Articles

2-methylbutyryl-CoA dehydrogenase deficiency associated with autism and mental retardation: a case report

2-methylbutyryl-CoA dehydrogenase deficiency or short/branched chain acyl-CoA dehydrogenase deficiency (SBCADD) is caused by a defect in the degradation pathway of the amino acid L-isoleucine.

Authors: Oivind J. Kanavin, Berit Woldseth, Egil Jellum, Bjorn Tvedt, Brage S. Andresen and Petter Stromme

Successful outcome of a pregnancy in a woman with advanced cirrhosis due to hepatitis B surface antigenemia, delta super-infection and hepatitis C co-infection: a case report

Pregnancy in women with advanced liver disease is rare. In this paper we described the case of a successful pregnancy in a young woman with advanced cirrhosis due to hepatitis B surface antigenemia, hepatitis ...

Authors: Amna Subhan, Shahab Abid and Wasim Jafri

External beam irradiation of myocardial carcinoid metastases: a case report

The heart is an exceedingly rare site of metastatic involvement in carcinoid tumors. Only nineteen cases have been described in the literature over the past 30 years. We report here on a patient who presented ...

Authors: Jonathan Strosberg, Sarah Hoffe, Todd Hazelton and Larry Kvols

47,XXY/48,XXXY/49,XXXXY mosaic with hydrocephaly: a case report and review of the literature

Klinefelter's syndrome is a frequent genetic sexual alteration in males, associated with the 47,XXY aneuploidy. Several syndrome variants are caused by different X and Y polysomy and mosaicisms, including the ...

Authors: Jesús E. Dueñas-Arias, Maribel Aguilar-Medina, Eliakym Arámbula-Meraz, Juliana B. Valenzuela-Camacho, Angelina Vega-Solano, Julio Granados and Rosalío Ramos-Payán

Whole body bone scintigraphy in osseous hydatosis: a case report

Hydatid disease is common in many parts of the world, and causes considerable health and economic loss. This disease may develop in almost any part of the body.

Authors: Abdolali Ebrahimi, Majid Assadi, Mohsen Saghari, Mohammad Eftekhari, Amir Gholami, Reza Ghasemikhah and Sakineh Assadi

Left-sided appendicitis in a patient with congenital gastrointestinal malrotation: a case report

While appendicitis is the most common abdominal disease requiring surgical intervention seen in the emergency room setting, intestinal malrotation is relatively uncommon. When patients with asymptomatic undiag...

Authors: Frank J. Welte and Mario Grosso

An unusual exacerbation of chronic obstructive pulmonary disease (COPD) with herpes simplex tracheitis: case report

Chronic obstructive pulmonary disease (COPD) is a common cause of morbidity in the UK and is increasingly seen in elderly patients, often requiring multiple courses of steroids. We present a case of a 72 year ...

Authors: Alison C. Boland, Elizabeth H. Iveson and Mark W. Elliott

Congenital syphilis, still a reality in 21^st century: a case report

Congenital syphilis is a preventable disease and its presence reflects a failure of prenatal care delivery systems, as well as syphilis control programmes. The procedure to prevent congenital syphilis through ...

Authors: Monica Chaudhary, Bineeta Kashyap and Preena Bhalla

Spontaneous regression of metastatic renal cell carcinoma: case report

Spontaneous regression of metastatic renal cell carcinoma is rarely observed. A case of suspected spontaneous regression of pulmonary metastases following nephrectomy for histologically proven renal cell carci...

Authors: Katerina Lekanidi, Paraskevi A. Vlachou, Bruno Morgan and Subramaniam Vasanthan

A fatal case of bupropion (Zyban) hepatotoxicity with autoimmune features: Case report

Bupropion is approved for the treatment of mood disorders and as an adjuvant medication for smoking cessation. Bupropion is generally well tolerated and considered safe. Two randomized controlled trials of bup...

Authors: Fawwaz Humayun, Thomas M. Shehab, Joseph A. Tworek and Robert J. Fontana

Sublingual epidermoid cyst: a case report

Epidermoid and dermoid cysts represent less than 0.01% of all oral cavity cysts. The cysts can be defined as epidermoid when the lining presents only epithelium, dermoid cysts when skin adnexa are found, and t...

Authors: Tolga Kandogan, Murat Koç, Enver Vardar, Elif Selek and Özlem Sezgin

Extensive psoriasis induced by pegylated interferon: a case report

This paper describes the clinical course of a patient with chronic hepatitis C, genotype 2a/2c, previously treated with Interferon α2b and subsequently with Lymphoblastoid Interferon without any response, and ...

