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  1. Coronavirus disease 2019 (COVID-19) is a global pandemic. The disease, typically characterized by bilateral pulmonary infiltrates and profound elevation of inflammatory markers, can range in severity from mild...

    Authors: Dmitriy A. Gagarkin, Keith E. Dombrowski, Keyur B. Thakar and John C. DePetrillo

    Citation: Journal of Medical Case Reports 2021 15:219

    Content type: Case report

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  2. The outbreak of coronavirus disease 2019 (COVID-19) started in December 2020, and is a global problem now. There are several sets of established data regarding computed tomography (CT) findings in COVID-19 pne...

    Authors: Afshin Rakhsha, Zahra Mahboubi-Fooladi and Anya Jafari

    Citation: Journal of Medical Case Reports 2021 15:218

    Content type: Case report

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  3. The median sternotomy approach in sleeve pneumonectomy enables diseased lung ventilation in selected cases, which may reduce the difficulty in achieving anastomosis under intubation of the left main bronchus. ...

    Authors: Hirotoshi Suzuki, Masafumi Noda, Tatsuaki Watanabe, Yasushi Matsuda, Yasushi Hoshikawa and Yoshinori Okada

    Citation: Journal of Medical Case Reports 2021 15:205

    Content type: Case report

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  4. Failed aortofemoral and femoropopliteal bypass grafts in the lower extremity artery usually result in acute limb ischemia. Endovascular treatment and surgical revascularization have been reported for limb salv...

    Authors: Tatsuo Haraki, Taichi Kondo, Izaya Kamei and Takahiro Tanabe

    Citation: Journal of Medical Case Reports 2021 15:204

    Content type: Case report

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  5. Sirenomelia, also called mermaid syndrome, is a rare lethal multi-system congenital deformity with an incidence of one in 60,000–70,000 pregnancies. Sirenomelia is mainly characterized by the fusion of lower l...

    Authors: Asiyeh Shojaee, Firooze Ronnasian, Mahdiyeh Behnam and Mansoor Salehi

    Citation: Journal of Medical Case Reports 2021 15:217

    Content type: Case report

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  6. Because of the rarity of primary hepatic lymphomas, diagnosis of this disease entity may often be difficult, and performing a liver biopsy is the only way to establish a definitive diagnosis. Recently, endosco...

    Authors: Kenichiro Nishikawa, Koji Katsuta, Syota Tanaka, Kodai Fujibe, Aiji Hattori, Yasunori Shiono, Michiaki Oiwa and Shimpei Matsusaki

    Citation: Journal of Medical Case Reports 2021 15:199

    Content type: Case report

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  7. Thoracoscopic segmentectomy of the lateral and posterior basal segments is extremely technically challenging. Appropriate segmentectomy requires exposure and recognition of the branches of the bronchi and pulm...

    Authors: Shota Mitsuboshi, Hiroaki Shidei, Akihiro Koen, Hideyuki Maeda, Hiroe Aoshima, Tamami Isaka and Masato Kanzaki

    Citation: Journal of Medical Case Reports 2021 15:196

    Content type: Case report

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  9. Routine myomectomy at the time of cesarean section has been condemned in the past due to fear of uncontrolled hemorrhage and peripartum hysterectomy. It is still a topic of debate worldwide. However, in recent...

    Authors: Priyanka Garg and Romi Bansal

    Citation: Journal of Medical Case Reports 2021 15:193

    Content type: Case report

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  10. Thromboangiitis obliterans or Buerger’s disease is a form of peripheral vascular disease in young male smokers. The involvement of the intestine occurs in only about 2% of the cases, when they may present as a...

    Authors: Swastik Sourav Mishra, Tushar Subhadarshan Mishra, Suvradeep Mitra and Pankaj Kumar

    Citation: Journal of Medical Case Reports 2021 15:215

    Content type: Case report

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  11. Immune checkpoint inhibitors have recently become widely used for the management of advanced cancer patients. During the development of immune checkpoint inhibitors (ICPIs), it was quickly recognized that they...

