Fig. 2

Liver. a Gross appearance of liver at autopsy stage. The liver weighed 5100 g. b Multiple milky-colored solid nodules with a capsular appearance, the largest of which measured 80 mm, could be observed on the cut-surface of the liver. c Histological appearance of liver tumors at autopsy stage. High magnification image (window) showed tumor cells arranged in trabeculae and rosettes, with a high level of necrosis. d Histological appearance of liver tumors biopsied in February 2019 for comparison. e Ki-67 labeling index of liver tumor at autopsy stage was 4%. f Ki-67 labeling index of liver tumor biopsied in February 2019 was 10.1%. g Elastica–Masson staining of normal liver tissue at autopsy stage, showing narrowing of hepatic cell cords. h Silver staining of normal liver tissue at autopsy stage, showing collapsing of hepatic cells, indicating chronic congestion