Table 1 Characteristics of the antibodies [45]
E-Selectin/CD62E/SELE (D-7): sc-137054 | E-Selectin Antibody (D-7) is an IgG2a κ mouse monoclonal E-Selectin antibody (also designated Selectin E antibody, or CD62E antibody) that detects the E-Selectin protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. E-Selectin (also designated ELMA-1 or CD62E) is expressed on endothelial cells, exhibit overlapping ligand specificities. E-Selectin is expressed by cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining |
P-Selectin/CD62P/SELP (CTB201): sc-8419 | P-Selectin Antibody (CTB201) is an IgG1 κ mouse monoclonal P-Selectin antibody (also designated CD62 antibody, SELP antibody, selectin P antibody) that detects the P-Selectin protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM. Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells. It is also recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes |
HIF-1 α AB: sc-53546 | HIF-1α Antibody (H1α 67) is an IgG2b κ mouse monoclonal HIF-1α antibody that detects HIF-1α of mouse, rat and human origin by WB, IP, IF and IHC(P). Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors (including HIF-1α) induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. In response to hypoxia, HIF-1α is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex |