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Table 4 Comparisons of laboratory findings in reviewed patients

From: Wolman disease presenting with hemophagocytic lymphohistiocytosis syndrome and a novel LIPA gene variant: a case report and review of the literature 

Author

Ferritin ng/ml

Coagulopathy

Hb (g/l)

platelet (× 109/l)

WBC (× 106/l)

Neutrophil (× 106/l)

Bili T (mg/dl)

Bili D (mg/dl)

AST (U/l)

ALT (U/l)

LDH (U/l)

Albumin (g/dl)

Fibrinogen (mg/dl)

TG (mg/dl)

BM Hemophagocytosis

Perry et al. [11]

Low

 

Elevated

Elevated

Elevated

Yes

 

Low

 

Elevated

Elevated

Elevated

Yes

 

 

Elevated

Elevated

Santos et al. [4]

19,867

 

6.3

318,000

6120

Elevated

Elevated

299

68

3140

2.9

2.5

785

Yes

 

21,577

Yes

8.4

117,000

8500

Elevated

Elevated

540

130

3300

1.9

3.18

539

Yes

Taurisano et al. [3]

8900

Yes

7.1

53,000

19.58

17.32

258

114

2302

2.4

1.24

450

Yes

Yavas et al. [13]

 > 1650

7.6

92,000

12,000

361

Yes

Elsayed et al. [14]

2363

5

98,000

3800

1612

528

Yes

 

1664

6.9

95,000

5600

78

17

1612

2.2

1.5

No

 

2543

7.8

80,000

10,500

  

2

947

not done

Tinsa et al. [15]

4876

Yes

7.7

51,000

10,200

17

_

120

190

1107

1.8

308

Yes

Rabah et al. [16]

5600

Yes

6.9

73,000

11,900

19

13

 

38

3290

1.8

1.24

1594

Yes

Alabbas et al. [17]

22,683

Yes

6.6

39,000

4600

3200

19

9

670

229

3

1.6

Yes

Present case

5370

Yes

7.6

656,000

820

10

7.2

5.8

2930

603

2690

2.9

1110

  1. Hb hemoglobin concentration, WBC white blood cell count, Bili T bilirubin total, Bili D bilirubin direct, AST aspartate transaminase level, ALT alanine transaminase level, TG triglyceride level, BM bone marrow