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  1. Severe acute respiratory syndrome coronavirus 2 infection can lead to a constellation of viral and immune symptoms called coronavirus disease 2019. Emerging literature increasingly supports the premise that se...

    Authors: Artem Minalyan, Franklin L. Thelmo, Vincent Chan, Stephanie Tzarnas and Faizan Ahmed

    Citation: Journal of Medical Case Reports 2021 15:112

    Content type: Case report

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  2. Most sudden-onset hearing loss is due to otolaryngologic- and very rarely to cerebrovascular disease. We report a woman with sudden bilateral sensorineural hearing loss. This case suggests that even in the abs...

    Authors: Tomoya Kinouchi, Keisuke Ishitani, Shinichi Uyama, Tadashi Miyamoto, Naomi Fujimoto and Hiromi Ueta

    Citation: Journal of Medical Case Reports 2021 15:111

    Content type: Case report

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  3. Pneumatosis intestinalis (PI) is a rare entity which refers to the presence of gas within the wall of the small bowel or colon which is a radiographic sign. The etiology and clinical presentation are variable....

    Authors: M. C. Martín-Soberón, S. Ruiz, G. De Velasco, R. Yarza, A. Carretero, D. Castellano and J. M. Sepúlveda-Sánchez

    Citation: Journal of Medical Case Reports 2021 15:109

    Content type: Case report

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  4. Dermoid cysts are well-known lesions that manifest as subcutaneous tumors around the lateral sides of the eyebrows in young patients. Computed tomography or magnetic resonance imaging (MRI) is often performed ...

    Authors: Taro Mikami, Chie Maeda, Fumihiko Aoki, Toshinori Iwai, Yuichiro Yabuki, Tetsuhiko Okabe, Kenichi Ohashi and Jiro Maegawa

    Citation: Journal of Medical Case Reports 2021 15:99

    Content type: Case report

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  5. Pregnancy seems to increase the risk of thrombotic thrombocytopenic purpura (TTP) relapses and make the TTP more severe in any of the pregnancy trimesters, or even during the postpartum period.

    Authors: Soheila Aminimoghaddam, Narjes Afrooz, Setare Nasiri, Ozra Motaghi Nejad and Fatemeh Mahmoudzadeh

    Citation: Journal of Medical Case Reports 2021 15:104

    Content type: Case report

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  6. Hemophagocytic lymphohistiocytosis (HLH) is characterized by hyperinflammation and life-threatening cytopenias. Survival is poor, and management is pivotal on rapid identification of the disease. HLH is associ...

    Authors: Y. Sun, C. Blieden, B. Y. Merritt, R. Sosa and Gustavo Rivero

    Citation: Journal of Medical Case Reports 2021 15:98

    Content type: Case report

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  7. Lichen planus is a rare autoimmune disease primarily affecting the skin and mucous membranes of the oral mucosa, vulva, and vagina. Diagnosis is difficult and often delayed as the clinicians do not associate t...

    Authors: Lajya Devi Goyal, Priyanka Garg and Manmeet Kaur

    Citation: Journal of Medical Case Reports 2021 15:97

    Content type: Case report

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  8. We report a high-risk case of a coronavirus disease 19 (COVID-19)-positive patient with comorbidities including diabetes mellitus (DM), hypertension (HTN), hypothyroidism and chronic kidney disease (CKD), trea...

    Authors: Alka Mishra, Sumitra A. Bentur, Sonika Thakral, Rahul Garg and Bhanu Duggal

    Citation: Journal of Medical Case Reports 2021 15:95

    Content type: Case report

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  9. Arthritis is rarely reported as a paraneoplastic manifestation of occult malignancy. We report herein two cases of paraneoplastic arthritis due to occult malignancy.

    Authors: Benjamin Sachdev Manjit Singh, Sharifah Aishah Wan, Yaw Kiet Cheong, Seow Lin Chuah, Cheng Lay Teh and Ahmad Tirmizi Jobli

    Citation: Journal of Medical Case Reports 2021 15:94

    Content type: Case report

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  10. Current management of choledocholithiasis entails the use of endoscopic retrograde cholangiopancreatography (ERCP) and clearance of the common bile duct. A rare complication of this procedure is the impaction ...

    Authors: Ibrahim Abu Shakra, Maxim Bez, Amitai Bickel, Mahran Badran, Fahed Merei, Samer Ganam, Walid Kassis and Eli Kakiashvili

    Citation: Journal of Medical Case Reports 2021 15:93

    Content type: Case report

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  11. The risk of stroke after carotid sinus massage is greater if there is preexisting carotid stenosis or carotid plaques. We present the case of a patient with underlying 40% carotid stenosis, who developed a wat...

