Esophageal intramural pseudodiverticulosis characterized by barium esophagography: a case report
© O'Connor et al; licensee BioMed Central Ltd. 2010
Received: 3 December 2009
Accepted: 21 May 2010
Published: 21 May 2010
Esophageal intramural pseudodiverticulosis is a rare condition characterized by the dilatation of the submucosal glands.
We present a case of esophageal intramural pseudodiverticulosis in a 72-year-old Caucasian man who presented with dysphagia and with a background history of alcohol abuse. An upper gastrointestinal endoscopy of our patient showed an esophageal stricture with abnormal mucosal appearances, but no malignant cells were seen at biopsy. Appearances on a barium esophagram were pathognomonic for esophageal intramural pseudodiverticulosis.
We demonstrate the enduring usefulness of barium esophagography in the characterization of abnormal mucosal appearances at endoscopy.
Esophageal intramural pseudodiverticulosis is a rare condition characterized by the dilatation of submucosal glands. Based on approximately 250 cases reported to date, this condition is slightly more common in men than in women [1, 2]. Intramural pseudodiverticulosis is most commonly associated with gastrooesophageal reflux and esophagitis and less commonly with alcoholism, diabetes mellitus, Crohn's disease, tuberculosis, Mallory-Weiss syndrome and achalasia [3, 4]. The average age at presentation is 54 years and patients typically present with dysphagia, which is frequently associated with stricture formation, as in case we describe here [3, 4]. Symptoms usually respond well to anti-inflammatory medication and balloon dilatation of strictures.
Biphasic esophagography is generally recommended for the evaluation of an esophageal stricture. While a single contrast barium esophagogram provides maximal esophageal dilatation and is useful for the depiction of a stricture, a double contrast examination allows accurate imaging of the esophageal mucosa and wall. Barium esophagram is valuable for establishing this particular diagnosis as reports in the literature have suggested that the diverticular orifices are detected at endoscopy in only 20% of patients .
This case demonstrates the enduring usefulness of barium esophagography in the characterization of peculiar mucosal appearances at endoscopy.
Written informed consent was obtained from our patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
- VanLaer W, Urbain D, Reynaert H: Esophageal intramural pseudodiverticulosis. Clin Gastroenterol Hepatol. 2007, 5 (12): A22-10.1016/j.cgh.2007.10.015.View ArticleGoogle Scholar
- Herter B, Dittler HJ, Wuttge-Hannig A, Siewert JR: Intramural pseudodiverticulosis of the esophagus: a case series. Endoscopy. 1997, 29: 109-113. 10.1055/s-2007-1004084.View ArticlePubMedGoogle Scholar
- Flora KD, Gordon MD, Lieberman D, Schmidt W: Esophageal intramural pseudodiverticulosis. Dig Dis. 1997, 15: 113-119. 10.1159/000171591.View ArticlePubMedGoogle Scholar
- Bhattacharya S, Mahmud S, McGlinchey I, Schmidt W: Intramural pseudodiverticulosis of esophagus. Surg Endosc. 2002, 16: 714-715. 10.1007/s00464-001-4234-6.View ArticlePubMedGoogle Scholar
- Luedtke P, Levine MS, Rubesin SE, Weinstein DS, Laufer I: Radiologic diagnosis of benign esophageal strictures: a pattern approach. Radiographics. 2003, 23 (4): 897-909. 10.1148/rg.234025717.View ArticlePubMedGoogle Scholar
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.