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Replantation of a displaced incisor in a boy with a cleft lip and alveolus: a case report
© The Author(s). 2016
Received: 11 April 2016
Accepted: 25 August 2016
Published: 15 September 2016
Tooth replantation after traumatic avulsion or transplantation is a challenge in oral surgery. A special method named auto-alloplastic replantation, in which a titanium post is used after extraoral endodontic treatment, combines several advantages. The treatment is performed in one step with no further endodontic intervention, no wide root canal instrumentation, no recontamination, and reduced endodontic infection. This is the first report on replantation of an ectopic tooth in a patient with a cleft lip and alveolus using this method.
This case report presents the treatment of a 13-year-old white boy with a cleft lip and alveolus who had an ectopic incisor in the cleft region. His rehabilitation was performed by a tooth transposition using the auto-alloplastic replantation technique. After preparation of the displaced incisor from the vestibule, extraoral endodontic treatment followed using a titanium post prior to replantation in a newly formed socket. In the follow-up, the tooth is still in place and functioning after 2 years.
This method can be used to bridge the years while a patient is young and jaw growth is incomplete until bone augmentation and implantation can be performed. The tooth will preserve the remaining alveolar ridge and help the adolescent psychologically.
Ectopic development of teeth is known in patients with a cleft lip and alveolus for various reasons. Teeth can appear in different locations in the mouth, the nose, and the sinus. Rare abnormal positions have been reported in the nose [1, 2] or in the maxillary sinus . These teeth cannot be preserved and must be removed.
Cases with tooth transplantation in patients with a cleft lip and alveolus are rare, but a case has been reported on a secondary bone graft with simultaneous auto-tooth transplantation . The positive effect of a tooth in the alveolar ridge is to stabilize the maxillary arch. Furthermore, dental roots support the growing maxilla and the transplantation of a tooth prevents reabsorption of the bone. In a case series about the indications for the use of autotransplantation of teeth, one case describes a successful transplantation of the left permanent canine into the position of the dilacerated maxillary left permanent central incisor region . Another successful autotransplantation of a premolar to the incisor region in a patient with a cleft lip and alveolus is described 6 months after bone grafting the defect in the cleft area . Furthermore, a systematic review and meta-analysis on tooth autotransplantation found an excellent survival rate that ranged from 75.3 to 91 % . In a study, 215 patients were examined after autotransplantation with a median follow-up of 4.8 years and showed a success rate of 81 %; the highest success rate was in the maxillary incisor region with 100 % . Specific knowledge concerning the frontal region was presented for the autotransplantation of premolars to the maxillary incisor region after follow-up of 12 to 22 years .
Tooth replantation can be considered an effective alternative to dental implant, when the latter is contraindicated in a young patient with incomplete skeletal development  or in special cases with dentigerous cyst . In dental traumatology, there is a special method for the treatment of avulsed or severely traumatized incisors: auto-alloplastic replantation. Auto-alloplastic replantation of a tooth describes transplantation with vital periodontal ligament and an alloplastic retrograde titanium post after extraoral endodontic treatment and antireabsorptive-regenerative therapy [12, 13]. The indication for this treatment protocol includes the replantation of avulsed teeth or transplantation of primary canines . For later prosthetic rehabilitation of a missing tooth in patients with a cleft lip and alveolus, dental implants are a feasible solution [15, 16]. Implants can replace a single tooth, mostly the lateral incisor in the cleft area, or can support a dental prosthesis if more than one tooth is missing.
Due to the fact that there are only a handful of publications about auto-replantation of a tooth in patients with a cleft lip and alveolus, it is necessary to communicate these alternative treatment methods and their outcome.
The psychological aspect of this condition should not be underestimated because he was ashamed of his front teeth and was not able to smile. He describes the appearance of his maxillary anterior teeth as unaesthetic. In cooperation with the Department of orthodontics, a decision for surgical intervention was made.
The guidelines of the International Association of Dental Traumatology (IADT) for the success or failure of replantation describe the success criteria as clinically asymptomatic, normal mobility, no apical lesion in a radiograph, and no reabsorption or ankylosis of the root . The presented case fits all the criteria; however, the mobility could not be tested due to orthodontic treatment.
One case report suggested secondary bone grafting with simultaneous auto-tooth transplantation as an option for alveolar cleft treatment . In a larger case series, seven cases were presented that demonstrated the versatility of autotransplantation in a range of clinical situations. The authors noted that autotransplantation provides an excellent outcome in a growing child, with the advantage that it is a biologically compatible method of tooth replacement that promotes pulp and periodontal healing and enables orthodontic movement if necessary . An interesting example of the transplantation of a canine to an incisor region with endodontic therapy and composite reshaping showed a successful follow-up over 2 years . All these descriptions of treatment plans have one goal: to support the bone of the maxillary arch for the continuity of dental alignment. The maintenance of permanent teeth in the dental arch restores occlusal function, which contributes to the improvement of alveolar development in a growing patient . The presented case has the same aim: to form a dental arch and preserve hard and soft tissues. We can recommend autotransplantation of incisors in patients with a cleft lip and alveolus to bridge the time until bone grafting or dental implantation becomes a viable option.
