Parameter | No. of points (criteria for scoring) |
---|---|
Known underlying immunosuppression | 0 (no) or 18 (yes) |
Temperature (°C) | 0 (< 38.4), 33 (38.4–39.4), or 49 (> 39.4) |
Organomegaly | 0 (no), 23 (hepatomegaly or splenomegaly), or 38 (hepatomegaly and splenomegaly) |
Number of cytopenias | 0 (one lineage), 24 (two lineages), or 34 (three lineages) |
Ferritin (ng/mL) | 0 (< 2000), 35 (2000–6000), or 50 (> 6000) |
Triglyceride (mmol/L) | 0 (< 1.5), 44 (1.5–4), or 64 (> 4) |
Fibrinogen (g/L) | 0 (> 2.5) or 30 (< 2.5) |
AST, U/L | 0 (< 30) or 19 (> 30) |
Hemophagocytosis features on bone marrow | 0 (no) or 35 (yes) |