezoar is defined as indigestible material inside the gastrointestinal tract that develops into a t...

Authors: Martín Adrián Bolívar-Rodríguez, Rodolfo Fierro-López, Adrián Pamanes-Lozano, Marcel Antonio Cazarez-Aguilar, Benny Alonso Osuna-Wong and José Cándido Ortiz-Bojórquez

Giant prolactinoma, germline BRCA1 mutation, and depression: a case report

Giant prolactinomas are very rare pituitary tumors that may exhibit an aggressive behavior and present with a life-threatening condition.

Authors: Rita Bettencourt-Silva, Joana Queirós, Josué Pereira and Davide Carvalho

Correction to: Giant nonfunctioning adrenal tumors: two case reports and review of the literature

In the publication of this article [1], there is an error in the Family Name and Given Name of the authors since these were interchanged.

Authors: George Chatzoulis, Ioannis Passos, Dimitra-Rafailia Bakaloudi, Dimitrios Giannakidis, Alexandros Koumpoulas, Konstantinos Ioannidis, Ioannis Tsifountoudis, Dimitrios Pappas and Panagiotis Spyridopoulos

Perindopril-induced angioedema of the lips and tongue: a case report

Ace inhibitor-induced angioedema, characterized by sudden-onset swelling of the mucous membrane, skin, or both, is a rare occurrence in the Kingdom of Saudi Arabia. Because of its safety and efficacy, perindop...

Authors: Fawaz Abdullah Alharbi, Abdulwahab Awadh Alharthi and Faisal Nuefa Alsaadi

Swept-source optical coherence tomography and optical coherence tomography angiography in acquired toxoplasmic chorioretinitis: a case report

To describe swept-source optical coherence tomography and optical coherence tomography angiography retinal changes in a case of acute toxoplasmic chorioretinitis both at the time of diagnosis and after healing.

Authors: Diego Vezzola, Davide Allegrini, Alfredo Borgia, Paolo Fogagnolo, Luca Mario Rossetti, Mario R. Romano and Stefano De Cillà

Optic neuritis as the initial clinical presentation of limbic encephalitis: a case report

Limbic encephalitis is characterized by rapid onset of working memory deficit, mood changes, and often seizures. The condition has a strong paraneoplastic association, but not all cases are invariably due to t...

Authors: Stephanie S. L. Cheung, Gary K. K. Lau, Koon-Ho Chan, Ian Y. H. Wong, Jimmy S. M. Lai, Wai Kiu Tang and Kendrick C. Shih

Optic neuritis following diphtheria, tetanus, pertussis, and inactivated poliovirus combined vaccination: a case report

Diphtheria, tetanus, pertussis, and inactivated poliovirus combined vaccine is widely used in young children as part of a series of immunizations before they start attending school. Case studies of demyelinati...

Authors: Preston O’Brien and Robert W. Wong

Pallister–Hall syndrome with orofacial narrowing and tethered cord: a case report

Pallister–Hall syndrome is a rare, autosomal dominant, genetic disorder characterized by different congenital abnormalities: hypothalamic hamartoblastoma, bifid or shortened epiglottis, polydactyly, renal anom...

Authors: Femia Hayek

A family with PTEN mutations with malignancy and an unusually high number of offspring with autism spectrum disorder: a case report

Cowden’s syndrome (OMIM:158350), a rare genetic disorder (incidence ~ 1:250,000), is caused by mutations of the tumor suppressor gene PTEN. In this report, we describe clinical manifestations of a 56-year-old pat...

Authors: Sabrina L. Gruhl, Pankaj Sharma and Thang S. Han

Innominate artery bifurcation pseudoaneurysm repair by “kissing stent-grafts technique”: a case report

We introduce the “kissing stent-grafts technique” for a patient who suffered from a pseudoaneurysm in bifurcation of innominate artery. This technique repaired an innominate artery bifurcation pseudoaneurysm; ...

Authors: Xin Li, Chang Shu, Quan Ming Li, Kun Fang, Ming Li and Wenwu Cai

Case reports: old-timers and evergreens

Authors: C. A. Koch and T. Fülöp

Chylothorax after hepatectomy: a case report

Chylothorax is the accumulation of chyle within the pleural space. Chylothorax can occur as a complication after multiple different types of surgery, most frequently after thoracic surgery, albeit with an inci...

Authors: Ryusei Yamamoto, Yasuji Mokuno, Hideo Matsubara, Hirokazu Kaneko, Yozo Sato and Shinsuke Iyomasa

Activity of cabozantinib in radioresistant brain metastases from renal cell carcinoma: two case reports

Renal cell carcinoma represents 3–5% of adult malignant tumors. Metastases are found in 30–40% of patients and brain metastases occurred in more than 10% of them. Despite significant progress in medical treatm...