Although these cases are rare, some publications report on the replantation of teeth in patients with a cleft lip and alveolus. Every case with a combination of cleft, tooth dislocation, or agenesis and compromised bone in the alveolar ridge presents a unique situation. Therefore, these cases require our special attention and an individual treatment plan. More publications offering a whole variety of treatment options are necessary in order for us to benefit from these unusual experiences.
The authors thank Dr Andreas May for providing the special surgical kit for transplantation.
This manuscript was not supported by any funding.
Availability of data and materials
The raw data are available from email@example.com.
HS planned the case and treated the patient. HK carried out the operation. FP is responsible for the clinical follow-up, photography, and radiography. NB carried out the orthodontic treatment. SA is responsible for the treatment method design. All authors read and approved the final manuscript.
The authors declare that they have no competing interests.
Consent for publication
Written informed consent was obtained from the patient’s legal guardians for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
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- Yeung KH, Lee KH. Intranasal tooth in a patient with a cleft lip and alveolus. Cleft Palate Craniofac J. 1996;33(2):157–9.View ArticlePubMedGoogle Scholar
- Gupta YK, Shah N. Intranasal tooth as a complication of cleft lip and alveolus in a four year old child: case report and literature review. Int J Paediatr Dent. 2001;11(3):221–4.View ArticlePubMedGoogle Scholar
- Viterbo S, Griffa A, Boffano P. Endoscopic removal of an ectopic tooth in maxillary sinus. J Craniofac Surg. 2013;24(1):e46–8.View ArticlePubMedGoogle Scholar
- Miura K, Yoshida M, Asahina I. Secondary bone grafting with simultaneous auto-tooth transplantation to the alveolar cleft. J Oral Maxillofac Surg. 2015;73(6):1050–7.View ArticlePubMedGoogle Scholar
- Waldon K, et al. Indications for the use of auto-transplantation of teeth in the child and adolescent. Eur Arch Paediatr Dent. 2012;13(4):210–6.View ArticlePubMedGoogle Scholar
- Luvizuto ER, et al. Bone augmentation and autogenous transplantation of premolar to the site of the fissure in a cleft palate patient. Dent Traumatol. 2013;29(6):483–8.View ArticlePubMedGoogle Scholar
- Machado LA, et al. Long-term prognosis of tooth autotransplantation: a systematic review and meta-analysis. Int J Oral Maxillofac Surg. 2016;45(5):610–7.View ArticlePubMedGoogle Scholar
- Kvint S, et al. Autotransplantation of teeth in 215 patients. A follow-up study. Angle Orthod. 2010;80(3):446–51.View ArticlePubMedGoogle Scholar
- Stange KM, Lindsten R, Bjerklin K. Autotransplantation of premolars to the maxillary incisor region: a long-term follow-up of 12-22 years. Eur J Orthod. 2015. doi: 10.1093/ejo/cjv078.
- Ferrazzano GF, et al. Tooth replantation as an alternative to dental implantology in adolescent patients. Eur J Paediatr Dent. 2010;11(4):216–8.PubMedGoogle Scholar
- Picciotti M, et al. Replantation of tooth involved in dentigerous cyst: a case report. Eur J Paediatr Dent. 2012;13(4):349–51.PubMedGoogle Scholar
- Pohl Y, Filippi A, Kirschner H. Extraoral endodontic treatment by retrograde insertion of posts: a long-term study on replanted and transplanted teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95(3):355–63.View ArticlePubMedGoogle Scholar
- Pohl Y, Filippi A, Kirschner H. Results after replantation of avulsed permanent teeth. I. Endodontic considerations. Dent Traumatol. 2005;21(2):80–92.View ArticlePubMedGoogle Scholar
- Pohl Y, Geist P, Filippi A. Transplantation of primary canines after loss or ankylosis of upper permanent incisors. A prospective case series study on healing and survival. Dent Traumatol. 2008;24(4):388–403.View ArticlePubMedGoogle Scholar
- de Barros Ferreira Jr S, et al. Survival of dental implants in the cleft area – a retrospective study. Cleft Palate Craniofac J. 2010;47(6):586–90.View ArticleGoogle Scholar
- Filho JF, de Almeida AL. Aesthetic analysis of an implant-supported denture at the cleft area. Cleft Palate Craniofac J. 2013;50(5):597–602.View ArticlePubMedGoogle Scholar
- Kirschner H, et al. Eine neue Methode kombinierter auto-alloplastischer Zahnreplantation mit partieller Al2-O3-Keramikwurzel. Dtsch Zahnarztl Z. 1978;33:594–8.PubMedGoogle Scholar
- Flores MT, et al. Guidelines for the evaluation and management of traumatic dental injuries. Dent Traumatol. 2001;17(5):193–8.View ArticlePubMedGoogle Scholar