Fig. 3
From: Chordoma dedifferentiation after proton beam therapy: a case report and review of the literature
![Fig. 3](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13256-016-1076-3/MediaObjects/13256_2016_1076_Fig3_HTML.gif)
Hematoxylin and eosin stain showing pathognomonic physaliphorous cells with multivacuolated cytoplasm (arrows), mixed with epithelioid cells. Nuclei are relatively bland without significant pleomorphism. Magnification 40×