Fig. 1From: A novel missense mutation in complement factor I predisposes patients to atypical hemolytic uremic syndrome: a case reportHE-stained biopsy (400×) reveals (A): glomeruli ischemia and shrinkage (left), and thickened wall of arterioles with occlusion lumen and “onion skin” appearance. B Another glomeruli shows endothelial swelling, capillary loop occlusion, and mild mesangial hyperplasia. Electron microscopy (C) shows expansion of subendothelial space with electrolucent materialBack to article page