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  1. Subdiaphragmatic abscesses are sometimes caused by intraabdominal infections. We report a case of endoscopic ultrasound-guided transgastric drainage.

    Authors: Tomoya Takami, Hiroshi Takihara, Koji Yasuda, Nozomi Kasyu, Hiroyuki Yoshitake, Hiroshi Shintani, Naoki Kataoka, Tomoyuki Yamaguchi and Shinichiro Makimoto
    Citation: Journal of Medical Case Reports 2021 15:396
  2. Serotonin toxicity is a known side effect of selective serotonin reuptake inhibitors and has previously also been described as a possible side effect of 5-hydroxytryptamine receptor agonist (triptan) medicatio...

    Authors: Gilbert Jin and Philip Stokes
    Citation: Journal of Medical Case Reports 2021 15:371
  3. Chronic myelomonocytic leukemia is a myelodysplastic/myeloproliferative neoplasm characterized by the infiltration of blood and bone marrow by immature monocytes. Cerebral localization of chronic myelomonocyti...

    Authors: Clémence Haméon, Cécilia Rousselot, Flavie Arbion, Justine Cibron, Jean-Philippe Cottier, Christophe Destrieux, Olivier Hérault and Emmanuel Gyan
    Citation: Journal of Medical Case Reports 2021 15:368
  4. Perivascular epithelioid cell tumors are defined by the World Health Organization as “a collection of rare mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epith...

    Authors: Ali McBride, Andrew J. Garcia, Lauren J. Sanders, Kelly Yiu, Lee D. Cranmer, Phillip H. Kuo, Matthew Kay and Andrew S. Kraft
    Citation: Journal of Medical Case Reports 2021 15:400
  5. Proton pump inhibitors are frequently used (and often overused) medications with adverse effects including vitamin B12 deficiency, Clostridium difficile colitis, and increased risk of chronic kidney disease. Erec...

    Authors: Theodore W. Perry
    Citation: Journal of Medical Case Reports 2021 15:360
  6. When diagnosing and treating neck masses, various diseases need to be considered, including benign or malignant tumors, lymph node-related diseases, and cysts. Thus, there may be cases in which making a defini...

    Authors: Hiroyuki Kaneko, Mami Deguchi and Hisashi Yano
    Citation: Journal of Medical Case Reports 2021 15:402
  7. Leptospirosis is an underdiagnosed bacterial infection with nonspecific symptoms, hence, a diagnostic challenge. Identifying a case of leptospirosis in Switzerland is uncommon. Although kidney complications ar...

    Authors: Marc Weiner, Matteo Coen, Jacques Serratrice, Thomas A. Mavrakanas and Antonio Leidi
    Citation: Journal of Medical Case Reports 2021 15:358

    The Correction to this article has been published in Journal of Medical Case Reports 2021 15:434

  8. Syndrome of inappropriate antidiuretic hormone secretion can be caused by arginine-vasopressin-producing tumors or enhanced arginine vasopressin secretion from the posterior pituitary gland due to central nerv...

    Authors: Masanori Hasebe, Jun Shirakawa, Daisuke Miyashita, Rieko Kunishita, Mayu Kyohara, Tomoko Okuyama, Yu Togashi and Yasuo Terauchi
    Citation: Journal of Medical Case Reports 2021 15:390
  9. Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neopla...

    Authors: Marah Hamdan, Jesse C. Qiao and Vid Fikfak
    Citation: Journal of Medical Case Reports 2021 15:357
  10. Cystoid macular edema is a rare, vision-threatening side effect of the taxane family of anticancer agents. There is no established treatment or standard treatment protocol for taxane-related cystoid macular ed...

    Authors: Mitsuru Otsubo, Reiko Kinouchi, Takayuki Kamiya and Akitoshi Yoshida
    Citation: Journal of Medical Case Reports 2021 15:355
  11. The clinical history and outcomes of coronavirus disease 2019 among people not hospitalized is not yet well characterized. To better inform clinical evaluation, we set out to characterize the natural history o...

