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  1. Immune checkpoint inhibitor therapy has changed the standard drug therapy for relapsed or advanced non-small cell lung cancer; its efficacy is well-recognized by pulmonary physicians, oncologists, and thoracic...

    Authors: Takeo Hasegawa, Yuki Ozaki, Takuya Inoue, Yuzuru Watanabe, Mitsuro Fukuhara, Takumi Yamaura, Satoshi Muto, Naoyuki Okabe, Mitsunori Higuchi, Yutaka Shio and Hiroyuki Suzuki

    Citation: Journal of Medical Case Reports 2019 13:316

    Content type: Case report

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  2. Chronic total occlusion revascularization remains a challenging problem because of its complexity. We present a case of a patient with chronic total occlusion who was successfully revascularized with the use o...

    Authors: Yanzhuo Ma, Yuhong Peng, Gang Wang and Leisheng Ru

    Citation: Journal of Medical Case Reports 2019 13:315

    Content type: Case report

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  3. To determine the prevalence of and risk factors for malignant transformation of ovarian endometrioma during dienogest therapy, which is very rare, we examined multiple cases of malignant transformation of ovar...

    Authors: Michiko Honda, Wataru Isono, Akira Tsuchiya, Ako Saito, Hiroko Tsuchiya, Reiko Matsuyama, Akihisa Fujimoto and Osamu Nishii

    Citation: Journal of Medical Case Reports 2019 13:314

    Content type: Research article

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  4. Maternally inherited diabetes and deafness, and mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes are examples of mitochondrial diseases that are relatively common in the adult ...

    Authors: Mai Fukuda and Yoshiro Nagao

    Citation: Journal of Medical Case Reports 2019 13:313

    Content type: Case report

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  5. Thrombosis of the superior vena cava with propagation to the right heart chambers can be seen in the presence of chronic indwelling catheters. Moreover, the idiopathic right atrial thrombi may become entrapped...

    Authors: Elnaz Javanshir, Seyyed-Reza Sadat-Ebrahimi, Rezayat Parvizi, Mehrnoosh Toufan and Hosein Sate

    Citation: Journal of Medical Case Reports 2019 13:312

    Content type: Case report

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  6. Levothyroxine is a synthetic thyroxine and is the treatment of choice for hypothyroidism. It is a prohormone with minimal intrinsic activity. The drug is de-iodinated in peripheral tissue to form triiodothyron...

    Authors: Abbas F. Hlaihel and Mudher Z. H. Al-Khairalla

    Citation: Journal of Medical Case Reports 2019 13:311

    Content type: Case report

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  7. The association of macrophage activation syndrome and primary Sjögren’s syndrome has been rarely reported in the literature. We report the first observation of this association in Africa, south of the Sahara, ...

    Authors: B. S. Kane, M. Niasse, A. Faye, N. D. Diack, B. Djiba, M. Dieng, M. Sow, A. C. Ndao, N. Diagne, S. Ndongo and A. Pouye

    Citation: Journal of Medical Case Reports 2019 13:309

    Content type: Case report

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  8. Although epithelioid hemangiomas involving bone have been described in previous case reports and case series, the effects of radiation therapy on vertebral epithelioid hemangioma has not been fully reported. H...

    Authors: Aldis P. Siltumens, Na L. Smith, Rosalind F. Sharain, Michael G. Haddock and W. Michael Hooten

    Citation: Journal of Medical Case Reports 2019 13:308

    Content type: Case report

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  9. A coronary cameral fistula is a rare connection between a coronary artery and a cardiac chamber or vein bypassing the cardiac capillary bed system. Most of these fistulae are congenital and solitary, although ...

    Authors: Deogratias A. Nkya, Greenwood Sinyangwe and Farirai Fani Takawira

    Citation: Journal of Medical Case Reports 2019 13:307

    Content type: Case report

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  10. Hypercalcemia and aplastic anemia are two uncommon presentations of non-Hodgkin lymphoma that potentially worsen the disease prognosis. Although hypercalcemia has been reported in the B-cell subtypes and some ...

    Authors: Mickael Essouma, Dorothée M. Soh, Mazou N. Temgoua, Ronald M. Gobina, Aristide T. Nono, Etienne Olivier Atenguena, Mahamat Maimouna and Gloria E. Ashuntantang

    Citation: Journal of Medical Case Reports 2019 13:305

    Content type: Case report

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  11. Increased smartphone use among minors makes our population more prone to electrical injury. Despite regulations on electrical home safety standards, smartphones and chargers still pose a risk for severe injury...

