Effectiveness of convalescent plasma therapy in eight non-intubated coronavirus disease 2019 patients in Indonesia: a case series

Rahardjo, Theresia Monica; Yogipranata, Elizabeth; Naswan, Ardian Hediyanto; Sari, Fitri Rahayu; Budiono, Fajar; Permatasari, Hernawati; Chuntari, C. H. R. Driantik

doi:10.1186/s13256-021-03059-y

Journal of Medical Case Reports

Table 3 Comparison of parameters before and after Convalescent Plasma Therapy

From: Effectiveness of convalescent plasma therapy in eight non-intubated coronavirus disease 2019 patients in Indonesia: a case series

Parameter	CPT	Time	Patient 1	Patient 2	Patient 3	Patient 4	Patient 5	Patient 6	Patient 7	Patient 8
Respiration	Before		19–20	28	28–33	36	27–30	40	17–18	22–24
	After	Day 1	20–23	16–20	20–22	30	20–22	28	18–20	20–22
		Day 3	16	16–18	18–20	15–17	19–20	18–20	18–20	20–22
		Day 5	24	16–18	18–20	22–27	19–20	18–19	18–20	18–20
		Day 7	16–18	16–18	18–20	20–24	16–18	18–19	18–20	18–20
O₂ support	Before		NRM 12 L/minute	NRM 15 L/minute	NRM 15 L/minute	HFNC FiO₂ 70% flow 40 L/minute	NC 4 L/minute	NRM 15 L/minute	NC 3 L/minute	HFNC FiO₂ 95% flow 60 L/minute
	After	Day 1	NRM 15 L/minute	NRM 15 L/minute	NC 3 L/minute	HFNC FiO₂ 70% flow 40 L/minute	NC 4 L/minute	NRM 10 L/minute	NC 3 L/minute	HFNC FiO₂ 90% flow 60 L/minute
		Day 3	NRM 15 L/minute	NC 3 L/minute	NC 3 L/minute	HFNC FiO₂ 70% flow 50 L/minute	NC 4 L/minute	NC 4 L/minute	NC 3 L/minute	HFNC FiO₂ 50% flow 35 L/minute
		Day 5	NC 4 L/minute	Room air	NC 3 L/minute	HFNC FiO₂ 40% flow 35 L/minute	NC 3 L/minute	NC 4 L/minute	NC 3 L/minute	HFNC FiO₂ 35% flow 30 L/minute
		Day 7	NC 4 L/minute	Room air	Room air	NC 4 L/minute	Room air	Room air	NC 3 L/minute	NRM 15 L/minute
O₂ saturation	Before		96–97	94	97–98	90	94–96	90	95–98	90–93
	After	Day 1	94–96	97	97–98	95–99	96	90–94	97–98	96–99
		Day 3	98	98	98–99	97–98	93–97	96	99	97–98
		Day 5	97–98	98–99	98–99	95–98	97–98	97–98	99	97–98
		Day 7	99	98–99	98–99	95–97	98–99	98	99	97–98
Thorax imaging	Before		Bilateral infiltrate	Bilateral infiltrate	Bilateral infiltrate	No specific process	Bilateral infiltrate	–	Bilateral infiltrate	Bilateral infiltrate
	After	Day 1	–	–	–	Bilateral infiltrate	–	–	–	–
		Day 3	Infiltrate reduction	–	–	–	–	–	–	–
		Day 5	–	–	–	Infiltrate reduction	Bilateral infiltrate	–	Bilateral infiltrate	–
		Day 7	Infiltrate reduction	Infiltrate reduction	Infiltrate reduction	–	Infiltrate reduction	Paracardial infiltrate	Infiltrate reduction	Infiltrate reduction

CPT: Convalescent plasma therapy, NC: Nasal cannula, NRM: Non rebreathing mask, HFNC: High flow nasal cannula

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ISSN: 1752-1947

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