Table 1 Liver tests of patient
| Â | Alkaline Phosphatase (U/L) | Total Bilirubin (mg/dL) | Alanine Aminotransferase (U/L) | Aspartate Aminotransferase (U/L) | Comments |
|---|---|---|---|---|---|
Baseline liver tests | 82 | 0.7 | 21 | 26 | Start mifepristone 300Â mg daily |
Week 7 | 187 | 0.6 | 15 | 26 | Â |
Week 8 | Â | Â | Â | Â | Increase mifepristone 300Â mg bid |
Week 13 | 147 | 11.3 | 73 | 68 | Mifepristone discontinued |
Week 14 | 178 | 23.0 | 46 | 76 | Start Ursodiol 300Â mg daily |
Week 15 | 234 | 28.3 | 38 | 76 | Peak bilirubin |
Week 19 | 299 | 7.1 | 192 | 172 | Peak alkaline phosphatase and aminotransferase activities |
Week 21 | 233 | 3.6 | 142 | 103 | Â |
Week 25 | 124 | 1.2 | 71 | 52 | Â |
Week 35 | 105 | 0.5 | 36 | 36 | Â |
Week 40 | 84 | 0.4 | 30 | 36 | Complete resolution |