Articles

Subcapsular hepatic hematoma as a complication of severe preeclampsia: a case report

Subcapsular hepatic hematoma is a rare and life-threatening complication of pregnancy. It is most commonly associated with severe preeclampsia and hemolytic anemia, elevated liver enzymes, and low platelets sy...

Authors: Kiel Luhning, Hilary MacCormick, Bruce Macaulay, Marianna Saunders and Catherine Craig

Pythium insidiosum keratitis reported in China, raising the alertness to this fungus-like infection: a case series

The objective of this study is to report typical clinical and laboratory characteristics of three cases of keratitis caused by Pythium insidiosum in China.

Authors: Hongyan Hou, Yue Wang, Lei Tian, Feng Wang, Ziyong Sun and Zhongju Chen

COVID-19 and chronic diabetes: the perfect storm for reactivation tuberculosis?: a case series

The coronavirus disease 2019 pandemic is predicted to have a net negative effect on tuberculosis control, with an estimated excess of 6.3 million tuberculosis cases and 1.4 million deaths by 2025. Programmatic...

Authors: Genesis P. Aguillón-Durán, Ericka Prieto-Martínez, Doris Ayala, Juan García Jr., John M. Thomas III, Juan Ignacio García, Brandon Michael Henry, Jordi B. Torrelles, Joanne Turner, Eder Ledezma-Campos and Blanca I. Restrepo

Thymoma may explain the confusion: a case report

The association of inflammatory myopathy and myasthenia gravis is a rarely described entity whose clinical presentation has always been intriguing because of the great clinical similarity between these two pat...

Authors: Abdelkhaleq Maaroufi, Naoufal Assoufi, Mohamed Amine Essaoudi and Jamal Fatihi

Gamma-hydroxybutyric acid-induced organic delirium complicated by polydrug use successfully treated with electroconvulsive therapy: a case report

Patients with gamma-hydroxybutyric acid withdrawal symptoms are at high risk of developing organic delirium, which can be fatal. The recommended first-line treatment is benzodiazepines, but treatment-resistant...

Authors: Mads F. Kjærgaard, Poul Videbech, Jens J. Nørbæk and Bjørn H. Ebdrup

Congenital ureterovaginal fistula: a rare case of single-system ectopic ureter with ipsilateral ectopic kidney managed by vaginal approach: a case report

Diagnosing urinary incontinence from organic causes such as ectopic ureter is particularly important because of the potential for cure by surgical correction. The prevalence of ectopic ureter is uncertain beca...

Authors: Demisew Amenu, Andebet Asmare and Ahmed Siraj

Idiopathic pulmonary fibrosis diagnosed concomitantly with diffuse squamous cell lung cancer on surgical lung biopsy: a case report

Idiopathic pulmonary fibrosis is a disease with a poor prognosis and has been associated with increased lung cancer incidence.

Authors: C. Niel, C. Ricordel, T. Guy, M. Kerjouan, B. De Latour, D. Chiforeanu, M. Lederlin and S. Jouneau

Efficacy of denosumab therapy for a 12-year-old female patient with Williams syndrome with osteoporosis and history of fractures: a case report

A decrease in bone mineral density is common in patients with Williams syndrome. However, appropriate management for osteoporosis in Williams syndrome patients has not been established. We report the case of a...

Authors: Masashi Uehara, Yukio Nakamura, Takako Suzuki, Noriko Sakai and Jun Takahashi

Rapid progression of chorioretinal atrophy in punctate inner choroiditis: a case report

The chorioretinal inflammatory lesions occurring in punctate inner choroiditis evolve into punched-out atrophic scars. Typically, the progression is gradual. We report a case of highly myopic punctate inner ch...

Authors: Yuka Kasuya, Yuji Inoue, Satoru Inoda, Yusuke Arai, Hidenori Takahashi, Hidetoshi Kawashima and Yasuo Yanagi

Recurrent autoimmune hypophysitis treated with rituximab: a case report

Autoimmune hypophysitis is a rare condition that often results in enlargement of the pituitary gland and hypopituitarism due to inflammatory infiltration. Management of autoimmune hypophysitis can include long...