Authors: Vincenzo Citro, Raffaele Fristachi and Giovanni Tarantino

Occlusal management for a patient with aural symptoms of unknown etiology: a case report

Although the discrepancy between the habitual occlusal position (HOP) and the flat bite plate-induced occlusal position (BPOP) (regarded as the muscular physiological reference position) has been recently repo...

Authors: Kengo Torii and Ichiro Chiwata

An unusual presentation of multiple myeloma: a case report

Multiple myeloma can occasionally manifest with joint disease. We report the case of an individual with a progressive bilateral carpal syndrome and a symmetrical severe seronegative polyarthritis and joint swe...

Authors: Catherine B. Molloy, Rahul A. Peck, Stephen J. Bonny, Simon N. Jowitt, John Denton, Anthony J. Freemont and Abbas A. Ismail

Infiltrating ductal carcinoma breast with central necrosis closely mimicking ductal carcinoma in situ (comedo type): a case series

Here we present a series of infiltrative ductal carcinoma breast cases (infiltrative ductal carcinoma with central necrosis) so closely mimicking 'DCIS with central comedo necrosis' that on initial morphologic...

Authors: Shahid Pervez and Hassan Khan

Retroperitoneal haemorrhage in renal angiomyolipoma causing hepatic functional decompensation: a case report

Renal angiomyolipomata usually present as incidental findings on routine imaging, but rarely they may give rise to significant haemorrhage. If bleeding occurs, first-line treatment is currently angiography wit...

Authors: Julekha R Wajed, Simon D Taylor-Robinson, James E Jackson and Gordon WH Stamp

Bowel associated dermatosis – arthritis syndrome: a case report

We report a rare case of Bowel Associated Dermatosis – Arthritis Syndrome in a young patient with complex Crohn's disease who presented with fever, arthritis, rash and worsening of diarrhea with abdominal pain...

Authors: Dayavathi Ashok and Patrick Kiely

Spontaneous ventral urethral fistula in a young diabetic man: a case report

We present the first case reported in the medical literature of a patient with a spontaneous ventral urethral fistula accompanied by severe infection due to diabetes mellitus. A 34-year-old man with poor contr...

Authors: Stefan Denzinger, Wolf F Wieland, Maximilian Burger and Wolfgang Otto

Fatal miliary Coccidioidomycosis in a patient receiving infliximab therapy: a case report

A 78-year-old white male from Iowa in the United States of America receiving the anti- tumor necrois factor (TNF) agent infliximab therapy for rheumatoid arthritis developed a cheek ulcer which failed to respo...

Authors: Mark P Rogan and Karl Thomas

Multicentric Castleman's disease: a case report

Castleman's disease is a clinicopathological entity associated with lymphoproliferation. We report a case of a 71 year old gentleman who was initially clinically suspected to have lymphoma (owing to clinical f...

Authors: Brian F Menezes, Rosemary Morgan and Mohammed Azad

Dacryocystitis presenting as post-septal cellulitis: a case report

Dacryocystitis is relatively common, the majority of patients present with pre-septal cellulitis and not an orbital abscess due to anatomical barriers. The authors report a case of dacryocystitis presenting as...

Authors: Scott E Henney, Mike J Brookes, Kevin Clifford and Anirvan Banerjee

Life-saving automated external defibrillation in a teenager: a case report

Adolescent sudden death during sport participation is commonly due to cardiac causes. Survival is more likely when an automated external defibrillator (AED) is used soon after collapse.

Authors: Corsino Rey, Antonio Rodríguez-Nuñez, Alberto Medina and Juan Mayordomo

Anaphylactic reaction associated with Ranitidine in a patient with acute pancreatitis: a case report

Ranitidine is a widely used drug and is known to be well tolerated. This case report illustrates a severe anaphylactic reaction after a single intravenous dose of 50 mgs of ranitidine and highlights this unusu...

Authors: Ulfin Rethnam and Rajam Sheeja Yesupalan

Pituitary macroadenomas: are combination antiplatelet and anticoagulant therapy contraindicated? A case report

Pituitary apoplexy is a life-threatening endocrine emergency that is caused by haemorrhage or infarction of the pituitary gland, commonly within a pituitary adenoma. Patients classically present with headache,...

