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Fig. 5 | Journal of Medical Case Reports

Fig. 5

From: Waardenburg syndrome type 4 coexisting with open-angle glaucoma: a case report

Fig. 5

AS-OCT of iris configuration and ultrasound biomicroscopy (UBM) of filter bleb in the right eye. a Open angle was seen. b Superior part of iris, showing atrophy of the pigmented anterior border layer (devoid of pigmentation or melanin pigment in the anterior border layer) resulting in a hyporeflective area of anterior surface and reduced light absorption. The OCT signal is therefore able to penetrate more deeply, which exaggerates the typical signal of the posterior pigmented epithelium. c, f Heterochromic iris in the nasal (c) and temporal part (f). Normal part of iris shows a clear hyperreflective signal of the anterior border layer, increasing light absorption and resulting in optical shadowing and decreased visualization of the posterior pigmented epithelium. In the part with a hyporeflective signal of the anterior border layer, reverse shadowing occurs with an obvious signal of the posterior pigmented epithelium. d Filter bleb in the right eye. e The inferior part of the iris is normal. AS-OCT shows a hyperreflective signal of the anterior border layer, while shadowing occurs with little signal from the posterior pigmented epithelium. g The part of the iris with hypopigmentation in the right eye, sparing sections between 3:30 and 8:30 o’clock and between 10:30 and 12:00 o’clock

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