- Case report
- Open Access
- Open Peer Review
Allergic hemiglossitis as a unique case of food allergy: a case report
© Aziz and Dioszeghy; licensee BioMed Central Ltd. 2008
- Received: 23 September 2007
- Accepted: 06 March 2008
- Published: 06 March 2008
A unique case of topical food allergy is presented with unilateral swelling of the tongue with ulceration. Only one similar case has been reported in 1972.
76 years old female patient presented at the Emergency Department with a unilateral painful swelling and ulcerations of the tongue after eating mint chocolate. However the swelling did not compromised the airways the presentation was rather frightening for the patient. The allergic reaction responded to the parenteral steroid and oral chlorphenamine treatment and the three month follow up only revealed minimal scar formations.
Unilateral hemiglossitis is a rare form of allergic reactions which is usually self-limiting with full recovery of which takes an unusually long time.
- Allergic Reaction
- Food Allergy
- Tongue Movement
- Minimal Scar
Allergic reactions often cause swelling in the tongue, which is usually more frightening than dangerous. Hypersensitivity to specific food or medications is believed to be the most common cause [1–3]. However, the airway might become compromised and life-threatening manifestations have also been reported ; therefore, these patients are relatively aggressively treated and observed for as long as necessary. These allergic reactions are usually more diffuse, often with swelling of the glottis and are presented along with other systemic symptoms.
Localised swelling of only one side of the tongue was described by Chavanne as allergic hemiglossitis in 1972, and was related to alimental allergic reaction . He also noted that the swelling was accompanied by the development of ulcers and the recovery took several months.
A 76-year-old otherwise fit and healthy female presented at the Accident and Emergency Department at 2:15 am with the complaint of a mildly painful and remarkably swollen tongue that developed after eating mint chocolate. Although the patient had tenderness and the frightening swelling in the mouth causing discomfort and moderate difficulty in swallowing, she had no shortness of breath or any other complaint. She gave a medical history of rheumatic polimyalgia in the past requiring no medical treatment at present. She remembered a previous allergic reaction to mint.
There was no skin rash or any other systemic reaction, and the vital parameters were stable. Blood results showed a mild elevation of C-reactive protein (CRP = 17) and erythrocyte sedimentation rate (ESR = 33).
As the symptoms were considered as a local allergic reaction, the patient was given 4 mg chlorphenamine orally and 100 mg hydrocortisone injection intramuscularly. The swelling responded to the medication quickly and the patient was discharged after a period of observation.
The presented case is a rare, usually benign, but quite frightening manifestation of a food allergy which is typically a Type I allergic reaction developing within seconds or minutes after contact with the allergen. Our patient had a similar initial presentation to the only other known case reported in  and had a similarly slow resolution.
However, allergic glossitis is described as a self-limiting condition with a full recovery; the hemiglossitis form we have presented proved to be slower healing with some scarring still visible after three months. Nevertheless, this caused no complaint for the patient. Clinicians should be aware of this in order to give reassuring information to their patients.
Allergic hemiglossitis is a unique form of localised allergic reaction most likely caused by food. The swelling responds promptly to anti-allergic medication but the ulceration takes longer to heal. Recovery may take up to three months.
Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
- Martínez Alonso, Melgosa Callejo, Fuentes Gonzalo, Martín García: Fixed drug eruption on the tongue due to clarithromycin. s.l.: Contact Derm. 2005, 53 (2): 121-2. 10.1111/j.0105-1873.2005.0650h.x.Google Scholar
- Kamata Y, Iwamoto M, Kamimura T, Kanashiki E, Yoshio T, Okazaki H, Morita T, Minota S: Repeated massive tongue swelling due to the combined use of estramustine phosphate and angiotensin-converting enzyme inhibitor. s.l.: J Investig Allergol Clin Immunol. 2006, 16 (6): 388-90.Google Scholar
- Flaitz CM, Chavarria C: Painful tongue lesions associated with a food allergy. s.l.: Pediatr Dent. 2001, 23 (6): 506-7.Google Scholar
- Hussein Gadban, Peter Gilbey, Yoav Talmon, Alvin Samet: Acute edema of the tongue: a life-threatening condition. s.l.: Ann Otol Rhinol Laryngol. 2003, 112 (7): 651-3.Google Scholar
- Chavanne L: (Case of allergic hemiglossitis). s.l.: JFORL J Fr Otorhinolaryngol Audiophonol Chir Maxillofac. 1972, 21 (1): 71-Google Scholar
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.