- Case report
- Open Access
Giant lipoma of the adrenal gland: a case report
© Patel et al; licensee BioMed Central Ltd. 2011
Received: 21 October 2009
Accepted: 24 February 2011
Published: 24 February 2011
Lipoma of the adrenal gland is rare with a reported incidence of between 2% to 4%. Improved imaging techniques have helped in the diagnosis of these lesions.
We report an incidentally detected giant adrenal lipoma in a 43-year-old Asian man with a six year history of hypertension. He had a myocardial infarction one year earlier, for which he was taking an antiplatelet agent in addition to antihypertensive medication.
The tumor was detected by computed tomography and magnetic resonance imaging, and was a large, well-defined, altered signal intensity lesion 12 cm in size in the right suprarenal region. The tumor was resected laparoscopically and sent for histopathologic evaluation. It measured 15 cm × 11.5 cm × 6.5 cm on gross examination, weighed 810 g and had a homogenous yellow cut surface. The postoperative course was smooth. Microscopy revealed mature adipose tissue with myxoid degeneration. Over the course of a four month follow-up the patient recovered.
Giant lipoma of the adrenal gland, a benign tumor, is rare compared with myelolipoma. Improved radiologic modalities have led to increased reporting of these benign tumors. Laparoscopic removal of the tumor has helped in early recovery and in reinstating patients to normal lives.
Lipomatous tumors of the adrenal gland are rare. Improved diagnostic modalities, including high-resolution ultrasonography, computed tomography (CT) and magnetic resonance imaging (MRI), have led to increased reporting and management of such tumors. We report one such case of an incidentally detected adrenal lipoma.
A 43-year-old Asian man was incidentally detected to have a loose, well-defined, homogenously enhancing soft tissue density lesion in the right adrenal gland. This lesion was found while the patient was undergoing investigations for hypertension of six years' duration being controlled with α- and β-blockers and a diuretic. The patient had a history of myocardial infarction nine earlier for which he underwent coronary angioplasty and he was taking an antiplatelet agent.
During this admission, he had undergone ultrasonography of the abdomen, which revealed an adrenal mass. No other significant history or findings were noted.
The patient had an uneventful postoperative course and is stable with the same medications continued for one month. The patient is now taking a beta-blocker and antiplatelet agents, and he has stopped taking the alpha-blocker and diuretic that he needed previously for blood pressure control.
Adrenal lipomas are benign tumors with a reported incidence of 2% to 4% of all adrenal tumors [1–4]. The differential diagnoses include myelolipoma, angiomyolipoma, liposarcoma and teratoma. The histogenesis of these mesenchymal tumors is still little understood. Lipomas are known to occur on the right side with male predominance as opposed to myelolipomas, which have no gender or site predilection. The size of these tumors is usually smaller than 4 cm; however, the term giant lipoma is preferred when the size exceeds 8 cm. Our patient had a tumor of more than 11 cm in diameter, thus falling in the category of "giant adrenal lipoma." No calcification was noted despite the lipoma's large size.
Giant adrenal lipomas are rare but are being reported more frequently because of improved modern imaging technologies. This tumor was removed with the rarely reported technique of transperitoneal laparoscopic adrenalectomy and was confirmed histologically.
Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
- Lam KY, Lo CY: Adrenal lipomatous tumors: a 30 year clinicopathological experience at a single institution. J Clin Pathol. 2001, 54 (9): 707-712.View ArticlePubMedPubMed CentralGoogle Scholar
- Milathianakis KN, Farfarelos CD, Mpogdanos IM, Karamanolakis DK: Giant lipoma of the adrenal gland. J Urol. 2002, 167 (4): 1777-10.1016/S0022-5347(05)65198-1.View ArticlePubMedGoogle Scholar
- Buettner A: Lipoma of the adrenal gland. Pathol Int. 1999, 49 (11): 1007-1009. 10.1046/j.1440-1827.1999.00966.x.View ArticleGoogle Scholar
- Reinig JW, Doppman JL, Dwyer AJ, Johnson AR, Knop RH: Adrenal masses differentiated by MR. Radiology. 1986, 158 (1): 81-4.View ArticlePubMedGoogle Scholar
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.