Fig. 1

This figure depicts an algorithm that can be used in patients with fever, bycitopenia or pancytopenia, and hepatomegaly and/or splenomegaly. * Exclude Visceral Leishmaniasis, Epstein-Barr Virus, Human immunodeficiency Virus, Cytomegalovirus, Malaria, Shcistosomiasis, Histoplasmosis, Mycobacteria, Typhoid Fever, Brucellosis, Tuberculosis, Parvovirus B19, Influenza, Rubella, Parainfluenza, Hepatitis A, Adenovirus. ** Exclude Leukemia, Polycetemia Vera, Lymphoma, Myelofibrosis with Myeloid Metaplasia via bone marrow, lymph node or spleen biopsy, respectively. *** Exclude Splenic Tumors, Sarcoidosis, Gaucher’s Disease via Splenic, lymph node or bone marrow biopsy, respectively; We would also recommend testing levels of Anti-Nuclear Antibodies, not to miss out on Systemic Lupus Erythematous; Do not overlook the possibility of Systemic Juvenile Idiopathic Arthritis. **** Exclude Autoimmune Anemia and Hemoglobinopathies via direct agglutination and hemoglobin analysis/DNA tests, respectively; Explore the possibility of vitamin deficiencies