Authors: Maria Kruse, Thomas Bastholm Olesen, Ljubo Markovic, Dorte Glintborg and Marianne Skovsager Andersen

Evidence of an active Cushing reflex in a preterm neonate with hyaline membrane disease: a case report

The Cushing reflex does not appear to have been described in preterm neonates. This case report shows the presence of an active Cushing reflex in a 32-week preterm neonate with hyaline membrane disease.

Authors: Alan D. Rothberg, Johan Smith and Welma Lubbe

Atypical drainage of a persistent left vena cava superior into the left atrial appendage detected by multidimensional imaging: a case report and review of the literature

While it is the most common thoracic venous anomaly, a persistent left vena cava superior may present in atypical variations, which are important to consider during clinical management.

Authors: Sophie Lengning, René Aschenbach, P. Christian Schulze and Marcus Franz

A full-term pregnant woman with secondary Evans syndrome caused by severe coronavirus disease 2019: a case report

In this report, we describe a very challenging case of a patient with secondary Evans syndrome caused by severe coronavirus disease 2019 infection in a pregnant full-term woman.

Authors: Damai Santosa, Muchlis A. U. Sofro, Farida, Nurvita Nindita, Eko A. Pangarsa, Budi Setiawan, Daniel Rizky and Catharina Suharti

Free gracilis end-to-side microanastomosis to a peronea arteria magna: a case report

Complex orthoplastic lower limb trauma in individuals with multiple injuries requires considerable resources and interdisciplinary collaboration for good outcomes. We present the first reported end-to-side fre...

Authors: Dallan Dargan, Raghuram Lakshminarayan and Cher Bing Chuo

Prominent rash and multisystem inflammatory syndrome in a 29-year-old patient with COVID-19: a case report

Adult patients with coronavirus disease present primarily with respiratory symptoms, but children and some adults may display a more systemic inflammatory syndrome with rash, fever, mucosal changes, and elevat...

Authors: Catherine A. Gao, James M. Walter and Jane E. Dematte D’Amico

Parsonage–Turner syndrome following coronavirus disease 2019 immunization with ChAdOx1-S vaccine: a case report and review of the literature

Parsonage–Turner syndrome is an acute peripheral neuropathy that affects the upper brachial plexus region. Previously published reports demonstrate that the condition can be triggered by surgery, infection, au...

Authors: Bruno Kusznir Vitturi, Marina Grandis, Sabrina Beltramini, Andrea Orsi, Angelo Schenone, Giancarlo Icardi and Paolo Durando

Extensive bilateral diffuse infiltrates and deterioration of lung following infection with severe acute respiratory syndrome coronavirus 2 in a pregnant woman: a case report

Severe acute respiratory syndrome coronavirus 2 is the third member of the coronavirus family to cause global concern in the twenty-first century. Pregnant women are particularly at higher risk of developing s...

Authors: Somayeh Moeindarbary, Salmeh Dadgar, Parvaneh Layegh, Zahra Shahriari, Faezeh Fayyaz, Sina Danesteh, Mahdi Rafiee and Milad Bahrami

Case series: coronavirus disease 2019 infection as a precipitant of atypical hemolytic uremic syndrome: two case reports

Atypical hemolytic uremic syndrome is an exceedingly rare thrombotic microangiopathy caused by accelerated activation of the alternative complement pathway.

Authors: Christine J. Kurian, Zachary French, Patrick Kukulich, Matthew Lankiewicz, Sushil Ghimire, Omar H. Maarouf, Sanaa Rizk and Ruben Rhoades

Delirium and other neuropsychiatric manifestations of COVID-19 infection in people with preexisting psychiatric disorders: a systematic review

Psychiatric disorders increase risk of neuropsychiatric disease and poor outcomes, yet little is known about the neuropsychiatric manifestations of COVID-19 in the psychiatric population. The primary objective...

Authors: Emma A. van Reekum, Tea Rosic, Anjali Sergeant, Nitika Sanger, Myanca Rodrigues, Reid Rebinsky, Balpreet Panesar, Eve Deck, Nayeon Kim, Julia Woo, Alessia D’Elia, Alannah Hillmer, Alexander Dufort, Stephanie Sanger, Lehana Thabane, Lawrence Mbuagbaw…

Simultaneous traumatic dislocation of the posterior tibial tendon and long peroneal tendon: a case report

Viewing the existing literature, one can find several documents about dislocation of the peroneal tendons. Clinical findings, diagnostics, and therapy are well described. Instead, the list of documents describ...

