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Fig. 1 | Journal of Medical Case Reports

Fig. 1

From: Laryngeal polyp associated with reflux disease: a case report

Fig. 1

Histopathological features of laryngeal polyp. a The polyp is lined with thickened, nonkeratinized, stratified squamous epithelial covering with disruption of superficial layers of epithelium causing intraepidermal microabscesses (black arrows). The underlying stroma shows edema (arrowhead) and hemorrhage (red arrow) (Hematoxylin and eosin stain (H&E) stain, original magnification × 100). b Focal elongation of rete ridges is present with mild atypical epithelial cell changes (black arrows) (Hematoxylin and eosin stain (H&E) stain, original magnification × 200). c The underlying stroma shows numerous proliferated blood vessels (red arrows); some are congested. Two nests of uniform squamous epithelium are present with intracellular keratinization and surrounded with basement membrane, representing uniform foci of pseudoepitheliomatous hyperplasia (black arrows) (Hematoxylin and eosin stain (H&E) stain, original magnification × 40). d The stroma shows dense fibrous tissue deposition (black arrow) with numerous focal accumulations of foamy macrophages (red arrow). Focal separation of the overlying epithelial covering with edema is present (arrowhead) (Hematoxylin and eosin stain (H&E) stain, original magnification × 200)

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