Fig. 2

Diagnostic imaging of the liver, bile ducts, and pancreas, and a liver biopsy. A A dynamic scintigraphy at 1 hour was performed, supplemented with static images after 3, 6, and 24 hours. After 6 hours the static image was supplemented with SPECT/low dose CT. It showed delayed uptake in the liver parenchyma, delayed clearance of the blood pool and the liver parenchyma, and delayed and sparse distribution of the gallbladder to the intestines. SPECT/low dose CT was performed after 6 hours to verify the sparse uptake in the intestines. B 18F-DOPA PET/CT with diffuse uptake of DOPA throughout the entire pancreas. Black arrows demonstrating the pancreas. C Hematoxylin and eosin stained slide of the liver biopsy revealed hepatocytic rosette formation and marked cholestasis with bile plugs. Blue arrow indicating a bile plug