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Duodenal perforation due to a kink in a nasojejunal feeding tube in a patient with severe acute pancreatitis: a case report
© Tong et al; licensee BioMed Central Ltd. 2010
Received: 5 November 2009
Accepted: 28 May 2010
Published: 28 May 2010
Nasojejunal feeding tube placement can be achieved by fluoroscopic or endoscopic techniques. Significant complications due to nasojejunal feeding tube placement, such as hydrothorax, duodenal perforation and retroperitoneal emphysema, are very rare. We present a case of massive retroperitoneal emphysema and abscess because of duodenal perforation caused by a kink in a nasojejunal feeding tube.
A 34-year-old Chinese woman was admitted to our intensive care unit due to hypertriglyceridemia and severe acute pancreatitis. As she suffered from acute respiratory distress syndrome and required mechanical ventilation, a nasojejunal feeding tube was placed by transnasal endoscopic technique. The procedure took place at her bedside. Half a month later, she had a high fever and abdominal distension. An abdominal radiography was performed and showed that the nasojejunal feeding tube was kinking on the third portion of the duodenum and the tip of the nasojejunal feeding tube was inserted into the right retroperitoneum on the second portion of the duodenum.
When a nasojejunal feeding tube is placed through the transnasal endoscopic technique, an abdominal radiography should be used to confirm the tube's position and indicate if it is kinking or beyond the ligament of Treitz.
Enteral nutrition (EN) via a nasojejunal feeding tube (NJT) is a rational and acceptable method of nutritional support in patients with severe acute pancreatitis (SAP) [1–3]. NJT placement can be achieved through fluoroscopic or endoscopic techniques . Importantly, in patients with SAP, the NJT should be beyond the ligament of Treitz  and the NJT should not be kinked. Significant complications due to NJT, such as hydrothorax, duodenal perforation and retroperitoneal emphysema, are very rare [6, 7]. We report a case of massive retroperitoneal emphysema and an abscess caused by a duodenal perforation that resulted from a kink in a NJT.
In patients with SAP, EN via NJT beyond the ligament of Treitz has been shown to result in significantly fewer septic events and fewer overall complications [1, 2]. An NJT was placed on the fifth day after admission in order to provide EN to this patient. However, she suffered from ARDS and could not be transported to the radiology department. Thus, the NJT was placed at bedside using the transnasal endoscopic technique. However, abdominal radiography could not be used to demonstrate the position of the tube, whether it was kinking or beyond the ligament of Treitz.
Endoscopic NJT placement is a simple and effective method. We have experienced over a 96% success rate using this technique . However, pushing the NJT blindly beyond the second portion of the duodenum may result in a kink in the distal end, especially in patients with stenosis of the duodenum or swelling in the tail of the pancreas. Endoscopic related pneumoretroperitoneum due to duodenal perforation has been reported . But in this patient, we initially thought that the duodenal perforation was not a complication of endoscopic NJT placement because it was not until the 16th day after placement that she had a high fever and abdominal distension. The patient tolerated EN well for 15 days. The duodenum is the lack of serous membrane. When it is surrounded by peripancreatic inflammation and fluid, it becomes swollen and fragile. In this patient, the NJT was kinking on the third portion of the duodenum. Additionally, the tip of the NJT had collided with the wall of the duodenum on the second portion for a long time. Duodenal perforation may occur when the pressure of the tip is not removed in time. Once the tip of the NJT was inserted into the retroperitoneum and EN was not stopped, retroperitoneal emphysema and an abscess occurred immediately. When NJT is placed using endoscopic techniques, the final position must be determined by an abdominal radiography and interpreted by the attending radiologist.
The treatment for duodenal perforation is simple. The duodenum perforation may be cured spontaneously once the NJT is removed from the perforation, and the abscess is drained thoroughly. This is what happened with our patient.
When an NJT is placed at bedside by a transnasal endoscopic technique, the tube position should be demonstrated by abdominal radiography to determine whether there is kinking or if it is beyond the ligament of Treitz.
Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the journal's Editor-in-Chief.
- Olah A, Pardavi G, Belagyi T, Nagy A, Issekutz A, Mohamed GE: Early nasojejunal feeding in acute pancreatitis is associated with a lower complication rate. Nutrition. 2002, 18: 259-262. 10.1016/S0899-9007(01)00755-9.View ArticlePubMedGoogle Scholar
- Naked A, Piessevaux H, Marot JC, Hoang P, Geubel A, Van Steenbergen W, Reynaert M: Is early enteral nutrition in acute pancreatitis dangerous? About 20 patients fed by an endoscopically placed nasogastrojejunal tube. Pancreas. 1998, 172: 187-193. 10.1097/00006676-199808000-00013.View ArticleGoogle Scholar
- Meier R, Ockenga J, Pertkiewicz M, Pap A, Milinic N, Macfie J, Löser C, Keim V: ESPEN guidelines on enteral nutrition: pancreas. Clin Nutr. 2006, 25: 275-284. 10.1016/j.clnu.2006.01.019.View ArticlePubMedGoogle Scholar
- Zhihui T, Wenkui Y, Weiqin L, Zhiming W, Xianghong Y, Ning L, Jieshou L: A randomised clinical trial of transnasal endoscopy versus fluoroscopy for the placement of nasojejunal feeding tubes in patients with severe acute pancreatitis. Postgrad Med J. 2009, 85: 59-63. 10.1136/pgmj.2008.070326.View ArticlePubMedGoogle Scholar
- Vu MK, Veek Van Der P, Frolich M, Souverijn JH, Biemond I, Lamers CB, Masclee AA: Does jejunal feeding activate exocrine pancreatic secretion?. Eur J Clin Invest. 1999, 29: 1053-1059. 10.1046/j.1365-2362.1999.00576.x.View ArticlePubMedGoogle Scholar
- Yavaşcaoğlu B, Acar H, Işçimen R, Gurbet A, Uysal H, Kutlay O: Fatal hydrothorax due to misplacement of a nasoenteric feeding tube. J Int Med Res. 2001, 29: 437-40.View ArticlePubMedGoogle Scholar
- Chou TD, Ue ST, Lee CH, Lee TW, Chen TM, Wang HJ: Duodenal perforation as a complication of routine endoscopic nasoenteral feeding tube placement. Burns. 1999, 25: 86-87. 10.1016/S0305-4179(98)00143-0.View ArticlePubMedGoogle Scholar
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