    Authors: Stefania Dzieciolowska, Oumeet Ravi and Roland Grad
    Citation: Journal of Medical Case Reports 2021 15:393
  12. The topic of natural immunity related to severe acute respiratory syndrome coronavirus 2 remains controversial. Although evidence suggests postinfection immunity can be achieved, there have been reported cases...

    Authors: Nimrah Bader, Mahmood Khattab and Fahmi Farah
    Citation: Journal of Medical Case Reports 2021 15:392
  13. Hyperammonemic encephalopathy, a rare but fatal condition, is increasingly being reported as a possible complication of bariatric surgery. Here, we present a case of hyperammonemic encephalopathy, focusing on ...

    Authors: Nuphar Vinegrad, Orna Staretz-Chacham, Leonid Barski and Carmi Bartal
    Citation: Journal of Medical Case Reports 2021 15:385
  14. Clinical guidelines do not recommend further investigation for occult malignancy in the scenario of unprovoked venous thromboembolism in the absence of additional clinical features suggestive of malignancy. We...

    Authors: Kaitlin J. Mayne, Emma Lewis and Lewis Vickers
    Citation: Journal of Medical Case Reports 2021 15:354
  15. Morel-Lavallée lesions are posttraumatic, closed degloving injuries in which the skin and subcutaneous tissue are separated abruptly from superficial underlying fascia. This condition leads to an effusion cont...

    Authors: Claude Kasereka Masumbuko, Gabriel Kambale Bunduki and Mupenzi Mumbere
    Citation: Journal of Medical Case Reports 2021 15:383
  16. Hodgkin’s Lymphoma (HL) is a rare malignancy characterised histologically by the presence of Reed-Sternberg cells. Diagnosis of lymphomas can be difficult due to broad, non-specific presentations of disease, w...

    Authors: Anamika Banerjee, Kaljit Bhuller, Rajini Sudhir and Amrita Bajaj
    Citation: Journal of Medical Case Reports 2021 15:351
  17. Phlebosclerotic colitis is a rare condition with a high mortality. It has been seen almost exclusively in Asian patients who are ≥ 60 years old, with a slight male predominance. Although it predominantly affec...

    Authors: J. Mohigefer, P. Gómez-Millán and J. J. Borrero
    Citation: Journal of Medical Case Reports 2021 15:349
  18. Glomangioma is a benign tumor of mesenchymal origin, derived from the glomus body. It is responsible for the thermal regulation of the dermis. The occurrence of oncogenic osteomalacia related to glomangioma is...

    Authors: Camila R. Muniz, Gabriela A. M. Bezerra, Viviane C. da Silva, Priscilla M. F. Aguiar, Gunter Gerson, Catarina B. D’Alva and André A. A. Nunes
    Citation: Journal of Medical Case Reports 2021 15:348
  19. Coronavirus disease 2019 has been a public health threat and a worldwide emergency for more than a year. Unfortunately, many questions concerning the pathophysiology, management, and long-term side effects rem...

    Authors: Hussein Awada, Hasan Nassereldine and Adel Hajj Ali
    Citation: Journal of Medical Case Reports 2021 15:382
  20. The novel coronavirus, since its first identification in China, in December 2019, has shown remarkable heterogeneity in its clinical behavior. It has affected humans on every continent. Clinically, it has affe...

    Authors: Ahmed Maseh Haidary, Sarah Noor, Esmatullah Hamed, Tawab Baryali, Soma Rahmani, Maryam Ahmad, Farahnaz Erfani, Hashmatullah Azimi, Habib Ul Rahman Habib, Gul Ahmad Tahiri, Ramin Saadaat, Abdul Sami Ibrahimkhil, Esmatullah Esmat and Haider Ali Malakzai
    Citation: Journal of Medical Case Reports 2021 15:379
  21. Solitary pulmonary nodules are the most common incidental finding on chest imaging. Their management is very well defined by several guidelines, with risk calculators for lung cancer being the gold standard. S...

