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Table 1 Laboratory test results 6 months before and during the first 91 days after the infusion of zoledronic acid

From: Lessons learned from long-term side effects after zoledronic acid infusion following denosumab treatment: a case report and review of the literature

Laboratory test

Reference

15 December 2020

29 April 2021

Day 7

Day 11

Day 54

Day 91

Hemoglobin (g/L)

117–155

130

133

132

  

136

Leukocyte (E9/L)

3.4–8.2

5.2

6.1

8.0

  

6.5

Thrombocyte (E9/L)

150–360

245

237

325

  

288

CRP (mg/L)

< 4

  

84

41

 

2

Calcium (mmol/L)

2.15–2.51

2.34

2.30

2.32

   

Calcium-ion (mmol/L/ph7.4)

1.16–1.3

  

1.23

   

Creatinine (μmol/L)

50–90

69

73

62

   

ALP (U/L)

35–105

44

 

73

  

41

Kalium (mmol/L)

3.3–4.9

  

3.9

  

4.1

Natrium (mmol/L)

137–145

  

139

  

142

SR (mm/h)

< 40

5

 

47

   

S-25OHD (nmol/L)

> 50

139

 

163

   

INR

2–3

2.3

2.2

1.7

2.1

2.1

2.2

PTH (ng/L)

12–47

46

 

45

  

TSH (mU/L)

0.3–4.2

1.55

 

10.56

6.30

1.73

T4-V (pmol/L)

11–22

18

 

16

21

20

ALT (U/L)

< 35

23

 

  

30

  1. CRP C-reactive protein, ALP alkaline phosphatase, SR sedimentation rate, S-25OHD serum 25-hydroxyvitamin D, INR international normalized ratio, PTH parathyroid hormone, TSH thyroid-stimulating hormone, T4-V free thyroxine, ALT alanine aminotransferase