Table 2 The diagnostic criteria in our patient

Clinical

Lung: chest pain with hemoptoic sputum, bilateral nodular excavated lung lesions

Kidney: microscopic hematuria, positive urine sediment, 24-hour proteinuria

ENT: dysphonia, epistaxis, left ear deafness, subglottic stenosis on nasofibroscopy, perforation of the medial sinus wall

Ophthalmic: red eyes, bilateral episcleritis

Cardiovascular involvement: multiple thrombosis, circumferential pericardial effusion

Lumbar: lumbago, retroperitoneal fibrosis

Biology

Anticytoplasmic neutrophil antibodies ANCA-PR3 positive at 63 IU/mL

Histology

Biopsies not done because of the therapeutic emergency and the impossibility of stopping the anticoagulant treatment