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  1. Lung involvement in inflammatory bowel diseases usually follows colitis. However, the time to lung involvement onset varies depending on the case, and pulmonary lesions are usually not parallel to exacerbation...

    Authors: Shouichi Okamoto, Kengo Koike, Mitsuaki Sekiya, Koichi Nishino, Tomoyasu Mimori and Kazuhisa Takahashi
    Citation: Journal of Medical Case Reports 2022 16:414
  2. We report a case of acute respiratory distress associated with a histological pattern of acute fibrinous and organizing pneumonia, and discuss the possible responsibility of flecainide therapy.

    Authors: Gauthier Moureau, Elies Zarrouk, Delphine Hoton, Franck Saint-Marcoux, Lidvine Boland, Vincent Haufroid and Philippe Hantson
    Citation: Journal of Medical Case Reports 2022 16:404
  3. A previously healthy young male of Southeast Asian descent presented with 6 weeks of fevers, cough, mucocutaneous ulcers, arthritis, and myalgias. Initial workup revealed positive Mycoplasma pneumoniae immunoglob...

    Authors: Jessica Hoey, Jenny Lue Solomon, Brandon Kim, Steven Carsons and Julie Nusbaum
    Citation: Journal of Medical Case Reports 2022 16:401
  4. Pfieffer syndrome is among the syndromes seen in the recognized variant of the FGFR2 gene. There are several conditions related to this variant and a very closely related condition is Crouzon syndrome. This ca...

    Authors: Karim P. Manji, Mariam Mngoya Massomo, Edna Samson Akyoo and McLean Abisai Luvinga
    Citation: Journal of Medical Case Reports 2022 16:399
  5. We report two similar cases of patients diagnosed with hemiballismus–hemichorea syndrome secondary to uncontrolled hyperglycemia. Both patients were treated at an inpatient rehabilitation center and made a sig...

    Authors: Luke Tsai, Benjamin Shekhtman, Ryan Stenquist, Ashley Schneider, Meilani Mapa, Edwin Amirianfar and David R. Gater
    Citation: Journal of Medical Case Reports 2022 16:398
  6. Lymphangiomas are rare benign malformations of the lymphatics that occur due to blockage of the lymphatic system during fetal development. They commonly occur in the neck and axilla, while involvement of the p...

    Authors: Hashan Pathiraja, Dhammike Rasnayake, Thilini Muthukumarana, Channa de Silva, Wasantha Sathkorala, Sandini Gunaratne, Shaman Rajindrajith and Sachith Mettananda
    Citation: Journal of Medical Case Reports 2022 16:397
  7. The use of checkpoint inhibitors has become increasingly important in the treatment of different cancers, including advanced muscle-invasive urothelial cancer and even in basal cell carcinoma. We present the c...

    Authors: Zsófia Küronya, Tímea Danyi, Tímea Balatoni, Gabriella Liszkay, Erika Tóth, Krisztina Biró and Lajos Géczi
    Citation: Journal of Medical Case Reports 2022 16:396
  8. Among the total reported cases of pancreatic duct adenocarcinomas, around 1–2.9% are adenosquamous carcinomas of the pancreas. Due to limited data, preoperative diagnosis is a great challenge for physicians, a...

    Authors: Daniel Paramythiotis, Filippos Kyriakidis, Eleni Karlafti, Triantafyllos Didangelos, Ilias-Marios Oikonomou, Anestis Karakatsanis, Christos Poulios, Eleni Chamalidou, Anastasios Vagionas and Antonios Michalopoulos
    Citation: Journal of Medical Case Reports 2022 16:395
  9. Ankyloglossia is commonly reported as one of the major causes of breastfeeding difficulty. There is a lack of research on infant growth and latching performance with clinical measures.

    Authors: Christyann Lima Campos Batista and Alex Luiz Pozzobon Pereira
    Citation: Journal of Medical Case Reports 2022 16:394
  10. Perchloroethylene is a colorless, strong-smelling substance commonly used for dry cleaning. Liver and kidney toxicities and carcinogenicity are well-known occupational hazards caused by chronic perchloroethyle...

