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  1. There are limited data on cardiovascular complications of coronavirus disease 2019 in pregnancy, and there are only a few case reports on coronavirus disease 2019 related cardiomyopathy in pregnancy. Different...

    Authors: Rahim Nejadrahim, Sara Khademolhosseini, Hadiseh Kavandi and Reza Hajizadeh

    Citation: Journal of Medical Case Reports 2021 15:143

    Content type: Case report

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  2. May–Thurner syndrome is an anatomical condition characterized by compression of the left common iliac vein by the right common iliac artery, causing venous outflow obstruction. It is an uncommon cause of deep ...

    Authors: Joel Zhen Khang Hng, Shu Su and Noel Atkinson

    Citation: Journal of Medical Case Reports 2021 15:141

    Content type: Case report

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  3. Increasingly widespread use of programmed cell death protein 1 (PD-1) immune checkpoint inhibitors (ICIs) for treatment of a variety of progressive malignancies continues to reveal a range of immune-related ad...

    Authors: Jacobi Hines, Ellen Daily, Anh Khoa Pham, Christopher R. Shea, Urooba Nadeem, Aliya N. Husain, Walter M. Stadler and Pankti Reid

    Citation: Journal of Medical Case Reports 2021 15:124

    Content type: Case report

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  4. Rectal signet ring cell carcinoma is a rare type of colorectal adenocarcinoma characterized by an aggressive biological behavior and poor prognosis. The co-occurrence of colorectal carcinoma and renal cell car...

    Authors: Blagica Krsteska, Rubens Jovanovic, Aleksandar Eftimov, Boro Ilievski, Dragan Hadzi-Mancev, Bujar Osmani and Slavica Kostadinova-Kunovska

    Citation: Journal of Medical Case Reports 2021 15:123

    Content type: Case report

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  5. Neurocysticercosis is the most common parasitic infection of the central nervous system, brain being the most frequent site. Intramedullary location of cysticercus is a rarely described entity in literature. W...

    Authors: Durjoy Lahiri, Abhishek Chowdhury, Souvik Dubey and Biman Kanti Ray

    Citation: Journal of Medical Case Reports 2021 15:139

    Content type: Case report

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  6. Gamma heavy chain disease (γ-HCD) is a monoclonal gammopathy defined by an abnormal clonal and isolated production of incomplete heavy chain gamma (γ), unable to bind with light chains kappa or lambda. This di...

    Authors: Gwenvaël Danic, Thomas Dejoie, Hélène Caillon, Aurélie Achille, Pierre Pottier and Christian Agard

    Citation: Journal of Medical Case Reports 2021 15:121

    Content type: Case report

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  7. Diffuse alveolar hemorrhage (DAH) is a rare, life-threatening condition that can present as a spectrum of nonspecific symptoms, ranging from cough, dyspnea, and hemoptysis to severe hypoxemic respiratory failu...

    Authors: Yumin Jo, Jagyung Hwang, Jieun Lee, Hansol Kang and Boohwi Hong

    Citation: Journal of Medical Case Reports 2021 15:137

    Content type: Case report

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  8. Corneal refractive surgeries cause epithelial damage and induce wound healing processes. To promote wound healing after photorefractive keratectomy, the effectiveness of an autologous platelet tissue graft was...

    Authors: Yoshinori Takayanagi, Shigeaki Kato and Masaru Okada

    Citation: Journal of Medical Case Reports 2021 15:122

    Content type: Case report

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  9. Shulman’s disease, or eosinophilic fasciitis (EF), is a rare autoimmune disease, characterized by sclerodermic skin lesions with progressive induration and thickening of the soft tissues. Chronic graft-versus-...

    Authors: Thomas Chalopin, Nicolas Vallet, Marion Morel, Raphael Maguet, Louis d’Alteroche, Gonzague de Pinieux, Olivier Hérault, Emmanuel Gyan, Laurent Sutton and Alban Villate

    Citation: Journal of Medical Case Reports 2021 15:135

    Content type: Case report

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  10. Darier–Ferrand dermatofibrosarcoma (DFS) is a rare malignant cutaneous neoplasm characterized by local aggressiveness, high risk of recurrence, and low metastatic potential.

    Authors: A. Triki, M. Aloui, M. Ghalleb, I. Jbir, Ben Naceur, J. Ben Hassouna, R. Chargui and K. Rahal

    Citation: Journal of Medical Case Reports 2021 15:120

    Content type: Case report

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  11. Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine tumor of the skin. It is associated with advanced age, ultraviolet (UV) radiation, and Merkel cell polyomavirus. It has a predilection for th...

