Fig. 4From: Graves’ disease coexisted with resistance to thyroid hormone: a case reportDirect sequencing analysis of TRβ gene in genomic DNA extracted from peripheral blood leukocytes. Sequence analysis revealed a heterozygous point mutation in exon 8, AGA to AGC, resulting in substitution of arginine by serine at codon 282 (R282S). The arrow indicates the site of the point mutationBack to article page