    Authors: Fumi Kikuchi, Takanobu Saheki, Hitomi Imachi, Toshihiro Kobayashi, Kensaku Fukunaga, Tomohiro Ibata, Seisuke Sato, Natsuki Ban, Jingya Lyu, Salimah Japar and Koji Murao

    Citation: Journal of Medical Case Reports 2021 15:214

    Content type: Case report

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  12. Vertical transmission of coronavirus disease 2019 (COVID-19) from mother to newborn infant is doubtful, and very little is known about disease severity and neonatal outcome.

    Authors: Roya Farhadi, Shahrokh Mehrpisheh, Vajiheh Ghaffari, Mohammadreza Haghshenas and Aghdas Ebadi

    Citation: Journal of Medical Case Reports 2021 15:213

    Content type: Case report

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  13. Dermatologic toxicity is a very common immune-related adverse event (irAE) for patients with melanoma who are receiving immune checkpoint inhibitor therapy (ICI). Concurrent skin infection, such as in the case...

    Authors: Mingjia Li, Natalie Spaccarelli, Kari Kendra, Richard C. Wu and Claire Verschraegen

    Citation: Journal of Medical Case Reports 2021 15:212

    Content type: Case report

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  14. Homologous recombination deficiency is a marker of response to poly(ADP-ribose) polymerase inhibitors in different cancer types including ovary, prostate, and pancreatic cancer. To date, no report about poly(A...

    Authors: Rosa Montero-Macias, Meriem Koual, Céline Crespel, Marie Aude Le Frére-Belda, Hélène Blons Hélène, Huyen-Thu Nguyen-Xuan, Simon Garinet, Géraldine Perkins, Vincent Balay, Catherine Durdux, Marie Florin, Hélène Péré and Anne-Sophie Bats

    Citation: Journal of Medical Case Reports 2021 15:210

    Content type: Case report

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  15. Methimazole (MMI) is the treatment of choice for patients with Graves’ disease. The major drawback of this treatment is the relapse of hyperthyroidism in half of the patients after discontinuation of the recom...

    Authors: Fereidoun Azizi, Atieh Amouzegar and Hengameh Abdi

    Citation: Journal of Medical Case Reports 2021 15:189

    Content type: Case report

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  16. Coronavirus disease 2019 has become a health problem spreading worldwide with pandemic characteristics since March 2020. Post coronavirus disease 2019 symptoms are more frequent than initially expected, with f...

    Authors: Andreas Rembert Koczulla, Antje Stegemann, Rainer Gloeckl, Sandra Winterkamp, Bernd Sczepanski, Tobias Boeselt, Jan Storre and Michael Dreher

    Citation: Journal of Medical Case Reports 2021 15:211

    Content type: Case report

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  17. Dementia is among the most common chronic noncommunicable neurodegenerative diseases. In the long term, it causes disability and loss of autonomy and independence. It is estimated that there are 35.6 million p...

    Authors: Letícia Zanetti Marchi, Rayssa Gabriela Dantas Ferreira, Gabriella Nayara Siqueira de Lima, Jessyca Alves Silvestre da Silva, Daniel Marinho Cezar da Cruz, Bernardino Fernandez-Calvo and Suellen Mary Marinho dos Santos Andrade

    Citation: Journal of Medical Case Reports 2021 15:185

    Content type: Case report

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  18. Aripiprazole is a third-generation atypical antipsychotic drug that acts as a stabilizer of the dopaminergic and serotonergic system. As partial agonist of the dopamine (D2) and serotonin (5-HT1A) receptors, ...

    Authors: Rosaria Nardello, Fulvio Guccione, Claudia Gliubizzi, Antonio Marino, Mariarita Capizzi and Salvatore Mangano

    Citation: Journal of Medical Case Reports 2021 15:209

    Content type: Case report

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  19. Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome (Online Mendelian Inheritance in Man [OMIM] #277000) is a congenital condition characterized by the total or partial agenesis of vagina and uterus. Agenesis can b...

    Authors: Domenico Dell’Edera, Arianna Allegretti, Mario Ventura, Ludovica Mercuri, Angela Mitidieri, Giacinto Cuscianna, Annunziata Anna Epifania, Elisena Morizio, Melissa Alfonsi and Paolo Guanciali-Franchi

    Citation: Journal of Medical Case Reports 2021 15:208

    Content type: Case report

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  20. Although central nervous system tumors are the most common etiology of malignancies in the pediatric age group, choroid plexus carcinomas are rare, with an annual incidence rate of 0.10 per 100,000 children.