    Authors: George Tsaknis, Muhammad Naeem, Advitya Singh and Siddharth Vijayakumar
    Citation: Journal of Medical Case Reports 2021 15:347
  22. Atopic dermatitis is a chronic inflammatory skin disease associated with pruritus. Skin affected by atopic dermatitis not only shows a high percentage of Staphylococcus aureus colonization, but corneal barrier dy...

    Authors: Shuhei Kubota, Masaaki Nemoto, Yuki Sakaeyama, Chie Nakada, Masataka Mikai, Yutaka Fuchinoue, Kosuke Kondo, Naoyuki Harada and Nobuo Sugo
    Citation: Journal of Medical Case Reports 2021 15:373
  23. Klüver–Bucy syndrome is a rare and complex neurobehavioral cluster that occurs in humans and results from a temporal lobe lesion. It can be associated with a variety of causes. Stroke is a rarely reported caus...

    Authors: Alawi Aqel Al-Attas, Abdulrahman Yousef Aldayel, Tareq Hamad Aloufi and Nabil Biary
    Citation: Journal of Medical Case Reports 2021 15:346
  24. We present an unusual case of a patient who developed four melanomas within a few months of diagnosis with human immunodeficiency virus and commencement of highly active antiretroviral therapy therapy. The pat...

    Authors: Sharad P. Paul, Simon Briggs and Michael Hitchcock
    Citation: Journal of Medical Case Reports 2021 15:367
  25. Primary malignant melanoma of the esophagus is a rare form of mucosal melanoma with a poor prognosis. While immune checkpoint inhibitors have recently extended overall survival in metastatic melanoma, data on ...

    Authors: Takeshi Okamoto, Eriko Nakano and Teruo Yamauchi
    Citation: Journal of Medical Case Reports 2021 15:345
  26. Cavities are frequent manifestations of a wide variety of pathological processes involving the lung. There has been a growing body of evidence of coronavirus disease 2019 leading to a cavitary pulmonary disease.

    Authors: Goar Egoryan, Elise Hyser, Ammar H. Mushtaq, Maria Adriana Yanez-Bello, Daniela Patricia Trelles-Garcia, Harvey J. Friedman and Guillermo Rodriguez-Nava
    Citation: Journal of Medical Case Reports 2021 15:377
  27. Diaphragmatic hernia involves protrusion of abdominal contents into the thorax through a defect in the diaphragm. This defect can be caused either by developmental failure of the posterolateral foramina to fus...

    Authors: Konstantinos G. Spiridakis, Mathaios E. Flamourakis, Ioannis G. Gkionis, Eleni I. Kaloeidi, Anthoula I. Fachouridi, Styliani E. Konstantoulaki, Eleni S. Tsagkataki, Michail I. Giakoumakis, Emmamouil A. Vassilogiannakis, Georgios E. Kostakis and Manousos S. Christodoulakis
    Citation: Journal of Medical Case Reports 2021 15:372
  28. Encapsulating peritoneal sclerosis is a rare but potentially lethal complication of long-term peritoneal dialysis that is associated with significant morbidity and mortality. The occurrence of encapsulating pe...

    Authors: Saeed Mohammed AlZabali, Abdulkarim AlAnazi, Khawla A. Rahim and Hassan Y. Faqeehi
    Citation: Journal of Medical Case Reports 2021 15:366
  29. Bordetella trematum is unknown to most clinicians and microbiologists. However, this Gram-negative opportunistic bacterium can be responsible for ulcer superinfection but also bacteremia and sometimes death by se...

    Authors: M. Lacasse, K. Inyambo, A. Lemaignen, M. Mennecart, S. Gensburger, A. S. Valentin, L. Bernard and B. Fougère
    Citation: Journal of Medical Case Reports 2021 15:365
  30. Fibroids of the uterus are the most common benign pelvic tumors in women worldwide. Their diagnosis is usually not missed because of the widespread and well-established use of ultrasound in gynecological clini...