Authors: Johannes Riecke, Max Müller, Andreas Bölderl and Konstantin Genelin

Severe leptospirosis complicated with multiorgan dysfunction successfully managed with plasma exchange: a case report

Leptospirosis is a common zoonotic infection caused by the spirochete Leptospira. The disease is more prevalent in the tropics, causing subclinical to severe illness leading to high morbidity and mortality.

Authors: Manana Dewage Sankani Vishvara Kularathna, Senanayake Abeysinghe Mudiyanselage Kularatne, Manoji Pathirage and Pala Thanthirige Madhushi Anuradha Nanayakkara

Transcranial direct electrical stimulation for hand function in a stroke patient with severe upper limb paralysis due to lenticulostriate artery occlusion: a case report

Transcranial direct current stimulation, a therapeutic modality to modulate the excitability of injured and uninjured brain hemispheres in stroke patients, is expected to be effective in treating upper limb pa...

Authors: Koichiro Hirayama, Takeshi Fuchigami and Shu Morioka

Proposed protocol for treatment of severe periodontitis without platelet transfusion in patients with aplastic anemia: a case report

Aplastic anemia is an intractable disease characterized by pancytopenia, susceptibility to infection, and difficulty in achieving hemostasis. In patients with severe periodontal disease and aplastic anemia, sp...

Authors: Satoru Morikawa, Kazuya Watanabe, Satoshi Usuda, Yoko Miyashita and Taneaki Nakagawa

Methotrexate-induced toxidermia and pancytopenia in a patient with ectopic pregnancy: a case report

Methotrexate is an anticancer drug from the antimetabolite class. It is also used in gynecology and obstetrics and is the molecule of choice for the medical treatment of ectopic pregnancies. We report a case o...

Authors: Valéry Refeno, Naharisoa Giannie Rasamimanana, Baco Abdallah Abasse, Malalafinaritra Patrick Marco Ramarokoto, Mahefaniaina Jean Eustache Fanomezantsoa and Pierana Gabriel Randaoharison

Sternal swelling presenting as tuberculosis: a case report

Tuberculosis continues to be a worldwide public health problem. Despite the noted gradual decline in tuberculosis case rates in the UK, clinicians should still be aware of these unusual presentations. Sternal ...

Authors: John Rajan and Khaled Bizanti

Pure red cell aplasia secondary to rheumatoid arthritis: a case report

Rheumatoid arthritis is a common autoimmune disease with many extra-articular manifestations. Pure red cell aplasia is a rare manifestation of rheumatoid arthritis and is sparsely documented in the literature,...

Authors: Suneth Weerasinghe, Parackrama Karunathilake, Udaya Ralapanawa, Thilak Jayalath, Shamali Abeygunawardena and Manel Rathnayaka

Managing solar retinopathy with suprachoroidal triamcinolone acetonide injection in a young girl: a case report

Solar retinopathy is a disease that causes photochemical toxicity in the retinal fovea tissues, leading to an acute decrease of vision.

Authors: Ameen Marashi, Marwa Baba and Aya Zazo

Dark urine as the initial manifestation of COVID-19: a case report

Rhabdomyolysis is defined as a syndrome consisting of muscle necrosis and the release of intracellular muscle components into the bloodstream. Although rhabdomyolysis has been previously reported as an initial...

Authors: Goar Egoryan, Sana Chaudry, Kritika Yadav, Tianyu Dong, Emre Ozcekirdek, Ece Ozen and Guillermo Rodriguez-Nava

Rabies is still a fatal but neglected disease: a case report

Rabies, caused by a lyssavirus, is a viral zoonosis that affects people in many parts of the world, especially those in low income countries. Contact with domestic animals, especially dogs, is the main source ...

Authors: Y. A. Amoako, P. El-Duah, A. A. Sylverken, M. Owusu, R. Yeboah, R. Gorman, T. Adade, J. Bonney, W. Tasiame, K. Nyarko-Jectey, T. Binger, V. M. Corman, C. Drosten and R. O. Phillips

Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report

Progressive supranuclear palsy is a neurodegenerative condition that worsens over time. Given the lack of targeted treatments, patients with severe progressive supranuclear palsy have very low life expectancy.