    Authors: Sem F. Hardon, Pieter J. Haasnoot and Annebeth Meij- de Vries

    Citation: Journal of Medical Case Reports 2019 13:304

    Content type: Case report

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  12. Typhoid fever is a human-specific disease caused by a bacterium, Salmonella enterica subspecies enterica serovar Typhi. It is transmitted through ingestion of contaminated food or water. It is mostly diagnosed by...

    Authors: Aneley Getahun S., Josese Limaono, Raween Ligaitukana, Orisi Cabenatabua, Vika Soqo, Raape Diege and Mikaele Mua

    Citation: Journal of Medical Case Reports 2019 13:303

    Content type: Case report

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  13. Torque teno virus-induced aseptic meningitis has not been documented, although torque teno virus infections still remain under consideration for etiological agents. This study identified a torque teno virus se...

    Authors: Yoji Ikuta, Kunihiro Oba, Emina Nai, Tatsuo Katori, Masanori Hashino, Yuba Inamine, Satoko Matsunaga, Yutaro Yamaoka, Tsuyoshi Sekizuka, Akihide Ryo and Makoto Kuroda

    Citation: Journal of Medical Case Reports 2019 13:302

    Content type: Case report

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  14. Primary effusion lymphoma is a rare, high-grade non-Hodgkin’s lymphoma that usually occurs in immunosuppressed or human immunodeficiency virus-positive individuals in advanced stages of the disease. However, p...

    Authors: Liliana Fernández-Trujillo, John E. Bolaños, Mauricio Velásquez, Carlos García and Luz F. Sua

    Citation: Journal of Medical Case Reports 2019 13:301

    Content type: Case report

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  15. Although several cases of hepatitis B virus reactivation have been described in patients with a history of hepatitis B virus infection while undergoing treatment for hepatitis C virus infection with direct act...

    Authors: Luca Foroghi Biland, Ludovica Ferrari, Vincenzo Malagnino, Elisabetta Teti, Carlotta Cerva, Adele Gentile, Marianna Aragri, Romina Salpini, Valentina Svicher, Massimo Andreoni and Loredana Sarmati

    Citation: Journal of Medical Case Reports 2019 13:299

    Content type: Case report

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  16. Focal segmental glomerulosclerosis is characterized by partial (segmental) sclerotic lesions in some glomeruli (focal). Primary focal segmental glomerulosclerosis is generally considered resistant to steroid t...

    Authors: Arina Yamasaki, Daisuke Bito, Erina Eto, Keiichiro Matsumoto, Megumi Nakamura, Junji Miyazaki, Kenichi Matsumoto, Masanori Masuda, Daisuke Mori and Toru Yoshimura

    Citation: Journal of Medical Case Reports 2019 13:298

    Content type: Case report

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  17. A unicuspid aortic valve is a rare congenital cardiac abnormality. Despite its uncommon finding on an initial presentation, aortic insufficiency is accompanied with unicuspid aortic valve and this might reflec...

    Authors: Naoko Yuzawa-Tsukada, Toshikazu D. Tanaka, Satoshi Morimoto and Michihiro Yoshimura

    Citation: Journal of Medical Case Reports 2019 13:297

    Content type: Case report

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  18. According to experimental and clinical published studies, patients with keratoconus have a genetic predisposition to corneal ectasia; however, ectasia might not be activated or reactivated unless an additional...

    Authors: Georgios Labiris, Eirini-Kanella Panagiotopoulou, Panagiota Ntonti and Sergios Taliantzis

    Citation: Journal of Medical Case Reports 2019 13:296

    Content type: Case report

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  19. A traumatic bone cyst is an uncommon nonneoplastic lesion of the jaws that is considered as a “pseudocyst” because of the lack of an epithelial lining. This lesion is particularly asymptomatic and therefore is...

    Authors: Farnoosh Razmara, Zahra Ghoncheh and Ghazal Shabankare

    Citation: Journal of Medical Case Reports 2019 13:300

    Content type: Case report

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  20. Surgical reconstruction of large soft tissue defects of the upper back is challenging. Although the usefulness of free perforator flaps has been demonstrated, local options remain limited. The dorsal intercost...

    Authors: E. Lupon, A. G. Lellouch, F. Deilhes, B. Chaput and C. Berthier

    Citation: Journal of Medical Case Reports 2019 13:294

    Content type: Case report

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  21. Subpulmonic membrane as a cause of right ventricular outflow tract obstruction in patients with concordant ventriculoarterial connection and intact ventricular septum is considered to be rare. Association with...

    Authors: Meryem Haboub and Abdenasser Drighil

    Citation: Journal of Medical Case Reports 2019 13:291

    Content type: Case report

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  22. Human bocavirus 1 is a commonly detected human parvovirus. Many studies have shown human bocavirus 1 as a pathogen in association with acute respiratory tract infections in children. However, because human boc...