    Authors: Alessandro Tarditi, Leda Montalbano, Stefano Spina, Francesco Marrazzo, Giampaolo Casella, Paolo Schenardi, Tommaso Conti, Ilaria Angeli, Mauro Minoli, Roberto Fumagalli and Thomas Langer
    Citation: Journal of Medical Case Reports 2022 16:388
  11. Anesthesia-associated rhabdomyolysis is a rare complication of surgery that causes postoperative myalgia, weakness, and potential renal failure if not managed promptly. Predisposing conditions that may lead to...

    Authors: John Floridis and Ruth Barbour
    Citation: Journal of Medical Case Reports 2022 16:387
  12. We describe a case of symptomatic bradycardia resulting from ivabradine toxicity by measurement of ivabradine levels, of which there are limited reports in the literature.

    Authors: Kavisha Singh, Muthukumar R. Alagarraju, Carl E. Wolf, Justin L. Poklis, Nitin Kulkarni, William Tharpe and Parag H. Joshi
    Citation: Journal of Medical Case Reports 2022 16:392
  13. Up to 50% of cases of Shiga-toxin-producing Escherichia coli hemolytic uremic syndrome occur in adults, and the clinical presentation is variable. Microbiological analyses must be performed in all patients with t...

    Authors: Elia Rigamonti, Tecla Bonora, Mariangela Ventresca and Pietro Cippà
    Citation: Journal of Medical Case Reports 2022 16:384
  14. Molecular-targeted agents used as a treatment for cancer can cause some rare and serious adverse events such as, delayed wound healing. Depending on the anticancer drug used, temporary withdrawal may be recomm...

    Authors: Mioko Matsuo, Kazuki Hashimoto, Rina Jiromaru and Takashi Nakagawa
    Citation: Journal of Medical Case Reports 2022 16:383
  15. Lightning strike is a rare but dramatic cause of injury. Patients admitted to intensive care units (ICUs) with lightning strike frequently have a high mortality and significant long-term morbidity related to a...

    Authors: Erik Roman-Pognuz, Edoardo Moro, Elisabetta Macchini, Edoardo Di Paolo, Kenneth Pesenti, Umberto Lucangelo, Rossana Bussani, Elisa Baratella, Tommaso Pellis and Giuseppe Ristagno
    Citation: Journal of Medical Case Reports 2022 16:391
  16. There is currently no information on the anatomical risk factors for splenic artery aneurysm rupture, specifically the location or size of the lesion; therefore, reporting this entity to obtain data and ultima...

    Authors: Ahmad Hosseinzadeh, Reza Shahriarirad, Vahid Asgharzadeh Majdazar, Mohammad Moeini Farsani and Seyed Mohammad Kazem Tadayon
    Citation: Journal of Medical Case Reports 2022 16:382
  17. Psychotic symptoms associated with hypothyroidism, also known as “myxedema psychosis,” are a treatable cause of psychosis often associated with complete recovery. While most cases receive both thyroxine and a ...

    Authors: Eric C. Chan
    Citation: Journal of Medical Case Reports 2022 16:378
  18. 5p deletion syndrome is known as cri-du-chat syndrome, but there are no reports on congenital diaphragmatic hernia complications associated with it.

    Authors: Tomomi Kotani, Takafumi Ushida, Noriyuki Nakamura, Kenji Imai, Yukako Iitani, Sho Tano, Shigenori Iwagaki, Yuichiro Takahashi, Miharu Ito, Masahiro Hayakawa and Hiroaki Kajiyama
    Citation: Journal of Medical Case Reports 2022 16:390
  19. Atrial fibrillation is one of the most common arrhythmias. The main thrombotic complication of arterial fibrillation is ischemic stroke, but it can also cause acute renal infarction from embolization. The low ...

    Authors: Tao Ge, ZhengCai Zhu, Jinfeng Wang, Wenjiao Zhou, Evelyn J. Song and Shengxing Tang
    Citation: Journal of Medical Case Reports 2022 16:381
  20. Cavernous venous malformation is an uncommon entity that occurs in around 0.5% of the general population. Cerebellar cavernous venous malformation accounts for 1.2–11.8% of intracranial cavernous venous malfor...