    Authors: Patel Zeeshan Jameel, Ashish Varma, Pooja Kumari, Keta Vagha, Jayant Vagha and Sachin Damke

    Citation: Journal of Medical Case Reports 2021 15:184

    Content type: Case report

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  21. Dermatofibrosarcoma protuberans (DFSP) is a rare skin fibroblastic tumor, with a high rate of recurrence. The treatment of DFSP is generally surgical, and wide local excision is the mainstay of surgical treatm...

    Authors: Fedele Lembo, Liberato Roberto Cecchino, Domenico Parisi and Aurelio Portincasa

    Citation: Journal of Medical Case Reports 2021 15:180

    Content type: Case report

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  22. This report describes the clinical course of choroidal neovascular membrane (CNV) in West Nile virus-associated chorioretinitis.

    Authors: Roberta Zito, Tommaso Micelli Ferrari, Luigi Di Pilato, Massimo Lorusso, Anna Ferretta, Luisa Micelli Ferrari and Massimo Accorinti

    Citation: Journal of Medical Case Reports 2021 15:206

    Content type: Case report

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  23. Classic Kaposi sarcoma (CKS) is a vascular sarcoma associated with human herpesvirus 8 (HHV-8), which is known to be more common in Mediterranean elderly men and is characterized by indolent clinical behavior....

    Authors: Jing Zhou, Xiaoping Shen, Xiaodong Wang, Kun Xiao, Yu Cao and Yanping Jiang

    Citation: Journal of Medical Case Reports 2021 15:179

    Content type: Case report

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  24. Sarcoidosis is pathologically characterized by the formation of non-necrotizing epithelioid cell granulomas. However, pathological findings of patients with sarcoidosis have rarely revealed necrosis. We report...

    Authors: Yosuke Miyashita, Munechika Hara, Shin-ichiro Iwakami, Hironari Matsuda, Naoko Iwakami and Kazuhisa Takahashi

    Citation: Journal of Medical Case Reports 2021 15:178

    Content type: Case report

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  25. Abdominal aortic aneurysm and acute appendicitis occur relatively frequently in elderly patients. However, the co-occurrence of the two pathologies is very rare and serious.

    Authors: Rubén Peña, Sergio Valverde, José A. Alcázar, Paloma Cebrián, José Ramón González-Porras and Francisco S. Lozano

    Citation: Journal of Medical Case Reports 2021 15:203

    Content type: Case report

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  26. Androgen insensitivity syndrome is a rare X-linked disorder of sex development, caused by mutations in the androgen receptor. In this case, a 13-year-old child, reared as female, presenting for primary amenorr...

    Authors: Stephanie Farah, Dana El Masri and Kamal Hirbli

    Citation: Journal of Medical Case Reports 2021 15:202

    Content type: Case report

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  27. Malignant hyperthermia (MH) is a rare genetic disease characterized by the development of very serious symptoms, and hence prompt and appropriate treatment is required. However, postoperative MH is very rare, ...

    Authors: Natsumi Miyazaki, Takayuki Kobayashi, Takako Komiya, Toshio Okada, Yusuke Ishida, Hidekimi Fukui, Yukihiko Ogihara and Hiroyuki Uchino

    Citation: Journal of Medical Case Reports 2021 15:201

    Content type: Case report

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  29. Cold agglutinin disease can cause the agglutination of red blood cells and hemolytic anemia due to cold temperature. Herein, we report a case of progressive hemolytic anemia due to cold agglutinin disease duri...

    Authors: Yosuke Kawai, Miyoshi Deguchi, Naoko Mizouchi, Satoru Yoshida, Ken Kumagai and Yasuo Hirose

    Citation: Journal of Medical Case Reports 2021 15:169

    Content type: Case report

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  30. Thoracic endovascular aortic repair (TEVAR) is the gold standard for surgical management of descending thoracic aortic pathology. Depending on the anatomy, TEVAR often requires deployment across the origin of ...

    Authors: Kevin G Kim, Anthony N Grieff and Saum Rahimi

    Citation: Journal of Medical Case Reports 2021 15:168

    Content type: Case report

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  32. Double adenomas (DA) represents a distinct clinical entity of primary hyperparathyroidism (PHPT). DA may follow various embryologic distribution patterns and could be supernumerary and/or ectopic.