    Authors: Edgar R. Lopez-Navarro, Götz Greif, Carl-Albrecht Haensch, Adrian Ringelstein and Robert Larbig

    Citation: Journal of Medical Case Reports 2021 15:83

    Content type: Case report

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  12. The double-duct sign is defined as dilation of both the common bile duct and pancreatic duct, which usually indicates pancreatic malignancy. However, benign causes have also been reported to cause a double-duc...

    Authors: Naseem Al-Khoury, Okbah Mohamad, Abd Al-Jawad Mazloum and Maher Madi

    Citation: Journal of Medical Case Reports 2021 15:82

    Content type: Case report

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  13. An infected aortic aneurysm is a rare and life-threatening vascular condition with a high incidence of arterial rupture and recurrence even after treatment. One of the most common causes of an infected aortic ...

    Authors: Kiyoshi Takemoto, Michitaka Nakamura, Masaaki Sakuraya, Tomonori Yamamoto, Wataru Iwanaga, Kazuaki Atagi, Kazuo Yamanaka and Takeshi Matsuyama

    Citation: Journal of Medical Case Reports 2021 15:81

    Content type: Case report

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  14. Breast tuberculosis is a rare disease, even in endemic areas. The diagnosis can be challenging, as it can mimic breast cancer. We aim to report our experience and discuss diagnoses and management modalities.

    Authors: M. Ghalleb, S. Seghaier, O. Adouni, H. Bouaziz, A. Bouida, J. Ben Hassouna, R. Chargui and K. Rahal

    Citation: Journal of Medical Case Reports 2021 15:73

    Content type: Case report

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  15. Primary urethral carcinoma (PUC) is rare and accounts for < 1% of all genito-urinary cancers. There is a male predominance of 3:1 and a peak incidence in the 7th and 8th decades. The aetiology of this cancer i...

    Authors: Emily Walsh, Niall Kelly, Padraig Daly, Nigam Shah and Ivor Cullen

    Citation: Journal of Medical Case Reports 2021 15:91

    Content type: Case report

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  16. Very little is known about the risk that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral infection poses to cancer patients, many of whom are immune compromised causing them to be more susce...

    Authors: D. Madduri, S. Parekh, T. B. Campbell, F. Neumann, F. Petrocca and S. Jagannath

    Citation: Journal of Medical Case Reports 2021 15:90

    Content type: Case report

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  17. Tumor molecular screening allows categorization of molecular alterations to select the best therapeutic strategy. AT-rich interactive domain-containing 1A (ARID1A) gene mutations are present in gastric, endometri...

    Authors: Mercedes Durán, Iris Faull, Enrique Lastra, Jean-Francois Laes, Ana Belén Rodrigo and Ricardo Sánchez-Escribano

    Citation: Journal of Medical Case Reports 2021 15:89

    Content type: Case report

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  18. Mood and anxiety disorders are common in women of childbearing age, especially during the peripartum period. As more women seek medical management for these conditions, there is an increasing need for studies ...

    Authors: Greg J. Marchand, Katerina Meassick, Hannah Wolf, Sophia K. Hopewell, Katelyn Sainz, Sienna M. Anderson, Kelly Ware, Janelle Vallejo, Alexa King, Stacy Ruther, Giovanna Brazil, Kaitlynne Cieminski and Nicolas Calteux

    Citation: Journal of Medical Case Reports 2021 15:88

    Content type: Case report

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  19. Combination regimens that include immune checkpoint (ICI) and vascular endothelial growth factor (VEGF) inhibition have opened the door to new treatment opportunities for patients with metastatic renal cell ca...

    Authors: T. Anders Olsen, Dylan J. Martini, Sean T. Evans, Jamie M. Goldman and Mehmet Asim Bilen

    Citation: Journal of Medical Case Reports 2021 15:72

    Content type: Case report

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  20. Coronavirus disease 2019 (COVID-19), the global pandemic that has spread throughout the world, is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Given the limited scientific evidence o...

    Authors: Maryam Rabiei, Tahereh Soori, Amene Abiri, Zohreh Farsi, Arshia Shizarpour and Reihaneh Pirjani

    Citation: Journal of Medical Case Reports 2021 15:87

    Content type: Case report

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  21. Myelomeningocele, which causes a neurogenic bladder, is usually treated with anticholinergics in children with neurogenic detrusor overactivity (NDO); however, anticholinergics cause side effects such as dry m...

    Authors: Taiki Kato, Kentaro Mizuno, Hidenori Nishio, Takahiro Yasui and Yutaro Hayashi

    Citation: Journal of Medical Case Reports 2021 15:86

    Content type: Case report

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  22. Wound healing is a complex and dynamic process. Healing of acute and chronic wounds can be impaired by patient factors (that is, comorbidities) and/or wound factors (that is, infection). Regenerative medicine ...