    Authors: A. H. Ibrahim, N. Mohamad, T. A. Mohd Yusof Rasid and M. S. Abdullah
    Citation: Journal of Medical Case Reports 2022 16:380
  21. Pulmonary arterial hypertension is a progressive, debilitating condition characterized by increased resistance in the pulmonary arterial circulation. Current treatments for pulmonary arterial hypertension incl...

    Authors: Mariangela Lattanzio, Marco Ferrari, Stefano Martini, Francesca Ceriani, Andrea Imporzani, Franca Marino, Roberto De Ponti and Marco Cosentino
    Citation: Journal of Medical Case Reports 2022 16:385
  22. An acute abdomen can have a variety of causes. A commonly missed cause of abdominal pain is direct substance abuse and its sequelae. The use of methamphetamine is rising in the United States resulting in signi...

    Authors: Surendra Sapkota, Sarah David, Sandipa Sharma, Suraj Shrestha and Abhishek Kalla
    Citation: Journal of Medical Case Reports 2022 16:379
  23. Sjogren’s syndrome, an autoimmune disease of the exocrine glands, results in keratoconjunctivitis sicca, xerostomia, and dental caries. It is often overlooked, considered by clinicians to be a benign disease. ...

    Authors: Maen D. Abou Ziki, Roy Taoutel, Julian C. Hong and David N. Podell
    Citation: Journal of Medical Case Reports 2022 16:374
  24. Flexor tendon sheath infection may be due to trauma, laceration, or bites, commonly directly inoculating the sheath. Kanavel cardinal signs in flexor tendon sheath infection cases consist of symmetrical swelli...

    Authors: Gregorius Batara Putra Setia Sutardi, De Is M. Rizal Chaidir and Yoyos Dias Ismiarto
    Citation: Journal of Medical Case Reports 2022 16:373
  25. One of the most common types of congenital adrenal hyperplasia is an autosomal recessive disorder with 21-hydroxylase deficiency. The classical form, defined by cortisol insufficiency, is accompanied by prenat...

    Authors: Nada Dehneh, Rami Jarjour, Sahar Idelbi, Assad Alibrahem and Sahar Al Fahoum
    Citation: Journal of Medical Case Reports 2022 16:371
  26. Collapsing glomerulopathy, characterized by marked hypertrophy and hyperplasia of the podocytes with eventual collapse of the glomerular tuft, is an important cause of end-stage renal disease. Among the many c...

    Authors: Matas Orentas, Nilam Patel, Roger Rodby and Sobia Hassan
    Citation: Journal of Medical Case Reports 2022 16:370
  27. Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episode syndrome is a rare mitochondrial genetic disorder that can present with a variety of clinical manifestations, including stroke, hearing...

    Authors: Ahmad F. Alenezi, Mariam A. Almelahi, Feten Fekih-Romdhana and Haitham A. Jahrami
    Citation: Journal of Medical Case Reports 2022 16:361
  28. Due to indels in the β-globin gene, patients with β-thalassemia major exhibit a range of severity, with genotype β0β0 > β0β+ > β+β+, according to the production level of the β-globin chain. More than 300 mutation...

    Authors: Waseem Chauhan, Rafat Fatma, Zeeba Zaka-ur-Rab and Mohammad Afzal
    Citation: Journal of Medical Case Reports 2022 16:362
  29. Peyronie’s disease is a chronic inflammatory condition of the corpora cavernosa characterized by the formation of plaque in the tunica albuginea, which results in penile deformity. Conservative medical approac...

    Authors: Gianni Paulis and Giovanni De Giorgio
    Citation: Journal of Medical Case Reports 2022 16:359
  30. Epidermolysis bullosa is a rare inherited connective tissue disorder compromising cellular junctions. Blister formation is the first manifestation of epidermolysis bullosa. As cellular adhesion is affected, it...

    Authors: Soheil Dehghani, Boshra Akbarzadeh Pasha, Amirali Karimi and Azadeh Afshin
    Citation: Journal of Medical Case Reports 2022 16:358
  31. Oral manifestations of coronavirus disease 2019 (COVID-19), including ulcers, herpetiform lesions, macules, and petechiae, among others, are becoming increasingly recognized, but there is little guidance on th...

