From: Systemic lupus erythematosus with trisomy X: a case report and review of the literature
Reported cases | Present case | |||||
---|---|---|---|---|---|---|
Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | ||
Year of report | 1987 | 1991 | 2016 | 2020 | 2021 | 2021 |
Age at onset of SLE (years) | 26 | 21 | 28 | 11 | 16 | 17 |
Ethnicity | Caucasian | Asian | Asian | African | Asian | Asian |
Clinical manifestations | ||||||
Hematologic disorder | Hemolytic anemia lymphopenia | Hemolytic anemia | Hemolytic anemia | Hemolytic anemia | Anemia pancytopenia | Hemolytic anemia pancytopenia |
Neurological disorder | ND | Epilepsy | (−) | (−) | (−) | (−) |
Renal disorder | ND | (+)MPGN | (−) | (+)NS | (+)No biopsy | (+)No biopsy |
Serositis | ND | ND | (−) | (−) | (−) | (+) |
Joint manifestations | Polyarthritis | ND | Arthritis | Arthritis | (−) | (−) |
Mucocutaneous manifestation | ND | ND | (−) | (−) | Malar erythema oral ulcer | (−) |
Laboratory index | ||||||
Antinuclear antibody | (+) | (+) | (+) | (+) | (+) | (+) |
Anti-DNA antibody | ND | (+) | (+) | (+) | (+) | (+) |
Anti-Sm antibody | ND | ND | (−) | ND | (+) | (+) |
Anti-SS-A/B antibody | (+) | ND | (+) | ND | (+) | (+) |
Anti-RNP antibody | (+) | ND | (+) | ND | (+) | (+) |
Low complement | (−) | (+) | (+) | (+) | (+) | (+) |