Table 1 Peripheral blood characteristics at diagnosis and 3 months after vitamin B12 supplementation
From: Megaloblastic anemia-related iron overload and erythroid regulators: a case report
Biological parameters | Unit | At diagnosis | 3 months later | Laboratory reference range |
|---|---|---|---|---|
Hemoglobin | g/L | 57 | 129 | 129–170 |
Mean corpuscular volume | fL | 99 | 90 | 80–100 |
Reticulocytes | 109/L | 16 | 94 | NA |
Absolute neutrophil count | 109/L | 2.2 | 5.4 | 1.5–7.5 |
Platelets | 109/L | 89 | 240 | 150–400 |
Creatinine | µmol/L | 171 | 200 | 59–104 |
Estimated glomerular filtration rate (CKD-EPI formula) | mL/minute/1.73 m2 | 32 | 26 | NA |
Total bilirubin | µmol/L | 31 | 9 | 2–24 |
Indirect bilirubin | µmol/L | 20 | 5 | 2–17 |
Haptoglobin | g/L | 0.4 | 1.8 | 0.5–2.0 |
Lactate dehydrogenase | U/L | 910 | 164 | 135–225 |
Sideremia | µmol/L | 36 | 13 | 5.8–34.5 |
Ferritin | µg/L | 537 | 437 | 30–400 |
Transferrin | g/L | 1.60 | 2.10 | 2.0–3.6 |
Transferrin saturation coefficient | % | 88 | 25 | 25–40 |
Reactive C protein | mg/L | 1.2 | 0.9 | 0.3–5.0 |
Vitamin B9 | nmol/L | 21 | – | 8.8–60.8 |
Vitamin B12 | pmol/L | <111 | 743 | 145–569 |
Erythropoietin | mUI/mL | 43.9 | 8.6 | 2.6–18.5 |
GDF15 | pg/mL | > 8000 | 2,240 | 1080–3700* |
Erythroferrone | ng/mL | 14.44 | 0.53 | 0.01–1.92* |
Hepcidin† | nmol/L | 10.6 | 28.7 | 4–30 |