    Authors: Inga Ziemele, Man Xu, Anda Vilmane, Santa Rasa-Dzelzkaleja, Lea Hedman, Klaus Hedman, Maria Söderlund-Venermo, Zaiga Nora-Krukle, Modra Murovska and Dace Gardovska

    Citation: Journal of Medical Case Reports 2019 13:290

    Content type: Case report

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  23. Osteoporosis is a serious disease that causes bone fragility fractures and increases mortality. Bisphosphonates are the first-line drugs for osteoporosis. However, the gains in bone mineral density by use of b...

    Authors: Hidefumi Koiwai, Mikio Kamimura, Jun Takahashi, Yukio Nakamura and Hiroyuki Kato

    Citation: Journal of Medical Case Reports 2019 13:288

    Content type: Case report

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  24. Rapid diagnosis and appropriate treatment of Munchausen syndrome is important not only for the patient but also for health care workers because a delay in diagnosis can worsen patients’ clinical outcomes, and ...

    Authors: Naoki Iwanaga, Kazuko Yamamoto, Takahiro Takazono, Tomomi Saijo, Yoshifumi Imamura, Taiga Miyazaki, Koichi Izumikawa, Yoshihiro Yamamoto, Katsunori Yanagihara, Akira Yasuoka and Hiroshi Mukae

    Citation: Journal of Medical Case Reports 2019 13:287

    Content type: Case report

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  25. Generally, ovarian hyperstimulation syndrome develops after superovulation caused by ovulation-inducing drugs in infertile patients. However, ovarian hyperstimulation syndrome associated with natural pregnancy...

    Authors: Hiroaki Tsubokura, Yohei Ikoma, Takuya Yokoe, Tomoo Yoshimura and Katsuhiko Yasuda

    Citation: Journal of Medical Case Reports 2019 13:292

    Content type: Case report

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  26. Temporal artery biopsy is essential for the diagnosis of giant cell arteritis. It has been shown that 18F-fluorodeoxyglucose positron emission tomography-computed tomography, magnetic resonance angiography, and u...

    Authors: Toshio Kawamoto, Michihiro Ogasawara, Souichiro Nakano, Yuko Matsuki−Muramoto, Masakazu Matsushita, Kenjiro Yamanaka, Ken Yamaji and Naoto Tamura

    Citation: Journal of Medical Case Reports 2019 13:285

    Content type: Case report

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  27. Primary spontaneous pneumothorax is a common disorder occurring in young adults without underlying lung disease. Although tobacco smoking is a well-documented risk factor for spontaneous pneumothorax, an assoc...

    Authors: Alex Bonilla, Alexander J. Blair, Suliman M. Alamro, Rebecca A. Ward, Michael B. Feldman, Richard A. Dutko, Theodora K. Karagounis, Adam L. Johnson, Erik E. Folch and Jatin M. Vyas

    Citation: Journal of Medical Case Reports 2019 13:283

    Content type: Case report

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  28. A pseudoaneurysm is a rare but serious complication after transradial coronary catheterization. Although different treatment modalities have been proposed to treat post-catheterization pseudoaneurysm, only lim...

    Authors: Lingling Wu, Faris Haddadin, Joshua Berookhim, Justin Ratcliffe and Joseph Puma

    Citation: Journal of Medical Case Reports 2019 13:282

    Content type: Case report

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  29. NUT midline carcinoma is a rare and aggressive subset of squamous cell carcinoma, which is characterized by the translocation of nuclear protein in testis gene that is mostly fused with bromodomain and extrate...

    Authors: Leandro J. C. Oliveira, Aline B. L. Gongora, Marcela T. Latancia, Felipe G. Barbosa, João Vitor A. M. Gregorio, Leonardo A. Testagrossa, Mariane T. Amano and Olavo Feher

    Citation: Journal of Medical Case Reports 2019 13:279

    Content type: Case report

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  30. Primary sarcoma of the breast is rare. Surgery has been the only curative treatment available. Recently, neoadjuvant chemotherapy including anthracycline/ifosfamide has been reported effective for patients wit...

    Authors: Chieko Miyazaki, Mikio Shiozawa, Rintaro Koike, Kasumi Ogihara, Yumiko Sasaki, Satomi Shiba, Saki Nishida, Masako Sakuragi, Hirofumi Mizunuma, Takashi Fujita, Noriyoshi Fukushima, Alan K. Lefor, Joji Kitayama and Naohiro Sata

    Citation: Journal of Medical Case Reports 2019 13:289

    Content type: Case report

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  31. Dengue fever and dengue hemorrhagic fever incidence is increasing in Sri Lanka, especially among the young population. Uncommon presentations of this common illness make diagnostic dilemmas and can delay stand...

