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  1. Droxidopa is an oral treatment for the stepwise treatment of neurogenic orthostatic hypotension from autonomic dysfunction. It has been shown to be useful predominantly with neurogenic orthostatic hypotension ...

    Authors: Annie H. Ho, Christopher W. Kinter, John Wight, Anudeep R. Neelam and David Krakow

    Citation: Journal of Medical Case Reports 2020 14:73

    Content type: Case report

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  2. Sacrococcygeal teratoma is one of the most frequently prenatally diagnosed neoplasias. Obstetric ultrasound has a role in the diagnosis and management of these tumors during pregnancy. In this report, we descr...

    Authors: Anna Moreno Baró, Silvia Pina Perez, Montserrat Mestre Costa, Cristina Lesmes Heredia, Laura Serra Azuara, Judith Lleberia Juanos and Marc Zamora Lapiedra

    Citation: Journal of Medical Case Reports 2020 14:72

    Content type: Case report

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  3. Hantavirus infection is an emerging zoonotic infection which has two characteristic patterns of presentation: hantavirus pulmonary syndrome and hemorrhagic fever with renal syndrome. The clinical presentation ...

    Authors: Chamara Dalugama, Madushi Nanayakkara, Nimanthi Rathnayaka and Arjuna Medagama

    Citation: Journal of Medical Case Reports 2020 14:71

    Content type: Case report

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  4. Ocular allergy is a common disease, especially in the pediatric population, with unpleasant and long-term consequences, including corneal complications and decreased visual acuity. This study reports two cases...

    Authors: Ricardo Alexandre Stock, Silvia Letícia Teixeira Lazzari, Isadora Proner Martins and Elcio Luiz Bonamigo

    Citation: Journal of Medical Case Reports 2020 14:70

    Content type: Case report

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  5. The mortality rate is very high for patients with severe multiple trauma with massive pulmonary contusion containing intrapulmonary hemorrhage. Multiple treatment modalities are needed not only for a preventio...

    Authors: Futoshi Nagashima, Satoshi Inoue and Miho Ohta

    Citation: Journal of Medical Case Reports 2020 14:69

    Content type: Case report

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  6. Breast cancer is the most common cancer in women. However, in the management of breast cancer, paraneoplastic neurological syndromes represent a diagnostic and therapeutic challenge. The diagnosis of paraneopl...

    Authors: Giuseppe Sena, Gaetano Gallo, Giuseppina Vescio, Denise Gambardella, Stefano de Franciscis and Mariuccia Renne

    Citation: Journal of Medical Case Reports 2020 14:67

    Content type: Case report

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  7. Cystic echinococcosis is a zoonotic infection caused by Echinococcus granulosus. This case report shows the difficulty in differential diagnosis in a patient with highly suspected hydatid disease.

    Authors: Albrecht Boehlig, Valentin Blank, Thomas Karlas, Henning Trawinski, Hans-Michael Hau, Andri Arnosson Lederer and Thomas Berg

    Citation: Journal of Medical Case Reports 2020 14:65

    Content type: Case report

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  8. Pulmonary nodules are a common cause for concern in patients with human immunodeficiency virus and acquired immunodeficiency syndrome. Most commonly, they are the result of an infection, given the patients’ im...

    Authors: Jessica N. Mezzanotte, I-Sanna Gibbons-Fideler, Konstantin Shilo, Mark Lustberg and Srinivas Devarakonda

    Citation: Journal of Medical Case Reports 2020 14:64

    Content type: Case report

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  9. Balantidium coli, a parasitic unicellular ciliate, often causes asymptomatic balantidiasis of the colon, but extraintestinal disease may occur rarely in immunosuppressed individuals. Renal balantidiasis associate...

    Authors: Pongsakorn Martviset, Kridsada Sirisabhabhorn, Supaporn Pumpa, Pochong Rhongbutsri, Aree Taylor and Walter R. J. Taylor

    Citation: Journal of Medical Case Reports 2020 14:63

    Content type: Case report

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  10. Combination therapy of interferon and ribavirin has traditionally been used to eradicate hepatitis C virus. The sustained virologic response achieved with interferon-related therapy is persistent, and late rel...

    Authors: Ken Kurokawa, Takamasa Ohki, Jun Kato, Yukiyo Fukumura, Makoto Imai, Chikako Shibata, Junya Arai, Mayuko Kondo, Kaoru Takagi, Kentaro Kojima, Michiharu Seki, Masaya Mori, Nobuo Toda and Kazumi Tagawa

    Citation: Journal of Medical Case Reports 2020 14:62

    Content type: Case report

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  11. Although gastrointestinal involvement is the most common site for extra-genital endometriosis, deep infiltrative endometriosis, which affects the mucosal layer, is very rare.