Authors: Tricia MM Tan, Carmela Caputo, Amrish Mehta, Emma CI Hatfield, Niamh M Martin and Karim Meeran

Bouveret's syndrome as an unusual cause of gastric outlet obstruction: a case report

An 83 year old caucasian gentleman presented with vomiting and left sided abdominal pain. A subsequent upper GI endoscopy demonstrated a large smooth mass impacted within the duodenum. A cholecysto-duodenal fi...

Authors: Deepak Joshi, Ali Vosough, Tom M Raymond, Chris Fox and Arun Dhiman

The "incidental" episode of ventricular fibrillation: a case report

Polymorphic ventricular tachycardia and ventricular fibrillation (VF) carry important prognostic implications, especially in the post myocardial infarction period. However, artifact on the electrocardiographic...

Authors: Fahim H Jafary

A patient with testicular pseudolymphoma – a rare condition mimicking malignancy: a case report

Three months following a right sided acute epididymitis a 62 year old patient presented with a painless right testicular swelling. Physical examination, scrotal ultrasound and operative exploration suggested m...

Authors: Roman Ganzer, Maximilian Burger, Matthias Woenckhaus, Wolf Ferdinand Wieland and Andreas Blana

A pulmonary artery false aneurysm after right middle lobectomy: a case report

Pulmonary artery false aneurysm is a rare condition, reported to complicate interventional procedures. We report a case of a false aneurysm of the interlobar pulmonary artery following a right middle lobectomy...

Authors: Hossam Shaaban, Hemant Sharma, Jagan Rao and Stephen Clark

Proton pump inhibitor-responsive chronic cough without acid reflux: a case report

Because 24-h esophageal pH monitoring is quite invasive, the diagnosis of gastroesophageal reflux disease (GERD)-associated cough has usually been made based merely on the clinical efficacy of treatment with p...

Authors: Kouichi Nobata and Hidetsugu Asanoi

Adult brain abscess associated with patent foramen ovale: a case report

Brain abscess results from local or metastatic septic spread to the brain. The primary infectious site is often undetected, more commonly so when it is distant. Unlike pediatric congenital heart disease, minor...

Authors: Georgios T Stathopoulos, Christina G Mandila, Georgios V Koukoulitsios, Nikodimos G Katsarelis, Michel Pedonomos and Andreas Karabinis

Vena cava inferior thrombosis detected by venous hum: a case report

We describe a patient in which a venous hum, heard during abdominal auscultation, lead to the diagnosis of a vena cava inferior thrombosis.

Authors: Robert Colebunders and Britt Colebunders

Hypernatremic dehydration, diabetes insipidus, and cerebral venous sinus thrombosis in a neonate: a case report

Authors: Laurene M Fleischer, Thomas A Wilson and Margaret M Parker

Ventricular tachycardia after administration of sildenafil citrate: a case report

It has not previously been reported that sildenafil citrate causes malignant arrhythmias in humans.

Authors: Jeppe G Rasmussen, Egon Toft and Ole Frøbert

Acute pancreatitis related to therapeutic dosing with colchicine: a case report

Colchicine is used in the treatment and prophylaxis of gout. It possesses a narrow therapeutic window, frequently resulting in dose-limiting gastrointestinal side-effects such as diarrhoea and emesis. As colch...

Authors: Joseph Yuk Sang Ting

Perigraft air is not always pathological: a case report

The presence of perigraft air is a common finding in the immediate post-operative phase following abdominal aortic aneurysm repair whilst the later appearance of air, in association with elevated inflammatory ...

Authors: Elizabeth Ball, Gareth Morris-Stiff, Mari Coxon and Michael H Lewis

Altered mental status, an unusual manifestation of early disseminated Lyme disease: A case report

Early disseminated Lyme disease can have a myriad of central nervous system manifestations. These run the gamut from meningitis to radiculopathy and cranial neuropathy. Here we present a case that manifested w...

Authors: Shiven B Chabria and Jock Lawrason

Laparoscopic resection of a primary hydatid cyst of the adrenal gland: a case report

Echinococcosis rates vary in different parts of the world. Italy is regarded as a middle to high risk country with over 1,000 cases requiring surgery each year. Liver (45–75%) and lung (10–50%) are the most fr...

Authors: Gianlorenzo Dionigi, Gianpaolo Carrafiello, Chiara Recaldini, Fausto Sessa, Luigi Boni, Francesca Rovera and Renzo Dionigi

Bilateral hilar lymphadenopathy in a young female: a case report

Hilar or mediastinal lymphadenopathy is not included in the wide spectrum of radiologic findings associated with bronchiolitis obliterans-organizing pneumonia (BOOP). We present a patient who presented with ex...

