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  1. Syndrome of inappropriate antidiuretic hormone secretion can be caused by arginine-vasopressin-producing tumors or enhanced arginine vasopressin secretion from the posterior pituitary gland due to central nerv...

    Authors: Masanori Hasebe, Jun Shirakawa, Daisuke Miyashita, Rieko Kunishita, Mayu Kyohara, Tomoko Okuyama, Yu Togashi and Yasuo Terauchi

    Citation: Journal of Medical Case Reports 2021 15:390

    Content type: Case report

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  2. Cystoid macular edema is a rare, vision-threatening side effect of the taxane family of anticancer agents. There is no established treatment or standard treatment protocol for taxane-related cystoid macular ed...

    Authors: Mitsuru Otsubo, Reiko Kinouchi, Takayuki Kamiya and Akitoshi Yoshida

    Citation: Journal of Medical Case Reports 2021 15:355

    Content type: Case report

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  3. The clinical history and outcomes of coronavirus disease 2019 among people not hospitalized is not yet well characterized. To better inform clinical evaluation, we set out to characterize the natural history o...

    Authors: Stefania Dzieciolowska, Oumeet Ravi and Roland Grad

    Citation: Journal of Medical Case Reports 2021 15:393

    Content type: Research article

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  4. The topic of natural immunity related to severe acute respiratory syndrome coronavirus 2 remains controversial. Although evidence suggests postinfection immunity can be achieved, there have been reported cases...

    Authors: Nimrah Bader, Mahmood Khattab and Fahmi Farah

    Citation: Journal of Medical Case Reports 2021 15:392

    Content type: Case report

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  5. Hyperammonemic encephalopathy, a rare but fatal condition, is increasingly being reported as a possible complication of bariatric surgery. Here, we present a case of hyperammonemic encephalopathy, focusing on ...

    Authors: Nuphar Vinegrad, Orna Staretz-Chacham, Leonid Barski and Carmi Bartal

    Citation: Journal of Medical Case Reports 2021 15:385

    Content type: Case report

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  6. Clinical guidelines do not recommend further investigation for occult malignancy in the scenario of unprovoked venous thromboembolism in the absence of additional clinical features suggestive of malignancy. We...

    Authors: Kaitlin J. Mayne, Emma Lewis and Lewis Vickers

    Citation: Journal of Medical Case Reports 2021 15:354

    Content type: Case report

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  7. Morel-Lavallée lesions are posttraumatic, closed degloving injuries in which the skin and subcutaneous tissue are separated abruptly from superficial underlying fascia. This condition leads to an effusion cont...

    Authors: Claude Kasereka Masumbuko, Gabriel Kambale Bunduki and Mupenzi Mumbere

    Citation: Journal of Medical Case Reports 2021 15:383

    Content type: Case report

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  8. Hodgkin’s Lymphoma (HL) is a rare malignancy characterised histologically by the presence of Reed-Sternberg cells. Diagnosis of lymphomas can be difficult due to broad, non-specific presentations of disease, w...

    Authors: Anamika Banerjee, Kaljit Bhuller, Rajini Sudhir and Amrita Bajaj

    Citation: Journal of Medical Case Reports 2021 15:351

    Content type: Case report

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  9. Phlebosclerotic colitis is a rare condition with a high mortality. It has been seen almost exclusively in Asian patients who are ≥ 60 years old, with a slight male predominance. Although it predominantly affec...

    Authors: J. Mohigefer, P. Gómez-Millán and J. J. Borrero

    Citation: Journal of Medical Case Reports 2021 15:349

    Content type: Case report

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  10. Glomangioma is a benign tumor of mesenchymal origin, derived from the glomus body. It is responsible for the thermal regulation of the dermis. The occurrence of oncogenic osteomalacia related to glomangioma is...

    Authors: Camila R. Muniz, Gabriela A. M. Bezerra, Viviane C. da Silva, Priscilla M. F. Aguiar, Gunter Gerson, Catarina B. D’Alva and André A. A. Nunes

    Citation: Journal of Medical Case Reports 2021 15:348

    Content type: Case report

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  11. Coronavirus disease 2019 has been a public health threat and a worldwide emergency for more than a year. Unfortunately, many questions concerning the pathophysiology, management, and long-term side effects rem...