    Authors: Georgios Tzikos, Michael Polyzonis, Konstantinos Milias, Stefanos Milias, Ioannis Passos, Konstantinos Ioannidis, Nektaria-Dimitra Doutsini, Georgios Chatzoulis and Panagiotis Spyridopoulos

    Citation: Journal of Medical Case Reports 2021 15:198

    Content type: Case report

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  33. Hidradenoma papilliferum is a rare benign neoplasm arising from apocrine glands. It occurs commonly on the anogenital region of middle-aged women. It usually presents as a slow growing, solitary asymptomatic, ...

    Authors: Ozer Birge, Mehmet Sait Bakır, Ceyda Karadag, Zivar Eldarova and Tayup Simsek

    Citation: Journal of Medical Case Reports 2021 15:162

    Content type: Case report

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  34. Thalassemia is an inherited autosomal recessive blood disorder causing abnormal formation of hemoglobin, known as a syndrome of anemia with microcytic erythrocytes. It is the most common genetic disorder world...

    Authors: Daniel Oren, Amiel A. Dror, Tania Bramnik, Eyal Sela, Igal Granot and Samer Srouji

    Citation: Journal of Medical Case Reports 2021 15:197

    Content type: Case report

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  35. We report a unique case of synchronous sacrococcygeal chordoma in association with rectal invasive adenocarcinoma. Retrorectal tumors are a rare disease caused by a variety of pathologies. To our knowledge, no...

    Authors: Jaffar Alshahri, Mohammed Alshehri, Aminah Alnafesa, Mohammed Widinly, Tariq Alzaid, Saleh Alsulaimani and Alaa Abduljabbar

    Citation: Journal of Medical Case Reports 2021 15:195

    Content type: Case report

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  36. Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiologic entity characterized by headaches, altered mental status, seizures, visual loss, and a characteristic imaging pattern in brain magne...

    Authors: Goar Egoryan, Ricardo Murguia-Fuentes, Mohamed Agab, Nagwa Abou-Ghanem, Maria Adriana Yanez-Bello, Bimatshu Pyakuryal, Daniela Patricia Trelles-Garcia, Rami Ibrahim, Dorota Filipiuk, Adi Gidron and Guillermo Rodriguez-Nava

    Citation: Journal of Medical Case Reports 2021 15:161

    Content type: Case report

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  37. Adenoid cystic carcinoma (ACC) is a rare malignant tumor involving mostly the head and neck region, and frequently the salivary glands. The development of lung metastasis after treatment of the primary tumor i...

    Authors: Daijiro Kobayashi, Takanori Abe, Jun-ichi Saitoh, Takahiro Oike, Hiro Sato, Atsushi Musha, Tatsuji Mizukami, Tsuneo Shimizu, Takashi Nakano and Tatsuya Ohno

    Citation: Journal of Medical Case Reports 2021 15:156

    Content type: Case report

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  38. Malignant tumors, such as acute leukemia and solid cancers, frequently cause disseminated intravascular coagulation. However, cases of disseminated intravascular coagulation as a complication of bursitis were ...

    Authors: Taisuke Hamada, Tasuku Nishihara, Yosuke Mizuno, Teruki Kidani, Hiroki Tokiwa, Naoki Abe, Keisuke Sekiya, Sakiko Kitamura, Yasushi Takasaki, Hiromasa Miura and Toshihiro Yorozuya

    Citation: Journal of Medical Case Reports 2021 15:155

    Content type: Case report

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  39. Esophageal involvement and Horner’s syndrome are rare manifestations of breast cancer distant metastases that can pose a significant challenge in diagnosis and treatment. In addition to the more aggressive beh...

    Authors: Sumadi Lukman Anwar, Widya Surya Avanti, Lina Choridah, Ery Kus Dwianingsih, Herjuna Hardiyanto and Teguh Aryandono

    Citation: Journal of Medical Case Reports 2021 15:194

    Content type: Case report

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  40. Mayfield skull clamps are widely used and indispensable in current neurosurgery. Complications such as skull fractures or intracranial hematoma from using a Mayfield skull clamp have largely been reported in t...