    Authors: Joshua J. Keith, Lorenzo O. Hernandez, Livia Y. Maruoka Nishi, Tarang P. Jethwa, Jason T. Lewis and George G. A. Pujalte

    Citation: Journal of Medical Case Reports 2020 14:61

    Content type: Case report

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  12. The palmaris longus muscle is considered one of the most anatomically variable muscles in the human body. Localized swelling of the forearm due to hypertrophy of the palmaris longus muscle is rare.

    Authors: Majdi Hashem, Raheef Alatassi, Kaushal Narinder and Fawaz Emran

    Citation: Journal of Medical Case Reports 2020 14:60

    Content type: Case report

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  13. The coexistence of two morphologically different tumors attached to each other creates a very rare type of tumor called a collision tumor. Collision tumors containing pituitary adenoma–sellar meningioma have o...

    Authors: Emre Gezer, Zeynep Cantürk, Alev Selek, Berrin Çetinarslan, İlhan Tarkun, Mehmet Sözen, Umay Kiraz, Yeşim Saliha Gürbüz, Savaş Ceylan and Burak Çabuk

    Citation: Journal of Medical Case Reports 2020 14:59

    Content type: Case report

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  14. Long-term infertility can be attributed to many factors, with the genetic factor being the most overlooked due to its many nonspecific morphological or endocrine signs. We present a rare case of a patient with...

    Authors: Mohammad Marwan Alhalabi and Marwan Alhalabi

    Citation: Journal of Medical Case Reports 2020 14:58

    Content type: Case report

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  15. Given the absence of consensus diagnostic criteria for giant cell arteritis, clinicians may encounter difficulty with identification of new-onset headache in patients older than age 50 years presenting with vi...

    Authors: Matthew J. Samec, Andres G. Madrigal, Charlotte H. Rydberg and Matthew J. Koster

    Citation: Journal of Medical Case Reports 2020 14:57

    Content type: Case report

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  16. Neurofibromatosis type 1 is characterized by multiple café au lait spots and cutaneous and plexiform neurofibromas, and is one of the most common autosomal dominant hereditary disorders caused by mutations of ...

    Authors: Takahiko Obo, Nobuyuki Koriyama, Akinori Tokito, Kazuma Ogiso and Yoshihiko Nishio

    Citation: Journal of Medical Case Reports 2020 14:56

    Content type: Case report

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  17. Multiple myeloma has witnessed significant advances due to the approval of many novel agents. However, in spite of all these new developments, multiple myeloma remains an incurable disease with inevitable rela...

    Authors: Khadega A. Abuelgasim, Noha Alherz, Ayman Alhejazi and Moussab Damlaj

    Citation: Journal of Medical Case Reports 2020 14:54

    Content type: Case report

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  18. Disseminated intravascular coagulation is a critical complication of advanced clear cell renal cell carcinoma, despite the rarity of the occurrence of disseminated intravascular coagulation in such tumors. The...

    Authors: Huy Le Trinh, Vuong Thi Nguyen, Ngan Kim Mai, Bach Trung Tran and Quynh Nga Pham

    Citation: Journal of Medical Case Reports 2020 14:52

    Content type: Case report

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  19. Osteosarcoma is a common malignancy of bone that usually occurs in individuals in the age range of 0–24 years. Extraskeletal osteosarcoma is a rare tumor presentation which originates in non-bony tissues. Extr...

    Authors: Ramin Saadaat, Jamshid Abdul-Ghafar, Nasir Ud Din and Ahmed Maseh Haidary

    Citation: Journal of Medical Case Reports 2020 14:51

    Content type: Case report

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  20. Melioidosis is a potentially fatal bacterial infection caused by Burkholderia pseudomallei. The existence of melioidosis in Sri Lanka was once unheard of, and entertaining it as a diagnosis in clinical practice w...

    Authors: Manoji M. K. Pathirage, Senanayake A. M. Kularatne and Kosala G. Weerakoon

    Citation: Journal of Medical Case Reports 2020 14:50

    Content type: Case report

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  21. The increasing incidence of allergies and allergic reactions among children and adults has become a major public health concern. The etiology of allergic reactions can often be confirmed based on a detailed hi...

    Authors: Sarah Green, Allison Hicks, Chelsea Hilsendager, Maureen Bauer and Guido K. W. Frank

    Citation: Journal of Medical Case Reports 2020 14:49

    Content type: Case report

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  22. Lyme disease is the most common tick-borne illness in the USA, Canada, and Europe. Clinical manifestations vary greatly, with localized skin findings functioning as early signs of the disease, followed by diss...