    Authors: Hussein Awada, Hasan Nassereldine and Adel Hajj Ali

    Citation: Journal of Medical Case Reports 2021 15:382

    Content type: Case report

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  12. The novel coronavirus, since its first identification in China, in December 2019, has shown remarkable heterogeneity in its clinical behavior. It has affected humans on every continent. Clinically, it has affe...

    Authors: Ahmed Maseh Haidary, Sarah Noor, Esmatullah Hamed, Tawab Baryali, Soma Rahmani, Maryam Ahmad, Farahnaz Erfani, Hashmatullah Azimi, Habib Ul Rahman Habib, Gul Ahmad Tahiri, Ramin Saadaat, Abdul Sami Ibrahimkhil, Esmatullah Esmat and Haider Ali Malakzai

    Citation: Journal of Medical Case Reports 2021 15:379

    Content type: Case report

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  13. Solitary pulmonary nodules are the most common incidental finding on chest imaging. Their management is very well defined by several guidelines, with risk calculators for lung cancer being the gold standard. S...

    Authors: George Tsaknis, Muhammad Naeem, Advitya Singh and Siddharth Vijayakumar

    Citation: Journal of Medical Case Reports 2021 15:347

    Content type: Case report

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  14. Atopic dermatitis is a chronic inflammatory skin disease associated with pruritus. Skin affected by atopic dermatitis not only shows a high percentage of Staphylococcus aureus colonization, but corneal barrier dy...

    Authors: Shuhei Kubota, Masaaki Nemoto, Yuki Sakaeyama, Chie Nakada, Masataka Mikai, Yutaka Fuchinoue, Kosuke Kondo, Naoyuki Harada and Nobuo Sugo

    Citation: Journal of Medical Case Reports 2021 15:373

    Content type: Case report

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  15. Klüver–Bucy syndrome is a rare and complex neurobehavioral cluster that occurs in humans and results from a temporal lobe lesion. It can be associated with a variety of causes. Stroke is a rarely reported caus...

    Authors: Alawi Aqel Al-Attas, Abdulrahman Yousef Aldayel, Tareq Hamad Aloufi and Nabil Biary

    Citation: Journal of Medical Case Reports 2021 15:346

    Content type: Case report

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  16. We present an unusual case of a patient who developed four melanomas within a few months of diagnosis with human immunodeficiency virus and commencement of highly active antiretroviral therapy therapy. The pat...

    Authors: Sharad P. Paul, Simon Briggs and Michael Hitchcock

    Citation: Journal of Medical Case Reports 2021 15:367

    Content type: Case report

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  17. Primary malignant melanoma of the esophagus is a rare form of mucosal melanoma with a poor prognosis. While immune checkpoint inhibitors have recently extended overall survival in metastatic melanoma, data on ...

    Authors: Takeshi Okamoto, Eriko Nakano and Teruo Yamauchi

    Citation: Journal of Medical Case Reports 2021 15:345

    Content type: Case report

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  18. Cavities are frequent manifestations of a wide variety of pathological processes involving the lung. There has been a growing body of evidence of coronavirus disease 2019 leading to a cavitary pulmonary disease.

    Authors: Goar Egoryan, Elise Hyser, Ammar H. Mushtaq, Maria Adriana Yanez-Bello, Daniela Patricia Trelles-Garcia, Harvey J. Friedman and Guillermo Rodriguez-Nava

    Citation: Journal of Medical Case Reports 2021 15:377

    Content type: Case report

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  19. Diaphragmatic hernia involves protrusion of abdominal contents into the thorax through a defect in the diaphragm. This defect can be caused either by developmental failure of the posterolateral foramina to fus...

    Authors: Konstantinos G. Spiridakis, Mathaios E. Flamourakis, Ioannis G. Gkionis, Eleni I. Kaloeidi, Anthoula I. Fachouridi, Styliani E. Konstantoulaki, Eleni S. Tsagkataki, Michail I. Giakoumakis, Emmamouil A. Vassilogiannakis, Georgios E. Kostakis and Manousos S. Christodoulakis

    Citation: Journal of Medical Case Reports 2021 15:372

    Content type: Case report

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  20. Encapsulating peritoneal sclerosis is a rare but potentially lethal complication of long-term peritoneal dialysis that is associated with significant morbidity and mortality. The occurrence of encapsulating pe...