    Authors: Saira Chaughtai, Zeeshan Chaughtai and Arif Asif
    Citation: Journal of Medical Case Reports 2022 16:367
  32. We present this case to draw attention to the importance of early diagnosis in terms of life-saving, noting that greater awareness is important among healthcare professionals. Our patient developed neuroleptic...

    Authors: Chee Keong Chang, Alvin Oliver Payus, Malehah Mohd Noh, Meryl Grace Lansing, Doreen Sumpat, Sooth Jiun Andrea Lu and Boon Teong Yew
    Citation: Journal of Medical Case Reports 2022 16:366
  33. Outbreaks of methanol poisoning have been described in the medical literature in different regions around the world. Even though in Saudi Arabia a few outbreaks of methanol poisoning have occurred, they remain...

    Authors: Rawan Eskandrani, Khalid Almulhim, Abdulla Altamimi, Abeer Alhaj, Shahd Alnasser, Laale Alawi, Eman Aldweikh, Khalid Alaufi and Bandr Mzahim
    Citation: Journal of Medical Case Reports 2022 16:357
  34. Primary squamous cell carcinoma of the thyroid is a very rare malignancy with aggressive growth and poor prognosis. There is currently no consensus for treatment modality, however, most patients with primary s...

    Authors: Meng-Lun Hsieh, Brian M. Besch, Jo Elle G. Peterson and Christina Henson
    Citation: Journal of Medical Case Reports 2022 16:364
  35. Pancreatic panniculitis is characterized by subcutaneous fat necrosis and is a rare presentation of an underlying pancreatic disease, appearing in approximately 2–3% of all patients with a pancreatic disease. ...

    Authors: S. M. Haenen, J. A. M. G. Tol, S. C. J. van Steen, O. R. Busch, A. Farine Sarasqueta, S. Roshani, A. Wolkerstorfer, M. M. D. van der Linden, J. W. Wilmink, H. C. Post and M. G. Besselink
    Citation: Journal of Medical Case Reports 2022 16:356
  36. Immune checkpoint inhibitors avoid inhibition of T-cell responses, upregulating antitumor immune response. Moreover, a dysregulation with hyperactive immune response can be caused, some of them underdiagnosed....

    Authors: Jaime Rubio-Perez, Ángel Ricardo Rodríguez-Perez, María Díaz-Blázquez, Victor Moreno-García and Manuel Dómine-Gómez
    Citation: Journal of Medical Case Reports 2022 16:365
  37. As the coronavirus disease 2019 infections are still ongoing, there is an increasing number of case reports and case series with various manifestations of life-threatening multisystem inflammatory syndrome in ...

    Authors: Alije Keka-Sylaj, Atifete Ramosaj, Arbana Baloku, Qëndresa Beqiraj and Petrit Gjaka
    Citation: Journal of Medical Case Reports 2022 16:352
  38. Mitochondrial neurogastrointestinal encephalopathy is a rare multisystem autosomal recessive disease caused by mutations in the TYMP gene, that encodes for thymidine phosphorylase. Mitochondrial neurogastrointest...

    Authors: Zaraq Rashid Khan, Alvina Karam, Mian Ayaz ul Haq, Aleena Aman and Ahmad Sharjeel Karam
    Citation: Journal of Medical Case Reports 2022 16:363
  39. Lafora disease is a rare genetic disorder involving glycogen metabolism disorder. It is inherited by autosomal recessive pattern presenting as a progressive myoclonus epilepsy and neurologic deterioration begi...

    Authors: Naim Zeka, Leonore Zogaj, Abdurrahim Gerguri, Ramush Bejiqi, Ragip Ratkoceri, Arlinda Maloku, Aferdita Mustafa, Labinot Shahini and Jeton Maxharaj
    Citation: Journal of Medical Case Reports 2022 16:360
  40. Hematomas that slowly increase in size for more than 1 month after the initial hemorrhage are referred to as chronic expanding hematomas. Chronic expanding hematoma can also occur after radiosurgery; however, ...

    Authors: Yojiro Ishikawa, Takaya Yamamoto, Rei Umezawa, Noriyoshi Takahashi, Kazuya Takeda, Yu Suzuki and Keiichi Jingu
    Citation: Journal of Medical Case Reports 2022 16:353

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