    Authors: Vincenzo Davide Palumbo, Stefano Rizzuto, Giuseppe Damiano, Salvatore Fazzotta, Andrea Gottardo, Giuseppina Mazzola and Attilio Ignazio Lo Monte

    Citation: Journal of Medical Case Reports 2021 15:85

    Content type: Case report

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  23. Turner syndrome is a genetic disorder in females and is the result of complete or partial loss of an X chromosome during fertilization. The missing X chromosome is originally either from the mother's ovum or t...

    Authors: Seyedetahere Mousavi, Batool Amiri, Saidee Beigi and Mohammadreza Farzaneh

    Citation: Journal of Medical Case Reports 2021 15:79

    Content type: Case report

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  24. Bronchial fistula is a severe complication of pneumonectomy with a high mortality rate. We previously reported a technique for bronchial closure to prevent bronchial fistula in a canine model. We described tha...

    Authors: Kimitaka Makidono, Yoshihiro Miyata, Takuhiro Ikeda, Yasuhiro Tsutani, Yuichiro Kai, Kei Kushitani, Yukio Takeshima and Morihito Okada

    Citation: Journal of Medical Case Reports 2021 15:71

    Content type: Case report

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  25. Hereditary hemochromatosis is an autosomal recessive disorder where the clinical phenotype of skin pigmentation and organ damage occurs only in homozygotes. Simple heterozygotes, that is, just C282Y, typically...

    Authors: Venkatachalam Shobi, Awe Adeseye, Ballard Billy and Kalliny Medhat

    Citation: Journal of Medical Case Reports 2021 15:84

    Content type: Case report

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  26. Lichen simplex chronicus has been defined as a localized skin condition characterized by thickening, hyperpigmentation and accentuated skin markings from chronic itching and from repeated scratching. The affec...

    Authors: Ozzy M. Emmanuel, Ana V. Karovska and Okey Ikedilo

    Citation: Journal of Medical Case Reports 2021 15:80

    Content type: Case report

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  27. Accurate diagnosis of metastatic tumors in the breast is crucial because the therapeutic approach is essentially different from primary tumors. A key morphological feature of metastatic tumors is their lack of...

    Authors: Yurina Maeshima, Tomo Osako, Hidetomo Morizono, Mayu Yunokawa, Yumi Miyagi, Mari Kikuchi, Takayuki Ueno, Shinji Ohno and Futoshi Akiyama

    Citation: Journal of Medical Case Reports 2021 15:78

    Content type: Case report

    Published on:

  28. Retiform Hemangioendothelioma (RH) is an extremely rare vascular tumor of intermediate biological behavior, which is prone to local recurrence but rarely shows metastasis to distant sites. It may harbor areas ...

    Authors: Qurratulain Chundriger, Muhammad Usman Tariq, Shabina Rahim, Jamshid Abdul-Ghafar and Nasir Ud Din

    Citation: Journal of Medical Case Reports 2021 15:69

    Content type: Research article

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  29. Rapid intravenous administration of vancomycin may manifest with histaminergic responses with clinical features ranging from mild rashes, pruritus and even shock. This case reports of a child, who was accident...

    Authors: Sharad Khakurel and Sangam Rawal

    Citation: Journal of Medical Case Reports 2021 15:77

    Content type: Case report

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  30. Myeloproliferative neoplasms (MPNs) such as polycythemia Vera (PV) and Essential Thrombocythemia (ET) can be associated with a high risk of both venous and arterial thrombosis. However, the co-existence betwee...

    Authors: Rime Benmalek, Hanane Mechal, Hatim Zahidi, Karim Mounaouir, Salim Arous, Mohamed El Ghali Benouna, Abdenasser Drighil and Rachida Habbal

    Citation: Journal of Medical Case Reports 2021 15:76

    Content type: Case report

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  31. Glycogen storage disease (GSD) type Ia is a glycogenesis disorder with long-term complications such as hepatomegaly and renal dysfunction and is caused by congenital loss of glucose-6-phosphatase (G6Pase) expr...

    Authors: Daisuke Katayama, Hiroo Baba, Takashige Kuwabara, Jun Kido, Hiroshi Mitsubuchi, Shirou Matsumoto and Kimitoshi Nakamura

    Citation: Journal of Medical Case Reports 2021 15:75

    Content type: Case report

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  32. Bertolotti’s syndrome is widely known to cause low back pain in young patients and must be considered as a differential diagnosis. Its treatment such as conservative therapy or surgery remains controversial. S...

    Authors: Kensuke Shinonara, Michiya Kaneko, Ryo Ugawa, Shinya Arataki and Kazuhiro Takeuchi

    Citation: Journal of Medical Case Reports 2021 15:68

    Content type: Case report

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  33. Acquired hemophilia A is a rare coagulopathy caused by inhibitors of blood coagulation factor VIII. Patients with acquired hemophilia A have a higher mortality risk (5–10%) than those with congenital hemophili...

