Fig. 3
From: Bone metastatic carcinoma coexisting with plasma cell myeloma: a case report
A Hematoxylin and eosin (HE) ×20: Bone marrow trephine section showing diffuse infiltration with nests and islands of carcinomatous-like cells set in a fibrous stroma. B HE ×40: Large carcinomatous tumor cells with atypical and hyperchromatic nuclei. C Immunohistochemistry (IHC) ×20: The carcinomatous component shows diffuse positive staining for CK7. D IHC ×10: CD138 showing positive staining for sparse small plasma cells. The red arrow points to the positive staining of the carcinomatous cells for CD138. Black arrows point to the positive staining of the plasma cells for CD138