High-grade large cell neuroendocrine carcinoma of the esophagus: a case report and review of the literature

Table 1 Review of all cases of poorly differentiated, large cell esophageal neuroendocrine carcinoma

Patient	Age	Gender	Smoking	Location	Stage	Presentation	Treatment	Survival (months)
1 [6]	83	M	N/A	Upper	IVA	Dysphagia	Palliative	< 2
2 [7]	58	M	N/A	Lower	IIB	Dysphagia	Adjuvant cisplatin + etoposide	> 36
3 [8]	73	M	Current	Lower	IVB	Dysphagia	Adjuvant docetaxel + fluorouracil	20
4 [9]	51	M	Never	Lower	IA	Dysphagia	Adjuvant chemoradiotherapy	N/A
5 [10]	55	M	N/A	Lower	IVB	Abdominal pain	Palliative	1
6 [11]	81	M	N/A	Lower		Weight loss	Surgery	> 18
7 [12]	66	F	Never	Mid	IVB	Dysphagia	N/A	N/A
8 [13]	81	M	N/A	Mid		Dysphagia	Adjuvant chemoradiation	8
9 [14]	75	F	N/A	Lower	IIA	N/A	Adjuvant irinotecan + cisplatin + radiotherapy	13
10 [14]	60	M	N/A	Mid-lower	IIIB	N/A	Adjuvant irinotecan + cisplatin	13
11 [14]	69	M	N/A	Lower	IIIB	N/A	Neoadjuvant irinotecan + cisplatin + radiotherapy	18
12 [15]	43	M	Never	Lower	IVB	Abdominal pain	Fluorouracil + cisplatin	11
13 [16]	85	F	Second-hand smoking	Mid	IVA	Dysphagia	Palliative	1
14 [17]	65	M	N/A	Lower	IVA	Heartburn	Adjuvant chemotherapy	9

ISSN: 1752-1947