    Authors: Saeed Mohammed AlZabali, Abdulkarim AlAnazi, Khawla A. Rahim and Hassan Y. Faqeehi

    Citation: Journal of Medical Case Reports 2021 15:366

    Content type: Case report

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  21. Bordetella trematum is unknown to most clinicians and microbiologists. However, this Gram-negative opportunistic bacterium can be responsible for ulcer superinfection but also bacteremia and sometimes death by se...

    Authors: M. Lacasse, K. Inyambo, A. Lemaignen, M. Mennecart, S. Gensburger, A. S. Valentin, L. Bernard and B. Fougère

    Citation: Journal of Medical Case Reports 2021 15:365

    Content type: Case report

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  22. Fibroids of the uterus are the most common benign pelvic tumors in women worldwide. Their diagnosis is usually not missed because of the widespread and well-established use of ultrasound in gynecological clini...

    Authors: Wiesener Viva, Dhanawat Juhi, Andresen Kristin, Mathiak Micaela, Both Marcus, Alkatout Ibrahim and Bauerschlag Dirk

    Citation: Journal of Medical Case Reports 2021 15:344

    Content type: Case report

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  23. The presence of isolated metachronous adrenal metastasis in patients with esophageal cancer is rare. There is significant controversy regarding the management of such patients. Adrenal metastasectomy has been ...

    Authors: Tarun Jindal, Ankush Sarwal, Pravin Pawar, M. Dhanalakshmi and Neeraj Subedi

    Citation: Journal of Medical Case Reports 2021 15:369

    Content type: Case report

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  24. The new coronavirus disease 2019 pandemic has spread throughout most of the world. Cerebral venous thrombosis is a rare thromboembolic disease that can present as an extrapulmonary complication in coronavirus ...

    Authors: Henry Robayo-Amortegui, Natalia Valenzuela-Faccini, Cesar Quecano-Rosas, Darlyng Zabala-Muñoz and Michel Perez-Garzon

    Citation: Journal of Medical Case Reports 2021 15:364

    Content type: Case report

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  25. Recurrent coronavirus disease 2019 (COVID-19) infection is an emerging problem and may prove to be one of the greatest problems in controlling the pandemic in the future. Recurrent infections can be due to rea...

    Authors: Jaya Garg, Jyotsna Agarwal, Anupam Das and Manodeep Sen

    Citation: Journal of Medical Case Reports 2021 15:363

    Content type: Case report

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  26. Disorders of sex development are anomalies in which the development of urogenital ridge is undifferentiated for the male and female child. Imaging plays a vital role in investigating the gross anatomy and asso...

    Authors: Mahamudu Ayamba Ali, Raymond Saa-Eru Maalman, Yaw Otchere Donkor and James Edward Mensah

    Citation: Journal of Medical Case Reports 2021 15:362

    Content type: Case report

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  27. The surgical management of esophageal atresia in extreme-low-birth-weight infants (< 1000 g) is challenging. We report on an extreme-low-birth-weight infant who was extremely preterm (510 g, 25 + 5 weeks) and ...

    Authors: Xiaoyan Feng, Ulrich Thomé, Holger Stepan, Martin Lacher and Richard Wagner

    Citation: Journal of Medical Case Reports 2021 15:361

    Content type: Case report

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  28. Aneurysm formation is a possible, but rare, complication of granulomatosis with polyangiitis, known as Wegener’s granulomatosis. Urgent diagnosis and therapy is very important because a ruptured aneurysm could...

    Authors: A. Gravos, K. Katsifa, P. Tselioti, V. Grammatikopoulou, K. Sakellaridis, S. Kanakaki, C. Tsapas, A. Destounis, H. Moschouris, I. Athanasiadou, F. Chatzivasiloglou, E. Ivanova and A. Prekates

    Citation: Journal of Medical Case Reports 2021 15:343

    Content type: Case report

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  29. Pleural effusion and pleuritis are uncommon manifestations of Mycobacterium avium complex pulmonary disease. Pleuritis caused by Mycobacterium avium complex pulmonary disease presenting as a solitary pulmonary no...

    Authors: Shigenari Nukaga, Hiroaki Murakami, Kazuma Yagi, Ryosuke Satomi, Takahiko Oyama, Arafumi Maeshima and Yoshitaka Oyamada

    Citation: Journal of Medical Case Reports 2021 15:342

    Content type: Case report

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  30. Superficial siderosis is a rare disease involving hemosiderin deposits on the surface of brain or spinal cord that are thought to cause clinical symptoms, which usually consist of cranial nerve dysfunction, ce...

