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Table 3 Pertinent investigations at presentation including gammopathy workup

From: Amyloidosis: a case series and review of the literature

Pertinent investigations

Value (normal range)

WBC

5.5 × 109/L (3.5–10.5)

ANC

3.8 × 109/L (2.0–7.5)

Hemoglobin

112 g/L (115–155)

MCV

102 fL (80–100)

Platelets

Creatinine

261 × 103/L (150–450)

eGFR

46 (> 90)

Ionized calcium

1.68 mmol/L (1.12–1.3)

PTH

0.3 pg/mL (1.2–8.4)

Gammopathy workup

 IgG

29 g/L (7–15)

 IgM

 < 0.2 g/L (0.46–3.04)

 IgA

 < 0.31 g/L (0.92–4.53)

 Beta-2 microglobulin

603.9 mg/L (67.8–198.3)

24-hour urine protein

5.36 g (< 0.2) with 99% gamma globulins

 Urine protein electrophoresis

IgG kappa and free kappa

 Serum protein electrophoresis

 Serum immunofixation

Monoclonal protein 20 g/L

IgG kappa

 Serum free light chains

Lambda: 3.8 mg/L (5.7–26.3)

Kappa: 3620 mg/L (3.3–19.4)

Kappa/lambda ratio: 952

  1. WBC White Blood Cells, ANC Absolute Neutrophil Count, MCV Mean Corpuscular Volume, PTH Parathyroid Hormone