    Authors: Alex F. Grubb and Elizabeth Hankollari

    Citation: Journal of Medical Case Reports 2021 15:118

    Content type: Case report

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  12. Locked twins is a rare and hazardous obstetric complication, which occurs in approximately 1:100 twin pregnancies. One of the known etiologic factors for locked twins is size of the twins. We report a case of ...

    Authors: Abraham Fessehaye, Ferid A. Abubeker and Mekdes Daba

    Citation: Journal of Medical Case Reports 2021 15:115

    Content type: Case report

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  13. Thyroid papillary carcinoma is one of the most common endocrine tumors, and it accounts for 85% of thyroid tumors. Adrenocorticotropic hormone (ACTH)-independent Cushing's syndrome is a rare disease. In this c...

    Authors: Mashallah Tabatabaizadeh, Sara Hasibi Taheri, Mohammad Eydi and Mohammad Shayestehpour

    Citation: Journal of Medical Case Reports 2021 15:113

    Content type: Case report

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  14. Hypermagnesemia can be a fatal condition and should be diagnosed early on. Most reports of hypermagnesemia have been of adults with impaired renal function. We describe the case of a pediatric patient without ...

    Authors: Kotaro Araki, Yuhei Kawashima, Miyuki Magota and Norio Shishida

    Citation: Journal of Medical Case Reports 2021 15:129

    Content type: Case report

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  15. Bilateral congenital diaphragmatic hernia (CDH) is very rare. A few studies have reported the pathogenic role of 5p in CDH.

    Authors: Noriyuki Nakamura, Takafumi Ushida, Yoshinori Moriyama, Kenji Imai, Tomoko Nakano-Kobayashi, Satoko Osuka, Maki Goto, Hiroaki Kajiyama, Hideyuki Asada, Masahiro Hayakawa and Tomomi Kotani

    Citation: Journal of Medical Case Reports 2021 15:114

    Content type: Case report

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  16. Isolated basilar artery dissection (IBAD) is a rare but important cause of ischemic stroke. Anti-thrombotic therapy is often used to treat IBAD-related ischemic stroke, but selected cases might need more aggre...

    Authors: Toshiaki Goda, Naoki Oyama, Takanori Iwamoto, Hiroki Takai, Shunji Matsubara, Masaaki Uno and Yoshiki Yagita

    Citation: Journal of Medical Case Reports 2021 15:119

    Content type: Case report

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  17. Oxalate nephropathy is a rare disorder that can result in acute kidney injury (AKI) and progresses to end-stage kidney disease (ESKD). The causes can be either primary or secondary. Primary hyperoxaluria inclu...

    Authors: Tala Mahmoud, Elias C. Ghandour and Bernard G. Jaar

    Citation: Journal of Medical Case Reports 2021 15:106

    Content type: Case report

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  18. T cell-mediated eosinophilia is associated with numerous conditions—including atopic dermatitis, food allergies, and asthma—collectively known as the “atopic march.” Benralizumab is a recombinant, humanized, a...

    Authors: David N. Pham

    Citation: Journal of Medical Case Reports 2021 15:103

    Content type: Case report

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  19. Extranodal NK/T cell lymphoma (ENKTL) is an aggressive form of Epstein-Barr virus (EBV)-associated non-Hodgkin’s lymphoma which historically has a poor prognosis. When relapse occurs, particularly in the cereb...

    Authors: Amanda E. Lipsitt, Jaclyn Y. Hung and Anne-Marie Langevin

    Citation: Journal of Medical Case Reports 2021 15:102

    Content type: Case report

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  20. Perforation of the cornea is a rare finding in patients with rheumatoid arthritis (RA). Addressing a perforated cornea associated with RA is challenging, since its pathogenesis is not fully elucidated. Topical...

    Authors: Simona Delia Nicoară and Ioana Damian

    Citation: Journal of Medical Case Reports 2021 15:116

    Content type: Case report

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  21. Aplasia cutis congenita is regarded as congenital focal absence of skin in the newborn, and occurrence of more than three similar skin defects is rare. The etiology is thought to be multifactorial, and precise...

    Authors: V. Thadchanamoorthy, Kavinda Dayasiri, M. Thirukumar, N. Thamilvannan and S. H. Chandraratne

    Citation: Journal of Medical Case Reports 2021 15:110

    Content type: Case report

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  22. Breast tuberculosis, also known as tuberculous mastitis, is an extremely rare form of tuberculosis. It accounts for <0.1% of all breast diseases and <2% of all cases of tuberculosis. It is often misdiagnosed a...