    Authors: Tobias Braun, Maxime Viard, Tobias Struffert, Omar AlhajOmar, Mesut Yeniguen and Martin Juenemann

    Citation: Journal of Medical Case Reports 2021 15:353

    Content type: Case report

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  31. Since its debut recognition in 1981, human immunodeficiency virus/acquired immunodeficiency syndrome has affected over 77 million people and has resulted in premature cessation of 35.4 million lives worldwide....

    Authors: Pedro Pallangyo, Jalack Millinga, Happy Swai, Naairah R. Hemed, Zabela Mkojera, Silvia Mosha, Marcelina Granima, Smita Bhalia, Yona Gandye and Mohamed Janabi

    Citation: Journal of Medical Case Reports 2021 15:341

    Content type: Case report

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  32. We diagnosed a clinical case of pulmonary infection involving Mycobacterium tuberculosis and Tropheryma whipplei in a patient with acute respiratory distress syndrome. The diagnosis was assisted by metagenomic ne...

    Authors: Binghua Zhu, Jing Tang, Rong Fang, Xuejie Fei, Qing Wang, Wenqing Wang, Xueqin Wu, Chao Liu and Qian Wang

    Citation: Journal of Medical Case Reports 2021 15:359

    Content type: Case report

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  33. Uterine artery embolization in the treatment of uterine leiomyoma has been rarely associated with dislodgement and expulsion of infarcted uterine fibroids through the vagina, peritoneum, or bowel wall, predomi...

    Authors: Jeffrey L. Roberson, Lauren N. Krumeich, Nabil F. Darwich, Victor Babatunde, Dorottya Laczko, Andrew Albee, Zhaohai Yang, Amr El Jack, Richard Shlansky-Goldberg, Mary DeAgostino-Kelly and Benjamin M. Braslow

    Citation: Journal of Medical Case Reports 2021 15:356

    Content type: Case report

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  34. Paraganglioma is a very rare cause of pregnancy-induced hypertension. The objective of this case report is to present a case of paraganglioma presented during pregnancy and missed. Later, the diagnosis was mad...

    Authors: Ramjan Sanas Mohamed, Charles Naveenan Antonypillai and Harishanthi Mahendran

    Citation: Journal of Medical Case Reports 2021 15:352

    Content type: Case report

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  35. Pulmonary alveolar proteinosis is a rare interstitial lung disease characterized by accumulating surfactant materials in the alveoli. The autoimmune form is by far the most common in adults, while in the pedia...

    Authors: Abdalla Mohmed Alasiri, Reem Abdullah Alasbali, Meaad Ali Alaqil, Aishah Marei Alahmari, Nouf Dagash Alshamrani and Rabab Nasir Badri

    Citation: Journal of Medical Case Reports 2021 15:340

    Content type: Case report

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  36. Hemophagocytic lymphohistiocytosis is a rare, potentially fatal syndrome of immune hyperactivation. Here we describe a ganglionar tuberculosis evolving to hemophagocytic lymphohistiocytosis following adjuvant ...

    Authors: Cesar M. Costa, Luiza L. Gadotti, Maria C. Seiwald, Alessandra C. R. Salgues, Fernando Ganem, Ellen C. T. Nascimento, David E. Uip, Celso Arrais-Rodrigues and Rodrigo R. Munhoz

    Citation: Journal of Medical Case Reports 2021 15:350

    Content type: Case report

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  37. Rituximab is a novel chimeric monoclonal antibody that has established itself as a potent therapeutic option for autoimmune medical conditions, including systemic lupus erythematosus, owing to its mechanism of...

    Authors: Jevon Yudhishdran, Jeyalakshmy Sivakumar, Mitrakrishnan Rayno Navinan and Sareesh Bandapatti

    Citation: Journal of Medical Case Reports 2021 15:339

    Content type: Case report

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  38. Ovarian hyperstimulation syndrome is usually an iatrogenic and potentially life-threatening disease. It develops following ovulation induction and use of in vitro fertilization techniques.

    Authors: Abraham Fessehaye and Wondimu Gudu

    Citation: Journal of Medical Case Reports 2021 15:338

    Content type: Case report

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  39. Nivolumab, an anti-programmed cell death protein 1 antibody, is commonly used as an immune checkpoint inhibitor in various cancers. Various adverse events are associated with these therapies, including hepatit...

