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Table 2 The literature on cases of GBS with Brucella infection in childhood

From: The association between acute brucellosis with a Guillain–Barré syndrome-like presentation: a case report

Author/date

The patient

Manifestation

Diagnosis

Treatment

Al Essa Ya 1996

14-year-old girl with GBS associated with Brucella infection

Acute progressive ascending symmetric weakness, protracted paroxysms of severe hypertension

Coombs Wright titration

Nerve conduction studies

Rifampicin + doxycycline

Plasma exchange sessions

Partial recovery after 2 months

Namiduru 2003

14-year-old girl with GBS associated with brucellosis

Acute progressive ascending symmetric weakness

CSF culture for Brucella

Wright agglutination test

Nerve conduction studies

Rifampicin + cotrimoxazole

Plasma exchange sessions

Barzegar 2009

9-year-old boy with GBS associated with brucellosis

Progressive weakness in the lower extremities paresthesia

Wright agglutination test

Mercaptoethanol titer negative

Nerve conduction studies

Plasmapheresis in four sessions every other day

Onur Balci 2013

11-year-old female with brucellosis diagnosed with GBS

Fever, pain while walking, pain on knees and elbows, pain, and numbness on hips and legs for 3 weeks

Brucella agglutination

Test

Brucella IgG was positive

Positive blood culture

Nerve conduction studies

Rifampicin + streptomycin + doxycycline

Intravenous immunoglobulin for 5 days

  1. This case demonstrates a rare case of brucellosis neurologic manifestation. Brucellosis should be kept in mind in all patients with acute paralysis and GBS-like signs, especially in those who live in endemic areas