    Authors: Yuka Sagara, Shuji Hatakeyama, Ayako Kumabe, Masako Sakuragi and Masami Matsumura

    Citation: Journal of Medical Case Reports 2021 15:101

    Content type: Case report

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  23. Severe acute respiratory syndrome coronavirus 2 infection can lead to a constellation of viral and immune symptoms called coronavirus disease 2019. Emerging literature increasingly supports the premise that se...

    Authors: Artem Minalyan, Franklin L. Thelmo, Vincent Chan, Stephanie Tzarnas and Faizan Ahmed

    Citation: Journal of Medical Case Reports 2021 15:112

    Content type: Case report

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  24. Most sudden-onset hearing loss is due to otolaryngologic- and very rarely to cerebrovascular disease. We report a woman with sudden bilateral sensorineural hearing loss. This case suggests that even in the abs...

    Authors: Tomoya Kinouchi, Keisuke Ishitani, Shinichi Uyama, Tadashi Miyamoto, Naomi Fujimoto and Hiromi Ueta

    Citation: Journal of Medical Case Reports 2021 15:111

    Content type: Case report

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  25. Pneumatosis intestinalis (PI) is a rare entity which refers to the presence of gas within the wall of the small bowel or colon which is a radiographic sign. The etiology and clinical presentation are variable....

    Authors: M. C. Martín-Soberón, S. Ruiz, G. De Velasco, R. Yarza, A. Carretero, D. Castellano and J. M. Sepúlveda-Sánchez

    Citation: Journal of Medical Case Reports 2021 15:109

    Content type: Case report

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  26. Dermoid cysts are well-known lesions that manifest as subcutaneous tumors around the lateral sides of the eyebrows in young patients. Computed tomography or magnetic resonance imaging (MRI) is often performed ...

    Authors: Taro Mikami, Chie Maeda, Fumihiko Aoki, Toshinori Iwai, Yuichiro Yabuki, Tetsuhiko Okabe, Kenichi Ohashi and Jiro Maegawa

    Citation: Journal of Medical Case Reports 2021 15:99

    Content type: Case report

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  27. Pregnancy seems to increase the risk of thrombotic thrombocytopenic purpura (TTP) relapses and make the TTP more severe in any of the pregnancy trimesters, or even during the postpartum period.

    Authors: Soheila Aminimoghaddam, Narjes Afrooz, Setare Nasiri, Ozra Motaghi Nejad and Fatemeh Mahmoudzadeh

    Citation: Journal of Medical Case Reports 2021 15:104

    Content type: Case report

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  28. Hemophagocytic lymphohistiocytosis (HLH) is characterized by hyperinflammation and life-threatening cytopenias. Survival is poor, and management is pivotal on rapid identification of the disease. HLH is associ...

    Authors: Y. Sun, C. Blieden, B. Y. Merritt, R. Sosa and Gustavo Rivero

    Citation: Journal of Medical Case Reports 2021 15:98

    Content type: Case report

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  29. Lichen planus is a rare autoimmune disease primarily affecting the skin and mucous membranes of the oral mucosa, vulva, and vagina. Diagnosis is difficult and often delayed as the clinicians do not associate t...

    Authors: Lajya Devi Goyal, Priyanka Garg and Manmeet Kaur

    Citation: Journal of Medical Case Reports 2021 15:97

    Content type: Case report

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  30. We report a high-risk case of a coronavirus disease 19 (COVID-19)-positive patient with comorbidities including diabetes mellitus (DM), hypertension (HTN), hypothyroidism and chronic kidney disease (CKD), trea...

    Authors: Alka Mishra, Sumitra A. Bentur, Sonika Thakral, Rahul Garg and Bhanu Duggal

    Citation: Journal of Medical Case Reports 2021 15:95

    Content type: Case report

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  31. Arthritis is rarely reported as a paraneoplastic manifestation of occult malignancy. We report herein two cases of paraneoplastic arthritis due to occult malignancy.

    Authors: Benjamin Sachdev Manjit Singh, Sharifah Aishah Wan, Yaw Kiet Cheong, Seow Lin Chuah, Cheng Lay Teh and Ahmad Tirmizi Jobli

    Citation: Journal of Medical Case Reports 2021 15:94

    Content type: Case report

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  32. Current management of choledocholithiasis entails the use of endoscopic retrograde cholangiopancreatography (ERCP) and clearance of the common bile duct. A rare complication of this procedure is the impaction ...