Authors: Sylvie Négrier, Guillaume Moriceau, Valéry Attignon, Véronique Haddad, Daniel Pissaloux, Nicole Guerin and Christian Carrie

Surgical repair of partial anomalous pulmonary venous return with intact atrial septum in a 65-year-old woman: a case report

Partial anomalous pulmonary venous return is a rare congenital cardiac anomaly that usually involves the right pulmonary vein and an atrial septal defect. Isolated partial anomalous pulmonary venous return wit...

Authors: Narihiro Ishida, Katsuya Shimabukuro, Shojiro Yamaguchi, Etsuji Umeda, Hiroki Ogura, Shohei Mitta, Ryutaro Kimata, Hirofumi Takemura and Kiyoshi Doi

Early surgical management of traumatic dislocation of the tibialis posterior tendon: a case report and review of the literature

Traumatic dislocation of the tibialis posterior tendon at the ankle is a rare injury. Some of these cases are misdiagnosed as ankle sprains and are not treated properly. In addition, because the conservative t...

Authors: Yuzuru Sakakibara, Hideji Kura, Atsushi Teramoto and Toshihiko Yamashita

Streptococcus pyogenes bacteremia and toxic shock syndrome related to Strongyloides stercoralis hyperinfection: a case report

We describe a patient with Strongyloides stercoralis hyperinfection associated with Streptococcus pyogenes and with streptococcal toxic shock syndrome. To the best of our knowledge this association has not been p...

Authors: Regev Cohen, Talya Finn, Frida Babushkin, Maurice Shapiro, Martina Uda and Tamar Grossman

Reversible dilated cardiomyopathy as a complication of adrenal cortex insufficiency: a case report

Cardiovascular manifestations associated with Addison’s disease are previously documented. We described a case of an 11-year-old girl who developed dilated cardiomyopathy as a complication to Addison’s disease...

Authors: Mohammad Alkhateeb, Mohammad Alsakkal, Mohammad Nour Alfauri and Diana Alasmar

Detection of Asherman’s syndrome after conservative management of placenta accreta: a case report

We present a case involving conservative treatment of placenta accreta, with a subsequent diagnosis of Asherman’s syndrome.

Authors: Kenro Chikazawa, Ken Imai, Wang Liangcheng, Shigetane Sasaki, Isao Horiuchi, Tomoyuki Kuwata and Kenjiro Takagi

Posterior interosseous nerve palsy caused by synovial osteochondromatosis of the elbow analyzed by three-dimensional reconstruction: a case report

Synovial osteochondromatosis, a benign tumor consisting of cartilage and bone, generally presents as multiple osteochondral or chondral nodules. Peripheral nerve palsy caused by synovial osteochondromatosis is...

Authors: Koichi Yano, Yasunori Kaneshiro, Kosuke Sasaki and Hideki Sakanaka

Hypothalamic hypopituitarism secondary to suprasellar metastases from small cell lung cancer: a case report and review of the literature

Metastasis to the pituitary gland is an infrequent clinical problem, and the symptoms caused by metastases have been reported in only 2.5–18.2% of the cases. However, metastasis to the suprasellar lesion has r...

Authors: Ryohei Ono, Ryoji Ito, Keiko Nakagawa, Shinichi Teshima, Izumi Kitagawa and Hideyasu Sugimoto

Cerebellar large B-cell lymphoma: a case report

Primary central nervous system lymphoma is a rare, malignant non-Hodgkin lymphoma that can arise in the brain, spinal cord, eye, leptomeninges, or cranial nerves. Primary central nervous system lymphoma is rar...

Authors: Malik Ghannam, Shaden Mansour, Fareed Jumah, Brent Berry and Albertine Beard

Anterior chamber fibrinoid syndrome after cataract extraction in a patient on ibrutinib for B-cell chronic lymphocytic leukemia: a case report and review of the literature

Ibrutinib is a tyrosine kinase inhibitor commonly used in patients with chronic lymphocytic leukemia. Based on the published literature, it has a very sound ophthalmologic safety profile. In the following, we ...

Authors: Anton M. Kolomeyer, Christopher K. Hwang and Benjamin J. Kim

Ring chromosome 15 – cytogenetics and mapping arrays: a case report and review of the literature

Ring chromosome 15 has been associated in previous studies with different clinical characteristic such as cardiac problems, digit and musculoskeletal abnormalities, and mental and motor problems among others. ...

