Table 1 Clinical description of coinfection cases and their outcomes

Admission date

14 June 2020

19 June 2020

Days of symptoms on admission

6

20

Admission diagnosis

Dengue fever

COVID-19

Day 1 hospitalization

Dengue IgM/NS1 positive (6 days of evolution)

rRT-PCR dengue positive

First chest X-ray clean

SARS CoV-2 rRT-PCR negative (20 days of evolution)

First chest X-ray: extensive interstitial infiltrates in both lung fields, blood culture negative

Day 2 hospitalization

SARS CoV-2 rRT-PCR positive (8 days of evolution)

Dengue IgM/IgG positive (22 days evolution)

RT-PCR dengue negative

Day 3 hospitalization

Second chest X-ray clean (9 days of evolution)

SARS CoV-2 rRT-PCR negative (23 days of evolution)

Culture orotracheal secretion positive for Staphylococcus aureus

Day 4 hospitalization

–

SARS CoV-2 rRT-PCR negative (24 days of evolution)

Day 5 hospitalization

–

IgG SARS-CoV-2 positive (24-day evolution)

Dengue IgM/IgG positive (24 days evolution)

Summary of clinical evolution and outcomes

The patient was kept under surveillance in the intensive care unit for having severe dengue criteria and coinfection with SARS CoV-2. She was discharged on the sixth day of hospitalization

She was followed up by phone. She has had adequate evolution and has remained without symptoms. The last follow-up was done in July 2020

The patient was admitted with a diagnosis of severe COVID-19 pneumonia and dengue fever with alarm signs. He remained in intensive care for 2 months, with progressive clinical deterioration worsened by the development of Klebsiella pneumoniae sepsis. He required prolonged ventilatory support until he finally died

Final diagnosis

Dengue/SARS CoV-2 coinfection

Dengue/SARS CoV-2 coinfection