    Authors: Ibrahim Abu Shakra, Maxim Bez, Amitai Bickel, Mahran Badran, Fahed Merei, Samer Ganam, Walid Kassis and Eli Kakiashvili

    Citation: Journal of Medical Case Reports 2021 15:93

    Content type: Case report

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  33. The risk of stroke after carotid sinus massage is greater if there is preexisting carotid stenosis or carotid plaques. We present the case of a patient with underlying 40% carotid stenosis, who developed a wat...

    Authors: Edgar R. Lopez-Navarro, Götz Greif, Carl-Albrecht Haensch, Adrian Ringelstein and Robert Larbig

    Citation: Journal of Medical Case Reports 2021 15:83

    Content type: Case report

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  34. The double-duct sign is defined as dilation of both the common bile duct and pancreatic duct, which usually indicates pancreatic malignancy. However, benign causes have also been reported to cause a double-duc...

    Authors: Naseem Al-Khoury, Okbah Mohamad, Abd Al-Jawad Mazloum and Maher Madi

    Citation: Journal of Medical Case Reports 2021 15:82

    Content type: Case report

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  35. An infected aortic aneurysm is a rare and life-threatening vascular condition with a high incidence of arterial rupture and recurrence even after treatment. One of the most common causes of an infected aortic ...

    Authors: Kiyoshi Takemoto, Michitaka Nakamura, Masaaki Sakuraya, Tomonori Yamamoto, Wataru Iwanaga, Kazuaki Atagi, Kazuo Yamanaka and Takeshi Matsuyama

    Citation: Journal of Medical Case Reports 2021 15:81

    Content type: Case report

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  36. Breast tuberculosis is a rare disease, even in endemic areas. The diagnosis can be challenging, as it can mimic breast cancer. We aim to report our experience and discuss diagnoses and management modalities.

    Authors: M. Ghalleb, S. Seghaier, O. Adouni, H. Bouaziz, A. Bouida, J. Ben Hassouna, R. Chargui and K. Rahal

    Citation: Journal of Medical Case Reports 2021 15:73

    Content type: Case report

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  37. Primary urethral carcinoma (PUC) is rare and accounts for < 1% of all genito-urinary cancers. There is a male predominance of 3:1 and a peak incidence in the 7th and 8th decades. The aetiology of this cancer i...

    Authors: Emily Walsh, Niall Kelly, Padraig Daly, Nigam Shah and Ivor Cullen

    Citation: Journal of Medical Case Reports 2021 15:91

    Content type: Case report

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  38. Very little is known about the risk that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral infection poses to cancer patients, many of whom are immune compromised causing them to be more susce...

    Authors: D. Madduri, S. Parekh, T. B. Campbell, F. Neumann, F. Petrocca and S. Jagannath

    Citation: Journal of Medical Case Reports 2021 15:90

    Content type: Case report

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  39. Tumor molecular screening allows categorization of molecular alterations to select the best therapeutic strategy. AT-rich interactive domain-containing 1A (ARID1A) gene mutations are present in gastric, endometri...

    Authors: Mercedes Durán, Iris Faull, Enrique Lastra, Jean-Francois Laes, Ana Belén Rodrigo and Ricardo Sánchez-Escribano

    Citation: Journal of Medical Case Reports 2021 15:89

    Content type: Case report

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  40. Mood and anxiety disorders are common in women of childbearing age, especially during the peripartum period. As more women seek medical management for these conditions, there is an increasing need for studies ...

    Authors: Greg J. Marchand, Katerina Meassick, Hannah Wolf, Sophia K. Hopewell, Katelyn Sainz, Sienna M. Anderson, Kelly Ware, Janelle Vallejo, Alexa King, Stacy Ruther, Giovanna Brazil, Kaitlynne Cieminski and Nicolas Calteux

    Citation: Journal of Medical Case Reports 2021 15:88

    Content type: Case report

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  41. Combination regimens that include immune checkpoint (ICI) and vascular endothelial growth factor (VEGF) inhibition have opened the door to new treatment opportunities for patients with metastatic renal cell ca...

    Authors: T. Anders Olsen, Dylan J. Martini, Sean T. Evans, Jamie M. Goldman and Mehmet Asim Bilen

    Citation: Journal of Medical Case Reports 2021 15:72

    Content type: Case report

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  42. Bronchial fistula is a severe complication of pneumonectomy with a high mortality rate. We previously reported a technique for bronchial closure to prevent bronchial fistula in a canine model. We described tha...

    Authors: Kimitaka Makidono, Yoshihiro Miyata, Takuhiro Ikeda, Yasuhiro Tsutani, Yuichiro Kai, Kei Kushitani, Yukio Takeshima and Morihito Okada

    Citation: Journal of Medical Case Reports 2021 15:71

    Content type: Case report

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