Authors: César Paz-y-Miño, Jaime Guevara-Aguirre, Ariane Paz-y-Miño, Francesca Velarde, Isaac Armendáriz-Castillo, Verónica Yumiceba, Jesús María Hernández, Juan Luis García and Paola E. Leone

Port site parasitic leiomyoma after laparoscopic myomectomy: a case report and review of the literature

Uterine fibroids are the commonest benign gynecological tumors. Laparoscopic myomectomy is becoming increasingly popular as one of the surgical treatment options for symptomatic cases. Large tissues such as le...

Authors: Felix Mwembi Oindi, Steve Kyende Mutiso and Timona Obura

An atypical presentation of an ovarian lymphoma: a case report

Ovarian lymphoma has a varied clinical presentation and rarely presents with heavy menstrual bleeding. It may occur de novo or secondary to systemic disease and macroscopically appear as solid ovarian tumors.

Authors: Chanil Deshan Ekanayake, Ramani Punchihewa and Prasantha Sudehana Wijesinghe

An unusual presentation of metastatic malignant melanoma causing jejuno-jejunal intussusception: a case report

Small bowel intussusception in adults is rarely encountered. In most cases small bowel intussusception is caused by benign neoplastic lesions, but metastasis of cutaneous malignant melanoma causing small bowel...

Authors: Mihajlo Đokić, David Badovinac, Miha Petrič and Blaž Trotovšek

Congenital intrahepatic portocaval shunts and hypoglycemia due to secondary hyperinsulinism: a case report and review of the literature

Congenital portosystemic shunts present with various associated complications, such as other congenital malformations, hyperammonemia, or hepatopulmonary syndrome. Few cases of associated hypoglycemia have bee...

Authors: Alexander Weigert, Jeanette Bierwolf, Heiko Reutter, Ulrich Gembruch, Joachim Woelfle, Rainer Ganschow and Andreas Mueller

Giant nonfunctioning adrenal tumors: two case reports and review of the literature

There are an estimated 1–2 cases per million per year of adrenocortical carcinoma in the USA. It represents a rare and aggressive malignancy; it is the second most aggressive endocrine malignant disease after ...

Authors: George Chatzoulis, Ioannis Passos, Dimitra-Rafailia Bakaloudi, Dimitrios Giannakidis, Alexandros Koumpoulas, Konstantinos Ioannidis, Ioannis Tsifountoudis, Dimitrios Pappas and Panagiotis Spyridopoulos

Synovial sarcoma of the brachial plexus – a rare tumor in a rare area: a case report

Synovial cell sarcomas are usually seen in a juxta-articular location. However, they occur rarely in the head and neck region.

Authors: Sreekanth Raveendran, Albert Abhinay Kota, Edwin Stephen, Samuel C. R. Pallapati and Binu Prathap Thomas

Reversible dilative cardiomyopathy after electrical injury: a case report

Dilative cardiomyopathy is an uncommon cardiac complication of electric shock.

Authors: Eirini Liodaki, Virginia Galati, Martin Bethge, Wolfgang Göpel, Peter Mailaender and Felix Stang

Tuberculous coxitis with trochanteric bursitis manifesting a year after immigration to Germany: a case report

Osteoarticular tuberculosis is rare in Germany. In particular, trochanteric bursitis is an extremely rare manifestation of osteoarticular tuberculosis. We describe a case of tuberculous coxitis with trochanter...

Authors: Georgios Sogkas, Anna Holz, Elke Riechers, Florian Länger, Christian von Falck, Reinhold Ernst Schmidt and Torsten Witte

Unexpected dislocation following accurate total hip arthroplasty caused by excessive hip joint laxity during myasthenic crisis: a case report

Dislocation following total hip arthroplasty is mainly caused by malposition. However, the coexistence of neuromuscular disorders is also considered a risk for dislocation due to excessive hip joint laxity. To...

Authors: Yoshiki Murotani, Yutaka Kuroda, Koji Goto, Toshiyuki Kawai and Shuichi Matsuda

Pulmonary artery embolism by a metal fragment after a booby trap explosion in a combat patient injured in the armed conflict in East Ukraine: a case report and review of the literature

Pulmonary artery embolization due to projectile embolus is a rare complication in combat patients. Such embolization is rare for combat patients in the ongoing armed conflict, in East Ukraine since 2014.