Authors: Huiping Li, Fang Yuan, Yaming Du, Tao Pan, Wanxin Wen, Shaoxue Li, Lixin Wang and Aili Lu

Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report

Uterine sarcoma accounts for 3–7% of uterine malignant neoplasms. It is more aggressive than epithelial neoplasms, and patients have a poor prognosis. Rhabdomyosarcoma is classified as a heterologous uterine s...

Authors: Soheila Aminimoghaddam, Ali Rahbari and Roghayeh Pourali

Interferon-induced sarcoidosis with uveitis as the initial symptom: a case report and review of the literature

In recent years, numerous studies have reported the development or exacerbation of sarcoidosis due to interferon therapy. However, ocular lesions rarely present as initial symptoms. Herein, we describe a rare ...

Authors: Ai Kato, Mami Ishihara and Nobuhisa Mizuki

Transient congenital hyperinsulinism and hemolytic disease of a newborn despite rhesus D prophylaxis: a case report

In neonates, rhesus D alloimmunization despite anti-D immunoglobulin prophylaxis is rare and often unexplained. Rhesus D alloimmunization can lead to hemolytic disease of the newborn with anemia and unconjugat...

Authors: Sandra Simony Tornoe Riis, Marianne Hoerby Joergensen, Kristina Fruerlund Rasmussen, Steffen Husby, Jane Preuss Hasselby, Lise Borgwardt, Klaus Brusgaard, Christina Ringmann Fagerberg and Henrik Thybo Christesen

Symptomatic severe acute respiratory syndrome coronavirus 2 reinfection in a lupus patient treated with hydroxychloroquine: a case report

Hydroxychloroquine and chloroquine have been used for hospitalized coronavirus disease 2019 patients because of their antiviral and anti-inflammatory function. However, little research has been published on th...

Authors: Astrid Muyldermans, Piet Maes, Tony Wawina-Bokalanga, Tine Anthierens, Olivier Goldberg, Magali Bartiaux, Oriane Soetens, Ingrid Wybo, Sigi Van den Wijngaert and Denis Piérard

Correction to: May–Thurner syndrome, a diagnosis to consider in young males with no risk factors: a case report and review of the literature

Authors: Joel Hng, Shu Su and Noel Atkinson

Inferior vena cava thrombosis as a possible cause of nephrotic-range proteinuria: two case reports

Nephrotic-range proteinuria is a common reason for nephrological consultation in clinical practice. The differential diagnosis is wide, and generally focuses on different forms of glomerulonephritis, but other...

Authors: Yana Apostolova, Patricia Mehier, Salah D. Qanadli and Menno Pruijm

New Delhi metallo-β-lactamase-1 among Escherichia coli strains isolated from leukemia patients in Iran: two case reports

Escherichia coli has appeared as an important opportunistic pathogen responsible for nosocomial infections in patients with immunodeficiency, particularly in leukemia patients. New Delhi metallo-beta-lactamase is...

Authors: Mahdane Roshani, Alireza Goodarzi, Sanaz Dehbashi, Farhad Afrasiabi, Hossein Goudarzi, Ali Hashemi and Mohammad Reza Arabestani

Irreversible electroporation for pancreatic cancer using intraprocedural cone-beam computed tomography fusion navigation: a case report

Patients diagnosed with locally advanced pancreatic cancer are usually not eligible for surgical resection because of significant vascular involvement. Stereotactic body radiation therapy and chemotherapy are ...

Authors: Sriram Rao, Thanh-Lan Bui, Ali Sasani, Ben Sadeghi, Anvesh Macherla, Roozbeh Houshyar and Nadine Abi-Jaoudeh

Carboxymethylcellulose excipient allergy: a case report

Excipients are widely used in pharmaceuticals, detergents, food, and drink because of their properties of low toxicity and hypoallergenicity. The excipient carboxymethylcellulose is used extensively as a thick...

Authors: Katherine Townsend, James Laffan and Grant Hayman

Effectiveness of convalescent plasma therapy in eight non-intubated coronavirus disease 2019 patients in Indonesia: a case series

Severe acute respiratory syndrome coronavirus 2, the cause of coronavirus disease 2019, has become a global pandemic. Currently, there is no definitive treatment for coronavirus disease 2019. Convalescent plas...

