Table 1 Characteristics of the cases
Characteristic | Case 1 | Case 2 | |
|---|---|---|---|
Age (months) | 9 | 6 | |
Gender | Male | Female | |
Presentation | Poor feeding, failure to gain weight, vomiting, constipation, bone deformities, restriction of joints movement, and hypercalcemia | Irritability on handling and hypercalcemia | |
Progression T0 | Ca (mg/dl) | 18 | 14.7 |
PO4 (mg/dl) | 4.2 | ||
ALP(U/l) | 93 | 152 | |
PTH (pg/ml) | 69.1 (10–65) | 20 (3.6–32) | |
Urinary calcium | 0.39 | ||
T1 | Ca (mg/dl) | 10.3 | 9.9 |
PO4 (mg/dl) | 2.5 | 3.8 | |
Vitamin D | 8.61 | ||
PTH (pg/ml) | 166 (15–65) | ||
Urinary calcium | 0.062 (up to 0.6) | ||
T2 | Ca (mg/dl) | 8 | |
T3 | Ca (mg/dl) | 10 | |
PO4 (mg/dl) | 3.8 | ||
PTH (pg/ml) | 19.79 (3.6–32) | ||
25 OH Vitamin D (ng/ml) | 15 (30–100) | ||
1,25 OH Vitamin D (ng/ml) | 78 pg/ml (20–54) | ||
Outcome | Death | Maintained normal calcium | |