Authors: Igor Khomenko, Ievgen Tsema, Pavlo Shklyarevych, Kyrylo Kravchenko, Victoriia Holinko, Sofiia Nikolaienko, Sergey Shypilov, Oleg Gerasimenko, Andrii Dinets and Vladimir Mishalov

A rare pure embryonal rhabdomyosarcoma of the urinary bladder in an adult successfully managed with neoadjuvant chemotherapy and surgery: a case report

Rhabdomyosarcoma of the urinary bladder in adults is an extremely rare malignant neoplasm that develops from the bladder wall.

Authors: Mustapha Ahsaini, Khalid Ouattar, Hamid Azelmad, Soufiane Mellas, Jallal Eddine Ammari, Mohammed Fadl Tazi, Mohammed Jamal Fassi, Moulay Hassan Farih, Simohammed Sekal and Taoufik Harmouch

Death related to Cedecea lapagei in a soft tissue bullae infection: a case report

Cedecea lapagei bacterium was discovered in 1977 but was not known to be pathogenic to humans until 2006. In the medical literature there are very few clinical case reports of Cedecea lapagei; none have reported ...

Authors: Victor Ramzes Chavez Herrera, Maria Fernanda Rosas De Silva, Homero Orendain Alcaraz, Gabriel Ceja Espiritu, Karla Carrazco Peña and Valery Melnikov

Pulmonary cryptococcosis coexisting with adenocarcinoma: a case report and review of the literature

Pulmonary cryptococcosis is a common fungal infection frequently seen in immunocompromised patients. Owing to its nonspecific clinical and radiographic features, the differential diagnosis with secondary tuber...

Authors: Liyang Li, Liang Zhuang, Jian Zhou and Changzhou Shao

Multidrug-resistant Aeromonas hydrophila causing fatal bilateral necrotizing fasciitis in an immunocompromised patient: a case report

Aeromonas hydrophila is a water-dwelling, gram-negative rod-shaped bacterium, associated with diarrheal illness and, less commonly, necrotizing skin and soft tissue infections, especially among immunocompromised ...

Authors: Alejandra Ugarte-Torres, Sarah Perry, Angela Franko and Deirdre L Church

Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report

Multiple myeloma is a very heterogeneous disease comprising a number of genetic entities that differ from each other in their evolution, mode of presentation, response to therapy, and prognosis. Due to its mor...

Authors: Satoko Oka, Kazuo Ono and Masaharu Nohgawa

Dengue shock syndrome complicated with acute liver failure and kidney injury, infective endocarditis, and deep vein thrombosis: a case report

Dengue fever is a mosquito-borne viral disease with a very high incidence in Southeast Asia. Most patients with dengue fever recover following a self-limiting febrile illness, while a small proportion may prog...

Authors: Keshinie Samarasekara and Janake Munasinghe

Post-mortem diagnosis of Pompe disease by exome sequencing in a Moroccan family: a case report

Pompe disease is an autosomal recessive lysosomal storage disorder characterized by progressive myopathy with proximal muscle weakness, respiratory muscle dysfunction, and cardiomyopathy. Its prevalence ranges...

Authors: Najlae Adadi, Maryem Sahli, Grégory Egéa, Ilham Ratbi, Mohamed Taoudi, Layla Zniber, Wafaa Jdioui, Said El Mouatassim and Abdelaziz Sefiani

Extracorporeal membrane oxygenation in aluminum phosphide poisoning in Nepal: a case report

Aluminum phosphide is a very common suicide agent in developing countries like Nepal. Due to the unavailability of a specific antidote, mortality is very high because the phosphine molecule that is formed lead...

Authors: Achyut Sharma, Apurb Sharma, Anil Acharya, Diptesh Aryal, Bijoy G. Rajbanshi, Prajjwal Raj Bhattarai, Ashim Regmi and Anup Ghimire

Recurrent biliary dissemination of colon cancer liver metastasis: a case report

Most colorectal cancer liver metastases form nodules within the hepatic parenchyma, and hepatectomy is the only radical treatment for synchronous metastases. There is concern about intrabiliary tumor growth wh...

Authors: Ichiro Onishi, Masato Kayahara, Ryohei Takei, Naoki Makita, Masayoshi Munemoto, Yasumichi Yagi and Atsuhiro Kawashima

Poland syndrome accompanied by internal iliac artery supply disruption sequence: a case report

Poland syndrome is a congenital malformation characterized by ipsilateral hand and chest wall depression, including an absence or hypoplasia of the breast and pectoral muscles. These hypoplastic defects are re...

Authors: Kenji Gonda, Yosuke Tachiya, Yuichi Hatakeyama, Tomoyuki Momma, Tomoko Tamaoki, Yuko Maejima, Yuichi Rokkaku, Shigehira Saji, Kenju Shimomura and Koji Kono