    Authors: Takeo Furuya, Masashi Yamazaki, Tetsuharu Nemoto, Akihiko Okawa and Seiji Ohtori

    Citation: Journal of Medical Case Reports 2021 15:154

    Content type: Case report

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  41. Acute severe asthma is a life-threatening medical emergency. Characteristics of asthma include increased airway resistance and dynamic pulmonary hyperinflation that can manifest in dangerous levels of hypercap...

    Authors: Rossella Esposito, Irene Esposito, Francesco Imperatore, Giovanni Liguori, Fabrizio Gritti, Chiara Cafora, Paolo Francesco Marsilia and Maria De Cristofaro

    Citation: Journal of Medical Case Reports 2021 15:200

    Content type: Case report

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  42. Blocking the programmed death 1 pathway by immune checkpoint inhibitors induces dramatic antitumor activity in patients with malignant tumors. However, the clinical response to immune checkpoint inhibitors rem...

    Authors: Rishu Takimoto, Takashi Kamigaki, Takuji Gotoda, Toshimi Takahashi, Sachiko Okada, Hiroshi Ibe, Eri Oguma and Shigenori Goto

    Citation: Journal of Medical Case Reports 2021 15:191

    Content type: Case report

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  43. Although drug-induced interstitial pneumonia is a well-known adverse side-effect of cancer chemotherapy, the disease is difficult to detect in the early phase. We report a case of oxaliplatin-induced interstit...

    Authors: Yasuyuki Taooka, Hiroki Yoke and Junya Inata

    Citation: Journal of Medical Case Reports 2021 15:153

    Content type: Case report

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  44. Appendicitis following trauma is a well-documented sequela of blunt trauma to the abdomen, while appendiceal transection following trauma is extremely rare. Literature reports have documented appendicitis and ...

    Authors: Kanika Sharma, Shreya Tomar, Shilpa Sharma and Minu Bajpai

    Citation: Journal of Medical Case Reports 2021 15:192

    Content type: Case report

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  45. Raoultella Planticola is a facultative anaerobic, gram-negative, water- and soil-dwelling rod bacterium rarely reported as a cause of human disease. However, the number of reported R. planticola infections is gro...

    Authors: David Blihar, Phenyo Phuu, Svetlana Kotelnikova and Edward Johnson

    Citation: Journal of Medical Case Reports 2021 15:152

    Content type: Case report

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  46. Pseudo-Wellens syndrome is a rare entity characterized by the presence of electrocardiogram (ECG) changes of Wellens syndrome but without the stenosis of the left anterior descending (LAD) coronary artery. In ...

    Authors: Teressa Reanne Ju, Ilhwan Yeo, Gregory Pontone and Reema Bhatt

    Citation: Journal of Medical Case Reports 2021 15:151

    Content type: Case report

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  47. The incidence of ectopic kidneys is 1:12,000 clinically and 1:900 postmortem. Patients with pelvic mal-rotated kidneys are more susceptible to recurrent urinary tract infections, recurrent renal stones, and re...

    Authors: Hussam S. Khougali, Omer Ali Mohamed Ahmed Alawad, Nicholas Farkas, Mohammed Mahgoub Mirghani Ahmed and Alnasri Mohammed Abuagla

    Citation: Journal of Medical Case Reports 2021 15:181

    Content type: Case report

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  49. Central hyperthyroidism is a rare form of hyperthyroidism caused by thyrotrope pituitary adenomas. It is characterized by elevated thyroid-stimulating hormone alongside high thyroxine and triiodothyronine. Goi...

    Authors: David George Jackson, John Parker and Thomas Cummings

    Citation: Journal of Medical Case Reports 2021 15:173

    Content type: Case report

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  50. Umbilical hernias are a frequent and well-known pathology in children or adults. Congenital umbilical hernias are commonly diagnosed in childhood, and in adulthood such a hernia is usually acquired. Umbilical ...

    Authors: Friday Saidi, Bakari Rajab, Lameck Chinula, Nomsa Kafumba, Maganizo Chagomerana and Jennifer H. Tang

    Citation: Journal of Medical Case Reports 2021 15:187

    Content type: Case report

    Published on:

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Journal of Medical Case Reports

ISSN: 1752-1947