    Authors: Wiesener Viva, Dhanawat Juhi, Andresen Kristin, Mathiak Micaela, Both Marcus, Alkatout Ibrahim and Bauerschlag Dirk
    Citation: Journal of Medical Case Reports 2021 15:344
  31. The presence of isolated metachronous adrenal metastasis in patients with esophageal cancer is rare. There is significant controversy regarding the management of such patients. Adrenal metastasectomy has been ...

    Authors: Tarun Jindal, Ankush Sarwal, Pravin Pawar, M. Dhanalakshmi and Neeraj Subedi
    Citation: Journal of Medical Case Reports 2021 15:369
  32. The new coronavirus disease 2019 pandemic has spread throughout most of the world. Cerebral venous thrombosis is a rare thromboembolic disease that can present as an extrapulmonary complication in coronavirus ...

    Authors: Henry Robayo-Amortegui, Natalia Valenzuela-Faccini, Cesar Quecano-Rosas, Darlyng Zabala-Muñoz and Michel Perez-Garzon
    Citation: Journal of Medical Case Reports 2021 15:364
  33. Recurrent coronavirus disease 2019 (COVID-19) infection is an emerging problem and may prove to be one of the greatest problems in controlling the pandemic in the future. Recurrent infections can be due to rea...

    Authors: Jaya Garg, Jyotsna Agarwal, Anupam Das and Manodeep Sen
    Citation: Journal of Medical Case Reports 2021 15:363
  34. Disorders of sex development are anomalies in which the development of urogenital ridge is undifferentiated for the male and female child. Imaging plays a vital role in investigating the gross anatomy and asso...

    Authors: Mahamudu Ayamba Ali, Raymond Saa-Eru Maalman, Yaw Otchere Donkor and James Edward Mensah
    Citation: Journal of Medical Case Reports 2021 15:362
  35. The surgical management of esophageal atresia in extreme-low-birth-weight infants (< 1000 g) is challenging. We report on an extreme-low-birth-weight infant who was extremely preterm (510 g, 25 + 5 weeks) and ...

    Authors: Xiaoyan Feng, Ulrich Thomé, Holger Stepan, Martin Lacher and Richard Wagner
    Citation: Journal of Medical Case Reports 2021 15:361
  36. Aneurysm formation is a possible, but rare, complication of granulomatosis with polyangiitis, known as Wegener’s granulomatosis. Urgent diagnosis and therapy is very important because a ruptured aneurysm could...

    Authors: A. Gravos, K. Katsifa, P. Tselioti, V. Grammatikopoulou, K. Sakellaridis, S. Kanakaki, C. Tsapas, A. Destounis, H. Moschouris, I. Athanasiadou, F. Chatzivasiloglou, E. Ivanova and A. Prekates
    Citation: Journal of Medical Case Reports 2021 15:343
  37. Pleural effusion and pleuritis are uncommon manifestations of Mycobacterium avium complex pulmonary disease. Pleuritis caused by Mycobacterium avium complex pulmonary disease presenting as a solitary pulmonary no...

    Authors: Shigenari Nukaga, Hiroaki Murakami, Kazuma Yagi, Ryosuke Satomi, Takahiko Oyama, Arafumi Maeshima and Yoshitaka Oyamada
    Citation: Journal of Medical Case Reports 2021 15:342
  38. Superficial siderosis is a rare disease involving hemosiderin deposits on the surface of brain or spinal cord that are thought to cause clinical symptoms, which usually consist of cranial nerve dysfunction, ce...

    Authors: Tobias Braun, Maxime Viard, Tobias Struffert, Omar AlhajOmar, Mesut Yeniguen and Martin Juenemann
    Citation: Journal of Medical Case Reports 2021 15:353
  39. Since its debut recognition in 1981, human immunodeficiency virus/acquired immunodeficiency syndrome has affected over 77 million people and has resulted in premature cessation of 35.4 million lives worldwide....

