Fig. 2
From: Primary hypothalamic lymphoma with clinical findings mimicking pituitary apoplexy: a case report
Microscopic image of diffuse large B-cell lymphoma. a Diffuse growth pattern with large cells with amphophilic cytoplasm, eccentric nuclei and one central nucleoli. Centroblasts with basophilic cytoplasm, vesicular chromatin and prominent nucleoli close to the nuclear membrane are also observed (hematoxylin and eosin, ×100). b Immunohistochemistry-positive neoplastic lymphoid cells for CD20 (×100). c Immunohistochemistry-positive neoplastic lymphoid cells for BCL6 (×100). d Ki67 immunohistochemistry indicated a high proliferative index of tumor cells, approaching 50% (×100)