Fig. 1.

Histological analysis for the renal biopsy specimens in case 1 under light microscope. A Hardened glomerulus [hematoxylin and eosin (HE) staining, ×200]. B Glomerular periballoon fibrosis [periodic acid–Schiff–methenamine (PASM) staining, ×200]. C Dilation of capillary loops and presence of thrombotic substances in the lumen [periodic acid–Schiff (PAS) staining, ×200]. D Polyhemoglobin deposition in the glomeruli (Masson staining, ×200). E Electron microscopy results showing capillary endothelial cells with obvious vacuolar degeneration and a large number of lipid vacuolar protein substances in the cavity (scale bar, 5 μm)