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Table 1 Review of research on the frequency, distribution, and therapy of mediastinal liposarcoma

From: Mediastinal liposarcoma: a case report and review of the literature

Authors

Reported year

Age (years)/sex

Location of mass

Symptom

Size(cm)

Histologic analysis

Treatment

Follow up

Hirano

2014

53/F

Anterior

Chest discomfort

31 × 18 × 12

Well-differentiated liposarcoma

Surgical resection

No rec after 7 months

Fukuhara

2014

77/M

Anterior

Dyspnea of exertion

36 × 20 × 6.5

Well-differentiated liposarcoma

Surgical resection

No recurrence on 2 years

Luna-Martínez

2014

53/F

Anterior

Chest pain, cough and dyspnea of exertion

9 × 9

Pleomorphic liposarcoma

Surgical resection and radiotherapy (adjuvant)

Rec. after 16 years

Weissferdt

2014

52/F

Anterior

Dyspnea

35

Well differentiated liposarcoma

Surgical resection

Died due to the recurrence after 60 months

68/F

Anterior

Dyspnea

13

Well differentiated liposarcoma

 

No rec. on 16 months

57/M

Anterior

Dyspnea

10

Thymolipoma

 

No rec. on 36 months

Arrarás-Martínez

2015

68/M

Posterior

Dyspnea, dysphagia, palpitation

17.5 × 13x14

Mixed liposarcoma

Surgical resectionand chemotherapy(adjuvant)

Rec. after 1 year and died 3 months later

Mani

2015

28/F

Anterior

Asymptomatic

28.0 × 19.0 × 8.0

Well-differentiated liposarcoma

Surgical resection

No rec. (dates N/A)

Khan

2016

43/M

Anterior

Dyspnea and chest pain

4.8 × 12.6

Myxoid liposarcoma

Surgical resection and radiotherapy (adjuvant) and chemotherapy(adjuvant)

No recurrence on 10 months of follow up

Hamanaka

2016

74/M

Posterior

Dry cough

11 × 8 × 7

Dedifferentiated liposarcoma

Surgical resection

No rec. on 8 months

Zhao

2016

63/M

Posterior

Chest pain and dyspnea

24 × 22 × 16

Well-defferentiated liposarcoma

Surgical resection

1st:after 12 months:surgery

2nd:after 2 yrs-died after 3 months

Muthukumar

2016

45/M

Posterior

Cough and dyspnea

14.5 × 13.5x6.5

Dedifferentiated myxoid liposarcoma

Surgical resection-radiotherapy (Adjuvent)

N/A

Mansuet-Lupo

2017

63/M

Anterior

Asymptomatic

N/A

Dedifferentiated liposarcoma

Surgical resection

N/A

Huang

2017

57 /M

Anterior

Dyspnea

27 × 20 × 15

Well-differentiated liposarcoma

Surgical resection

N/A

Weaver

2017

73/M

Posterior

Asymptomatic

12 × 10 × 6

30.5 × 16.5 × 8.5

Dedifferentiated liposarcoma

Surgical resection and chemo (neoadjuvant)

No rec. after 4 months

Miura

2018

45/F

Middle

Asymptomatic

12.7

Dedifferentiated liposarcoma

Surgical resection

After 12yrs:surgery

No rec

After 12 months

62/F

Middle

Asymptomatic

12

Dedifferentiated liposarcoma

Surgical resection

After 28 months:radiation

No rec. After 17 months

81/M

Anterior

Asymptomatic

6.6 × 3

Dedifferentiated liposarcoma

Surgical resection

After 28 months:Surgery

After 8 months:Radiation

75/M

Posterior

Asymptomatic

20

Dedifferentiated liposarcoma

Surgical resection

No rec. After 3 months

78/M

Middle and posterior

Dyspnea and hoarseness

11

Dedifferentiated liposarcoma

Radiation

Died two weeks later

Yang

2018

63/M

Anterior

Dyspnea and cough

22 × 16.0 × 11

Mixed: well and dedifferentiated liposarcoma

Surgical resection

No rec. after 2 yrs

Furlan

2020

33/F

Anterior

Chronic cough

18.5 × 15.0 × 6.0

Well differentiated liposarcoma

Surgical resection

No rec. on 1 year

Liu

2021

34/F

Anterior

Chest pain and shortness of breath

4 operations due to repeated recurrence:

1- N/A

2- 1.5 × 3 × 4

3- 10 × 9 × 3

4- 13 × 7 × 4

1-N/A

2- Partly myxoid and partly dedifferentiated liposarcoma

3- Myxoid liposarcoma

4- Well differentiated liposarcoma

1- Neoadjuvant radiotherapy and surgical resection

2- Surgical resection

3- Surgical resection

4- Surgical resection

1-First rec. after 10 years,

2- Second rec. after 20 years,

3-Third rec. after 3 months,

No rec. on 2 years

Wong (6cases)

2022

76/F

Anterior

Dyspnea

10.5

Well-differentiated liposarcoma

Neoadjuvant radiotherapy and surgical resection

No recurrence on 2 years of follow up

48/M

Anterior and Posterior

Chest congestion

40

Well-differentiated liposarcoma

Surgical resection

No recurrence on 4 years of follow up

57/M

Anterior

Asymptomatic

10

Well-differentiated or dedifferentiated liposarcoma with myxoid features

Neoadjuvant radiotherapy and Surgical resection

No recurrence on 2 years of follow up

68/M

Anterior

Dyspnea

29

Well-differentiated or dedifferentiated liposarcoma with myxoid features

Surgical resection and adjuvant radiotherapy

No recurrence on 1 year of follow up

68/F

Anterior

Asymptomatic

9

Well-differentiated liposarcoma

Surgical resection

No recurrence on 1 year of follow up

44/F

Posterior

Dysphagia

2.5

Dedifferentiated liposarcoma

Surgical resection and adjuvant radiotherapy

No recurrence on 7 years of follow up

Current case

2023

52/M

Posterior

Dyspnea and cough

25 × 10×8

Well-differentiated liposarcoma

Surgical resection

No recurrence on 3 months of follow up