    Authors: Allison Remiker, David Haslam and Theodosia A. Kalfa

    Citation: Journal of Medical Case Reports 2020 14:48

    Content type: Case report

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  23. Hydralazine is a common vasodilator which has been used for the treatment of hypertension and heart failure. Hydralazine can induce antineutrophil cytoplasmic antibody-associated vasculitis due to its auto-imm...

    Authors: Ahmad Al-Abdouh, Abdul Muhaymin Siyal, Hanan Seid, Ammer Bekele and Pablo Garcia

    Citation: Journal of Medical Case Reports 2020 14:47

    Content type: Case report

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  24. Fasciotomy is a life-saving procedure to treat acute compartment syndrome, a surgical emergency. As fasciotomy dramatically improves wound pain, it should be performed as soon as possible. Moreover, delays in ...

    Authors: Ryo Esumi, Ayumu Yokochi, Motomu Shimaoka and Eiji Kawamoto

    Citation: Journal of Medical Case Reports 2020 14:46

    Content type: Case report

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  25. During embryogenesis, bilateral thickening of ectoderm from anterior axillary folds to inguinal folds, called mammary ridges or milk lines, develops into breast tissues. Only a pair in the pectoral area is spa...

    Authors: Peeradech Thasanabanchong and Mawin Vongsaisuwon

    Citation: Journal of Medical Case Reports 2020 14:45

    Content type: Case report

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  26. Metastatic neuroendocrine carcinoma often presents as carcinoma of unknown primary. Although most cases display immunohistochemical positivity for neuroendocrine markers, subsets of cases display reduced or ne...

    Authors: Carl Christofer Juhlin, Jan Zedenius and Felix Haglund

    Citation: Journal of Medical Case Reports 2020 14:44

    Content type: Case report

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  27. Extranodal natural killer/T cell lymphoma, nasal type, is one of the more common subtypes of mature T cell lymphoma, especially in the Far East Asian population. This aggressive histologic subtype of periphera...

    Authors: Yao-Chung Liu, Ting-An Lin, Hao-Yuan Wang, Po-Shen Ko, Chia-Jen Liu, Liang-Tsai Hsiao, Sheng-Hsuan Chien and Jyh-Pyng Gau

    Citation: Journal of Medical Case Reports 2020 14:43

    Content type: Case report

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  28. Neuroendocrine carcinomas mainly affect the bronchopulmonary and the gastrointestinal systems. Breast localizations are very rare. They represent less than 0.1% of all breast cancers. A definitive diagnosis re...

    Authors: Loubna Hejjane, Karima Oualla, Zineb Bouchbika, Mouna Bourhafour, Anas Lhlou Mimi, Efared Boubacar, Abdellatif Benider, Zineb Benbrahim, Samia Aarifi and Nawef Mellas

    Citation: Journal of Medical Case Reports 2020 14:41

    Content type: Case report

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  29. Vaginal cuff dehiscence is a rare but potentially grave complication after total hysterectomy. Abdominal or pelvic contents are at risk of evisceration through the vaginal opening. It is associated with signif...

    Authors: Ajay Agrawal, Kuan-Gen Huang and Marie Christine Valerie Mendoza

    Citation: Journal of Medical Case Reports 2020 14:40

    Content type: Case report

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  30. Synchronous renal cell carcinoma metastasizing to the pancreas and subcutaneous tissue is very rare. Unusual metastatic sites require attention during follow-up of renal cell carcinoma. It is extremely rare fo...

    Authors: Wenjie Chin, Linping Cao, Xi Liu, Yufu Ye, Yuanxing Liu, Jun Yu and Shusen Zheng

    Citation: Journal of Medical Case Reports 2020 14:36

    Content type: Case report

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  31. Follicular lymphoma is an indolent non-Hodgkin lymphoma that is most commonly diagnosed in elderly individuals. The majority of patients with follicular lymphoma present with advanced disease. Despite the rece...

    Authors: Salma Machan, Carlos Plaza, Yosmar Pérez-González, Maria Rodriguez-Pinilla, Luis Requena and Raul Cordoba

    Citation: Journal of Medical Case Reports 2020 14:35

    Content type: Case report

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  32. Lipodystrophies are a group of diseases which are characterized by abnormal adipose tissue deposition and are frequently associated with metabolic changes. Congenital generalized lipodystrophy is an autosomal ...

