From: Cerebral lesions in hematological malignancies: a case report
Differential diagnosis | Supportive | Conflicting |
---|---|---|
Ischemia | Subacute symptoms Brain CT showing single hypodense lesion. | No cerebrovascular territory Expanding lesion |
Lymphoma | A single area of altered signal History of hematological malignancy | No hematological disease activity Lymphoma subtype (follicular) Negative histologic sample |
Glioma Low grade High grade | A single area of altered signal Imaging (MRI) features Growing speed | No histological feedback Not typical spectroscopy Too fast growth Imaging (MRI) features |
Opportunistic infection Bacterial Fungal Viral | Hematological disease Immunomodulatory therapy Relatively frequent Relatively frequent Lumbar puncture positive for JC virus presence | No typical imaging aspect Less common Negative CSF microbiological test No typical imaging aspect Negative CSF microbiological test |