Fig. 4

The PET (a) and PET/CT (b) performed at the time of recurrence in September 2015 demonstrate a metabolically active subaortic lymph node metastasis (arrows). The subsequent PET (c), performed approximately 1 year after commencing treatment with pembrolizumab, did not demonstrated any metabolically active disease, and the PET/CT (d) confirms no metabolic activity is associated with the prior subaortic lymph node (arrow)