    Authors: W S Weerasinghe and Arjuna Medagama

    Citation: Journal of Medical Case Reports 2019 13:278

    Content type: Case report

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  32. Renal involvement in idiopathic hypereosinophilic syndrome is uncommon. The mechanism of kidney damage can be explained as occurring via two distinct pathways: (1) thromboembolic ischemic changes secondary to ...

    Authors: Diana Curras-Martin, Swapnil Patel, Huzaif Qaisar, Sushil K. Mehandru, Avais Masud, Mohammad A. Hossain, Gurpreet S. Lamba, Harry Dounis, Michael Levitt and Arif Asif

    Citation: Journal of Medical Case Reports 2019 13:281

    Content type: Case report

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  33. Familial glucocorticoid deficiency is a rare autosomal recessive disorder characterized by isolated glucocorticoid deficiency. Most patients are diagnosed following episodes of hypoglycemia or convulsion. We r...

    Authors: Kanchana Uyangoda, Phirarthana Kamalanathan and Sachith Mettananda

    Citation: Journal of Medical Case Reports 2019 13:280

    Content type: Case report

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  34. Eosinophilic esophagitis, once considered a rare disorder, has been increasingly recognized as a leading cause of dysphagia and food impaction in children and adults over the last few decades. It predominantly...

    Authors: Tanureet Kochar, Parminder Singh Dhingra, Muhammad Farhan Khaliq and Brittain Mcjunkin

    Citation: Journal of Medical Case Reports 2019 13:275

    Content type: Case report

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  35. Late cardiovascular disease-related adverse events are one of the most common causes of premature mortality among long-term survivors of childhood cancer. As it is difficult to reduce the heart dose with tradi...

    Authors: Gen Suzuki, Toshiyuki Ogata, Norihiro Aibe, Hideya Yamazaki, Shigeki Yagyu, Tomoko Iehara, Hajime Hosoi and Kei Yamada

    Citation: Journal of Medical Case Reports 2019 13:277

    Content type: Case report

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  36. Leprosy is a disease that was declared eliminated in 2010 from Nepal; however, new cases are diagnosed every year. The difficulty arises when the presentation of the patient is unusual.

    Authors: Shiva Raj K.C., Geetika K.C., Purnima Gyawali, Manisha Singh and Milesh Jung Sijapati

    Citation: Journal of Medical Case Reports 2019 13:276

    Content type: Case report

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  37. Berlin Heart EXCOR® pediatric ventricular assist device is a mechanical circulatory support device currently used in pediatric patients. Sotos syndrome is a well-described multiple anomaly syndrome characteriz...

    Authors: Rita Gravino, Giuseppe Limongelli, Andrea Petraio, Daniele Masarone, Maria Giovanna Russo, Ciro Maiello, Marina Verrengia, Danilo De Paulis and Giuseppe Pacileo

    Citation: Journal of Medical Case Reports 2019 13:286

    Content type: Case report

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  38. Multiple evanescent white dot syndrome most often resolves spontaneously without complications; however, choroidal neovascularization can sometimes occur.

    Authors: Maria Cristina Savastano, Marco Rispoli and Bruno Lumbroso

    Citation: Journal of Medical Case Reports 2019 13:274

    Content type: Case report

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  39. Dengue fever is a mosquito-borne illness prevalent mainly in the tropics. It is feared for causing the dengue hemorrhagic spectrum of the disease leading to significant morbidity and mortality. Its rarer manif...

    Authors: Jevon Yudhishdran, Isurujith Kongala Liyanage, Mitrakrishnan Rayno Navinan, Sandamalee Herath, Danushka Withanage, Sivakumar Jeyalakshmy and Aruna Kulatunga

    Citation: Journal of Medical Case Reports 2019 13:271

    Content type: Case report

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  40. The robot-assisted laparoscopic management of post-chemotherapy retroperitoneal metastasis and inferior vena cava tumor thrombus secondary to testicular cancer is a challenging task for urologists.

    Authors: Kai Zhang, Gang Zhu, Xingshuai Liu, Jiangke Tian, Yanfei Gu, Mengyao Zhai, Lu Yang, Wei Liu, Hongbo Li and Francisco J. Martinez Portillo

    Citation: Journal of Medical Case Reports 2019 13:272

    Content type: Case report

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  41. Musculoskeletal tuberculosis forms 10–25% of extrapulmonary tuberculosis which mainly involves the spine or weight-bearing joints. Tuberculous involvement of the sternum is a rare clinical entity even in count...

    Authors: Lovenish Bains, Pawan Lal, Tirlok Chand, Kamal Kishore Gautam, Mohd Yasir Beg and Pritesh Kumar

    Citation: Journal of Medical Case Reports 2019 13:267

    Content type: Case report

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