    Authors: Vanessa Guerreiro, Irene Bernardes, Josué Pereira, Roberto Pestana Silva, Susana Fernandes, Davide Carvalho and Paula Freitas

    Citation: Journal of Medical Case Reports 2020 14:34

    Content type: Case report

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  33. The prevalence of primary aldosteronism concurrent with subclinical Cushing’s syndrome was higher than previously thought. Through analyzing a rare clinical case, we summarized the diagnosis and management of ...

    Authors: Yingxiao Zhang, Jianyu Tan, Qin Yang, Zhipeng Du, Shumin Yang, Wenwen He, Ying Song, Jinbo Hu, Yi Yang, Qifu Li, Yao Zhang, Yunfeng He and Qingfeng Cheng

    Citation: Journal of Medical Case Reports 2020 14:32

    Content type: Case report

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  34. Papillary breast lesions may be benign, atypical, and malignant lesions. Pathological and clinical differentiation of breast papillomas can be a challenge. Unlike malignant lesions, benign breast papillomas ar...

    Authors: Amit L. Jain, Janice Mullins, Justin R. Smith, Poojitha Valasareddy, Emily Miller, Amina Chaudhry, Julie Ryder, Felicia Hare, Harsha Ranganath, Michael Berry, David Robins, Lee Schwartzberg and Gregory A. Vidal

    Citation: Journal of Medical Case Reports 2020 14:33

    Content type: Case report

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  35. Miller Fisher syndrome is a variant of acute inflammatory demyelinating polyneuropathy classically characterized by ataxia, ophthalmoplegia, and areflexia. Miller Fisher syndrome can present with uncommon symp...

    Authors: Karan N. Ramakrishna, Vikrant Tambe, Adithya Kattamanchi and Amit S. Dhamoon

    Citation: Journal of Medical Case Reports 2020 14:31

    Content type: Case report

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  36. Squamous cell carcinomas of the rectum are extremely rare and their pathogenesis is still under debate. Their proper diagnosis and treatment may thus be challenging.

    Authors: P. Tschann, D. Lechner, B. Feurstein, B. Abendstein, S. Dertinger, A. Bösl, N. Vitlarov, F. Offner and I. Königsrainer

    Citation: Journal of Medical Case Reports 2020 14:30

    Content type: Case report

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  37. Atrial myxoma remains a rare clinical entity with an incidence of surgically resected cases of 0.5–0.7 per million population and prevalence of < 5 per 10,000. It typically manifests in woman after third decad...

    Authors: Suraj Shrestha, Akash Raut, Amar Jayswal, Randhir Sagar Yadav and Chandra Mani Poudel

    Citation: Journal of Medical Case Reports 2020 14:29

    Content type: Case report

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    The Correction to this article has been published in Journal of Medical Case Reports 2020 14:42

  38. Agenesis of the corpus callosum can occur isolated or as part of a complex congenital syndrome. Patients with isolated agenesis of the corpus callosum may present with severe intellectual disability, although ...

    Authors: Parménides Guadarrama-Ortiz, José Alberto Choreño-Parra and Tania de la Rosa-Arredondo

    Citation: Journal of Medical Case Reports 2020 14:28

    Content type: Case report

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  39. Proximal femoral focal deficiency is an extremely rare congenital anomaly with an incidence of 1.1–2.0 in 100,000 live births. It is a dysplastic phenomenon with predilections for the proximal two-thirds of th...

    Authors: Felix U. Uduma, Edwin M. Dim and Ngozi R. Njeze

    Citation: Journal of Medical Case Reports 2020 14:27

    Content type: Case report

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  40. Treatment of active rheumatoid arthritis may necessitate a methotrexate mono- or combination therapy. As in the present case, novel side effects may occur, when escalating therapy.

    Authors: Rainer Ullrich Pliquett, Christoph Lübbert, Christoph Schäfer and Matthias Girndt

    Citation: Journal of Medical Case Reports 2020 14:26

    Content type: Case report

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  41. The treatment for sliding esophageal hernia with mild gastroesophageal reflux is usually conservative, but surgical treatment is recommended for refractory sliding esophageal hernia, paraesophageal hernia liab...

    Authors: Nicola Tartaglia, Giovanna Pavone, Alessandra Di Lascia, Fernanda Vovola, Francesca Maddalena, Alberto Fersini, Mario Pacilli and Antonio Ambrosi

    Citation: Journal of Medical Case Reports 2020 14:25

    Content type: Case report

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  42. Bradycardia and syncope are known sequelae of brain lesions. However, in the absence of neurological signs and symptoms, bradycardia and syncope are often investigated purely from the cardiovascular perspectiv...

    Authors: Dmitri Pchejetski, Mojiba Kenbaz, Heba Alshaker and Kiruparajan Jesudason

    Citation: Journal of Medical Case Reports 2020 14:24

    Content type: Case report

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