Authors: Seema Varma, Shilpi Gupta, Raymond ElSoueidi, Meekoo Dhar, Jotica Talwar and Neville Mobarakai

Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report

Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin is a rare but serious complication of the use of Nitrofurantoin.

Authors: Adrian F. Peall and Aidan Hodges

Fibromuscular dysplasia in an accessory renal artery causing renovascular hypertension: a case report

Renovascular hypertension is defined as hypertension caused by renal artery stenosis. The two main etiologies are atherosclerosis and fibromuscular dysplasia. Fibromuscular dysplasia in an accessory renal arte...

Authors: Abdel-Rauf Zeina, Wolfson Vladimir and Elisha Barmeir

Giant hepatocellular adenoma as cause of severe abdominal pain: a case report

The authors describe the case of a large hepatocellular adenoma diagnosed in a 30-year old woman who came to us complaining of acute pain in the upper abdominal quadrants. The patient had been taking an oral c...

Authors: Luigi Sandonato, Calogero Cipolla, Giuseppa Graceffa, Tommaso V. Bartolotta, Sergio Li Petri, Oriana Ciacio, Fabio Cannizzaro and Mario A. Latteri

Severe hypercalcaemia and lymphoma in an HTLV-1 positive Jamaican woman: a case report

Human T cell lymphotrophic virus type-1 infection is endemic in the Afro-Caribbean community in Britain, with carriage rates of about 3%. Although there is a long latency, carriers have a 1–5% chance of develo...

Authors: Veronica Lyell, Elham Khatamzas and Theresa Allain

Fluoroquinolone-associated tendinopathy: a case report

Fluoroquinolone-associated tendinopathy is well described. This adverse effect however does not appear to be widely known among medical practitioners. We hereby described a case of ciprofloxacin-associated ten...

Authors: Wan-Fai Ng and Michael Naughton

Congenital anterolateral tibial bowing and polydactyly: a case report

Congenital anterolateral bowing of the tibia is a rare deformity that may lead to pseudarthrosis and risk of fracture. This is commonly associated with neurofibromatosis type 1. In this report, we describe a 1...

Authors: Edmond G. Lemire

An unusual presentation of brucellosis, involving multiple organ systems, with low agglutinating titers: a case report

Brucellosis is a multi-system disease that may present with a broad spectrum of clinical manifestations. While hepatic involvement in brucellosis is not rare, it may rarely involve the kidney or display with c...

Authors: Farzin Khorvash, Ammar H. Keshteli, Mohaddeseh Behjati, Mansoor Salehi and Alireza Emami Naeini

Delayed presentation of an isolated gallbladder rupture following blunt abdominal trauma: a case report

Blunt injuries to the gallbladder occur rarely, and the incidence of isolated damage to the gallbladder is even smaller. We report a case of delayed presentation of isolated rupture of the gallbladder followin...

Authors: Jonathan Bainbridge, Hossam Shaaban, Nick Kenefick and Christopher P. Armstrong

Atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report

Severe hypertriglyceridaemia (HTG) is uncommon but most prevalent in subjects with type 2 diabetes mellitus (T2DM) and excess ethanol intake.

Authors: Ali I. Albahrani, Jannette Usher J., Eileen Marks, L. Ranganath and Alan Shenkin

Primary malignant melanoma of the oesophagus: a case report

Primary malignant melanoma of the oesophagus is a rare neoplasm comprising less than 0.2% of all primary oesophageal neoplasms. There are fewer than 250 reported cases in worldwide literature. Several reports ...

Authors: Justin Kelly, Mary Leader and Patrick Broe

Patent vitellointestinal duct with prolapse of inverted loop of small intestine: a case report

A wide variety of anomalies may occur as a result of the vitellointestinal duct (VID) failing to obliterate completely. Most reports on symptomatic VID focus on Meckel's diverticulum, while other anomalies are...

Authors: Prashant N. Mohite, Ashok M. Bhatnagar, Virsing P. Hathila and Jitendra H. Mistry

An impinging remnant meniscus causing early polyethylene failure in total knee arthroplasty: a case report

The management of patients with an apparently normal functional total knee arthroplasty (TKA) suffering from unexplained persistent pain and swelling is a challenging issue. The usual causes of pain after tota...

Authors: Rachid Saouti, Barend J. van Royen and Christiaan M. Fortanier