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Table 1 Real-time polymerase chain reaction evaluation of periodontal pathogenic load at the first visit

From: Periodontal therapy for localized severe periodontitis in a patient receiving fixed orthodontic treatment: a case report

Bacteria

Pathogenic load

Pathogenic threshold

Status

Maxillary left second molar

Porphyromonas gingivalis

0.0E+00

1.0E+05

−

Tannerella forsythia

3.2E+03

1.0E+05

+

Treponema denticola

3.3E+05

1.0E+05

++

Prevotella intermedia

1.1E+06

1.0E+05

+++

Parvimonas micra

9.2E+03

1.0E+06

+

Fusobacterium nucleatum

7.6E+05

1.0E+07

+

Campylobacter rectus

4.1E+05

1.0E+06

+

Eikenella corrodens

2.4E+06

1.0E+07

+

Mandibular right second molar

Porphyromonas gingivalis

0.0E+00

1.0E+05

−

Tannerella forsythia

5.3E+06

1.0E+05

+++

Treponema denticola

4.5E+06

1.0E+05

+++

Prevotella intermedia

9.3E+06

1.0E+05

+++

Parvimonas micra

7.9E+06

1.0E+06

++

Fusobacterium nucleatum

1.0E+06

1.0E+07

+

Campylobacter rectus

1.2E+07

1.0E+06

+++

Eikenella corrodens

8.2E+06

1.0E+07

+

Saliva

Porphyromonas gingivalis

0.0E+00

1.0E+05

−

Tannerella forsythia

3.8E+06

1.0E+05

+++

Treponema denticola

6.1E+06

1.0E+05

+++

Prevotella intermedia

0.0E+00

1.0E+05

-

Parvimonas micra

1.3E+08

1.0E+06

+++

Fusobacterium nucleatum

5.7E+08

1.0E+07

+++

Campylobacter rectus

3.4E+08

1.0E+06

+++

Eikenella corrodens

1.2E+09

1.0E+07

+++

  1. The counts of several bacteria are > ten times the pathogenic load threshold. The pathogenic load is the quantity of detected bacteria in a sample. The pathogenic threshold represents a specific microbiological pathogenic load above which antibiotic therapy is recommended to reduce the risk of tooth or implant attachment loss (periodontal disease or peri-implantitis). Status refers to the levels of microbiological pathogenic load: − absent; + moderate and less than the pathogenic load threshold; ++ high and more than the pathogenic load threshold and associated with aggressive forms of disease; +++ very high (> ten times the pathogenic load threshold) and strongly associated with aggressive forms of disease and loss of bone attachment