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Table 1 The timeline of this case

From: Whole-blood ribonucleic acid sequencing analysis in methemoglobinemia: a case report

Time, day

Event

X

The patient took in a few breaths of orange–brown smoke

X + a few minutes

The patient became unwell, with dyspnea and numbness in his extremities

X + 2 hours 30 minutes

The patient was suffering from whole-body cyanosis

SpO2: 80–85% (15 L/minutes of oxygen), respiratory rate: 18/minute

MetHb level in arterial blood gas testing: 23.1%

X + 4 hours 30 minutes

The patient was transported to our center

His whole-body cyanosis had improved, and his subjective symptoms had disappeared

SpO2: 90% (15 L/minutes of oxygen), respiratory rate: 18/minute

MetHb level in arterial blood gas testing: 12.5%

Whole-blood RNA samples were collected

X + 4 hours 40 minutes

Methylene blue (100 mg) was administered intravenously

X + 4 hours 50 minutes

MetHb level in arterial blood gas testing: 6.0%

X + 5 hours

MetHb level in arterial blood gas testing: 1.8%

SpO2: 100% (5 L/minutes of oxygen)

Chest X-ray and chest CT showed no abnormal findings

X + 2 days

Whole-blood RNA samples were collected

X + 4 days

Whole-blood RNA samples were collected

He was discharged

X + 1 month

Chest CT and respiratory function tests showed no abnormal findings

X + 2 months

Chest CT and respiratory function tests showed no abnormal findings

X + 3 months

Chest CT and respiratory function tests showed no abnormal findings

  1. MetHb methemoglobin, CT computed tomography