    Authors: Keigo Maeda, Shinsuke Yamamoto, Naoki Taniike and Toshihiko Takenobu

    Citation: Journal of Medical Case Reports 2021 15:66

    Content type: Case report

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  34. Euglycemic diabetic ketoacidosis is an uncommon but life-threatening complication associated with the use of sodium-glucose cotransporter 2 inhibitors that causes lower than expected blood glucose levels typic...

    Authors: Brian Vadasz, Mattan Arazi, Yousef Shukha, Ofir Koren and Riad Taher

    Citation: Journal of Medical Case Reports 2021 15:62

    Content type: Case report

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  35. Muscular variations are potentially symptomatic and may complicate imaging interpretation. Intrinsic foot musculature and extrinsic tendon insertion variations are common. Distinct supernumerary muscles are ra...

    Authors: R. Claire Aland and Alana C. Sharp

    Citation: Journal of Medical Case Reports 2021 15:58

    Content type: Case report

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  36. Ventral incisional hernia is a common problem after abdominal surgery. Most patients with these hernias present with greater omentum and gastrointestinal prolapse. However, hepatic herniation through a ventral...

    Authors: Toshihiro Misumi, Masahiro Nishihara, Keizo Sugino and Yukari Kawasaki

    Citation: Journal of Medical Case Reports 2021 15:56

    Content type: Case report

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  37. Vaping-associated lung injury is a newly emerging disease process with the potential for serious health implications and high mortality, even despite the lack of underlying lung disease. We present a case of a...

    Authors: Anthony Lucero, Niklas Eriksson, Carli Nichta and Kimberly Sokol

    Citation: Journal of Medical Case Reports 2021 15:70

    Content type: Case report

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  38. Hyperkalemia and acute coronary syndrome are not only all responsible for syncope related to complete atrioventricular block, but also share parts of electrocardiogram manifestations. Additionally, they influe...

    Authors: Miaomiao Cao, Li Chen, Chaofeng Sun and Guoliang Li

    Citation: Journal of Medical Case Reports 2021 15:55

    Content type: Case report

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  39. Pilonidal sinus is commonly seen at the sacrococcygeal region and few other sites, usually located at the midline, at areas where hairs collect or near protuberances or some adjacent rubbing surfaces. Its pres...

    Authors: B. N. Adhikari, S. Khatiwada and A. Bhattarai

    Citation: Journal of Medical Case Reports 2021 15:64

    Content type: Case report

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  40. Cirrhosis-associated portal vein thrombosis (CA-PVT) has been reportedly observed in 5–30% of cirrhotic patients. Moreover, the acute exacerbation of CA-PVT is likely to occur after certain situations, such as...

    Authors: Junya Toyoda, Daisuke Morioka, Nobutoshi Horii, Gakuryu Nakayama, Norio Oyama, Fumio Asano, Yusuke Izumisawa, Masaru Miura, Yoshiki Sato and Itaru Endo

    Citation: Journal of Medical Case Reports 2021 15:52

    Content type: Case report

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  41. Rehabilitation of the entire dentition with amelogenesis imperfecta (AI) tends to pose a great challenge to the clinician. Most of the cases of amelogenesis imperfecta are reported to be associated with skelet...

    Authors: M. Roma, Puneet Hegde, M. Durga Nandhini and Shreya Hegde

    Citation: Journal of Medical Case Reports 2021 15:67

    Content type: Research article

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  42. Intoxication with Patent Blue V [sodium compound of (diethylamino-4-phenyl)(hydroxy-5-disulfo-2,4-phenyl) methanol] can lead to high levels of methemoglobin and metabolic acidosis. In severe cases and if not r...

    Authors: Fabio Silvio Taccone, Mickael Gardette, Jacques Creteur, Alexandre Brasseur, Sophie Lorent and David Grimaldi

    Citation: Journal of Medical Case Reports 2021 15:63

    Content type: Case report

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  43. Cardiac stress testing is a validated diagnostic tool to assess symptomatic patients with intermediate pretest probability of coronary artery disease (CAD). However, in some cases, the cardiac stress test may ...

    Authors: Mishita Goel, Shubhkarman Dhillon, Sarwan Kumar and Vesna Tegeltija

    Citation: Journal of Medical Case Reports 2021 15:49

    Content type: Case report

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  44. The coronavirus disease 2019 (COVID-19) pandemic has caused irreparable damage to society, and the damage continues. Pediatricians are confronted with COVID-19 in a variety of presentations, which may lead to...

    Authors: Marjan Tariverdi, Nazanin Farahbakhsh, Hamed Gouklani, Fatemeh Khosravifar and Mohammad Tamaddondar

    Citation: Journal of Medical Case Reports 2021 15:65

    Content type: Case report

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