    Authors: Pedro Pallangyo, Jalack Millinga, Happy Swai, Naairah R. Hemed, Zabela Mkojera, Silvia Mosha, Marcelina Granima, Smita Bhalia, Yona Gandye and Mohamed Janabi
    Citation: Journal of Medical Case Reports 2021 15:341
  40. We diagnosed a clinical case of pulmonary infection involving Mycobacterium tuberculosis and Tropheryma whipplei in a patient with acute respiratory distress syndrome. The diagnosis was assisted by metagenomic ne...

    Authors: Binghua Zhu, Jing Tang, Rong Fang, Xuejie Fei, Qing Wang, Wenqing Wang, Xueqin Wu, Chao Liu and Qian Wang
    Citation: Journal of Medical Case Reports 2021 15:359
  41. Uterine artery embolization in the treatment of uterine leiomyoma has been rarely associated with dislodgement and expulsion of infarcted uterine fibroids through the vagina, peritoneum, or bowel wall, predomi...

    Authors: Jeffrey L. Roberson, Lauren N. Krumeich, Nabil F. Darwich, Victor Babatunde, Dorottya Laczko, Andrew Albee, Zhaohai Yang, Amr El Jack, Richard Shlansky-Goldberg, Mary DeAgostino-Kelly and Benjamin M. Braslow
    Citation: Journal of Medical Case Reports 2021 15:356
  42. Paraganglioma is a very rare cause of pregnancy-induced hypertension. The objective of this case report is to present a case of paraganglioma presented during pregnancy and missed. Later, the diagnosis was mad...

    Authors: Ramjan Sanas Mohamed, Charles Naveenan Antonypillai and Harishanthi Mahendran
    Citation: Journal of Medical Case Reports 2021 15:352
  43. Pulmonary alveolar proteinosis is a rare interstitial lung disease characterized by accumulating surfactant materials in the alveoli. The autoimmune form is by far the most common in adults, while in the pedia...

    Authors: Abdalla Mohmed Alasiri, Reem Abdullah Alasbali, Meaad Ali Alaqil, Aishah Marei Alahmari, Nouf Dagash Alshamrani and Rabab Nasir Badri
    Citation: Journal of Medical Case Reports 2021 15:340
  44. Hemophagocytic lymphohistiocytosis is a rare, potentially fatal syndrome of immune hyperactivation. Here we describe a ganglionar tuberculosis evolving to hemophagocytic lymphohistiocytosis following adjuvant ...

    Authors: Cesar M. Costa, Luiza L. Gadotti, Maria C. Seiwald, Alessandra C. R. Salgues, Fernando Ganem, Ellen C. T. Nascimento, David E. Uip, Celso Arrais-Rodrigues and Rodrigo R. Munhoz
    Citation: Journal of Medical Case Reports 2021 15:350
  45. Rituximab is a novel chimeric monoclonal antibody that has established itself as a potent therapeutic option for autoimmune medical conditions, including systemic lupus erythematosus, owing to its mechanism of...

    Authors: Jevon Yudhishdran, Jeyalakshmy Sivakumar, Mitrakrishnan Rayno Navinan and Sareesh Bandapatti
    Citation: Journal of Medical Case Reports 2021 15:339
  46. Ovarian hyperstimulation syndrome is usually an iatrogenic and potentially life-threatening disease. It develops following ovulation induction and use of in vitro fertilization techniques.

    Authors: Abraham Fessehaye and Wondimu Gudu
    Citation: Journal of Medical Case Reports 2021 15:338
  47. Nivolumab, an anti-programmed cell death protein 1 antibody, is commonly used as an immune checkpoint inhibitor in various cancers. Various adverse events are associated with these therapies, including hepatit...

    Authors: Feifei Wang, Yang Liu, Wei Xu, Changjing Zhang, Jianhong Lv and Shaolin Ma
    Citation: Journal of Medical Case Reports 2021 15:336

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