    Authors: Feifei Wang, Yang Liu, Wei Xu, Changjing Zhang, Jianhong Lv and Shaolin Ma

    Citation: Journal of Medical Case Reports 2021 15:336

    Content type: Case report

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  40. Rhabdomyomas comprise the majority of cardiac tumors in fetuses and are found in association with tuberous sclerosis complex. More than 90% of fetuses and neonates with multiple cardiac rhabdomyomas have signs...

    Authors: Koji Yamamoto, Yohei Maki, Yuichiro Sato, Hiroyuki Tanaka, Tsuyoshi Fukushima, Junko Ushijima, Seishi Furukawa, Hiroshi Sameshima and Hiroaki Kataoka

    Citation: Journal of Medical Case Reports 2021 15:334

    Content type: Case report

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  41. Adrenal incidentalomas are often found during investigation for another tumor or unrelated problems. Except for adrenal myelolipoma (second most common primary adrenal incidentaloma following adrenocortical ad...

    Authors: Mohammad Hossein Anbardar, Neda Soleimani, Saman Nikeghbalian and Maryam Mohebbi

    Citation: Journal of Medical Case Reports 2021 15:333

    Content type: Case report

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  42. Immunotherapy has become an efficacious option in the management of solid organ malignancies. Immune-related adverse events including pneumonitis are well described and may be particularly of concern in patien...

    Authors: Sarah Picard, Desiree Goh, Ashley Tan, Nisha Sikotra, Eli Gabbay and Tim Clay

    Citation: Journal of Medical Case Reports 2021 15:332

    Content type: Case report

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  43. Hemobilia is a rare cause of upper gastrointestinal bleeding that originates from the biliary tract. It is infrequently considered in diagnosis, especially in the absence of abdominal trauma or history of hepa...

    Authors: Kurniawan Kurniawan, I Dewa Nyoman Wibawa, Gde Somayana, I Ketut Mariadi and I Made Mulyawan

    Citation: Journal of Medical Case Reports 2021 15:331

    Content type: Case report

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  44. Chronic facial pain is a serious condition affecting millions of people worldwide. The reasons for chronic facial pain vary, and currently, the methods of treating chronic facial pain are expensive, invasive, ...

    Authors: Jintakorn Kuvatanasuchati and Karoon Leowsrisook

    Citation: Journal of Medical Case Reports 2021 15:337

    Content type: Case report

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  45. Epithelioid sarcoma most frequently occurs in the dermal or subcutaneous area of the distal extremities. To date, there have been three cases of primary pulmonary epithelioid sarcoma reported. We report a case...

    Authors: Eiki Mizutani, Riichiro Morita, Keiko Abe, Makoto Kodama, Shogo Kasai, Yasumi Okochi and Noriko Motoi

    Citation: Journal of Medical Case Reports 2021 15:330

    Content type: Case report

    Published on:

  46. Pancreatic transplantation is a definitive treatment for selected patients with insulin-dependent diabetes. It is a technically challenging surgery, and vascular complications are the most common cause of panc...

    Authors: Túlio Fabiano de Oliveira Leite, Lucas Vatanabe Pazinato, Thiago Franchi Nunes and Joaquim Mauricio da Motta Leal Filho

    Citation: Journal of Medical Case Reports 2021 15:329

    Content type: Case report

    Published on:

  47. Spontaneous subdural hematoma rarely presents with a hypervascular or malignant tumor but even less frequently in a benign tumor like meningioma. We encountered a patient with acute subdural hematoma associate...

    Authors: Ji Won Nam, Eun Suk Park, Jun Bum Park, Jae Hee Seo, Minsoo Kim and Na Young Jung

    Citation: Journal of Medical Case Reports 2021 15:335

    Content type: Case report

    Published on:

  48. Systemic lupus erythematosus is a rare autoimmune disorder, with the prevalence in Asia ranging from 30 to 50/100,000. The diagnosis of systemic lupus erythematosus is made according to the 2019 European Leagu...

    Authors: K. P. Jayawickreme, S. Subasinghe, S. Weerasinghe, L. Perera and P. Dissanayaka

    Citation: Journal of Medical Case Reports 2021 15:328

    Content type: Case report

    Published on:

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