Authors: Theresia Monica Rahardjo, Elizabeth Yogipranata, Ardian Hediyanto Naswan, Fitri Rahayu Sari, Fajar Budiono, Hernawati Permatasari and C. H. R. Driantik Chuntari

Bilateral basal ganglia ischemia associated with COVID-19: a case report and review of the literature

Coronavirus disease 2019, caused by the severe acute respiratory syndrome coronavirus 2, has a broad clinical spectrum, from asymptomatic to multi-organ dysfunction. Acute cerebrovascular events associated wit...

Authors: Khurram Khaliq Bhinder, Ahsun Rizwan Siddiqi, Muhammad Junaid Tahir, Hamza Maqsood, Irfan Ullah and Zohaib Yousaf

Afatinib for the treatment of advanced non-small-cell lung cancer harboring an epidermal growth factor receptor exon 18 E709_T710delinsD mutation: a case report

The discovery of epidermal growth factor receptor oncogenic driver mutations has changed the therapeutic landscape of advanced non-small cell lung cancer in the past decade. Since the introduction of next-gene...

Authors: Lander Van Acker, Dieter Stevens, Karim Vermaelen and Veerle Surmont

Augmentation mammaplasty by superolateral thoracic flap: a case report

The lateral chest wall is intimately associated with the esthetics of the breast. Patients with massive weight loss often have excess skin and fat in the lateral thoracic region causing functional, esthetic, a...

Authors: Elise Lupon, Benoit Chaput and Thomas Meresse

Uncertainty of leukoencephalopathies: a case report

Adult-onset leukoencephalopathies are a group of heterogeneous disorders characterized by white matter abnormalities. Leukoencephalopathy is usually encountered in children, but here we report a case with adul...

Authors: Mohamed A. Taha and T. Scott Diesing

Carney’s triad in an adult male from a tertiary care center in India: a case report

Carney’s triad is a rare syndrome comprising gastrointestinal stromal tumor, extra-adrenal paraganglioma, and pulmonary chondroma along with newer additions of adrenal adenoma and esophageal leiomyoma. The tri...

Authors: Ghazal Tansir, Nihar Ranjan Dash, Saurabh Galodha, Prasenjit Das, Shamim Ahmed Shamim and Sameer Rastogi

Guillain–Barré syndrome with bilateral facial diplegia secondary to severe acute respiratory syndrome coronavirus-2 infection: a case report

The new coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) owing to its similarity to the previous severe acute respiratory syndrome (SARS), is characterized by causing, in most...

Authors: Natalia Ramirez, David Ujueta, Luis Felipe Diaz, Lucila Emilse Folleco, Andrea Rodríguez, Ivan Gaona and Mauricio O. Nava-Mesa

Pneumatosis intestinalis associated with lenvatinib during thyroid cancer treatment: a case report

Pneumatosis intestinalis is a rare disease characterized by gas-filled cysts within the submucosa or serosa of the intestinal tract. In recent years, pneumatosis intestinalis was reported in patients undergoin...

Authors: Soji Toda, Hiroyuki Iwasaki, Daisuke Murayama, Maya Isoda, Hirotaka Nakayama, Nobuyasu Suganuma and Katsuhiko Masudo

“I took it off most of the time 'cause I felt comfortable”: unmasking, trusted others, and lessons learned from a coronavirus disease 2019 reinfection: a case report

Severe acute respiratory syndrome coronavirus 2 reinfection prevalence is unknown. It is essential to understand reinfection symptoms and, importantly, the lived experience.

Authors: Jacinda K. Dariotis, Stephanie M. Sloane and Rebecca Lee Smith

Shrinkage of a pituitary metastasis of melanoma induced by pembrolizumab: a case report

Pituitary metastases are rare, often deriving from lung or breast cancer owing to the upper vena cava proximity. Pituitary metastases can manifest with signs and symptoms of pituitary tumors, consequent to mas...

Authors: Giuseppe Giuffrida, Francesco Ferraù, Ylenia Alessi and Salvatore Cannavò

Sigmoid volvulus in pregnancy: a case report

Sigmoid volvulus in pregnancy is a rare cause of intestinal obstruction with high maternal and fetal morbidity and mortality if not diagnosed and managed early.

Authors: Jay Lodhia, Joachim Magoma, Joylene Tendai, David Msuya, Jamil Suleiman and Kondo Chilonga