Fig. 1

Schematic presentation of interventions, hemodynamics, catecholamine therapy, coagulation parameters and substituted clotting preparations over time. Interventions, hemodynamic data, laboratory results and all clotting preparations and blood products which were substituted or transfused during the course of treatment are shown. A representative catecholamine dosage is provided for each day of treatment. CPR cardiopulmonary resuscitation, V-V ECMO veno-venous extracorporeal membrane oxygenation, V-VA ECMO veno-venoarterial extracorporeal membrane oxygenation, MAP mean arterial pressure, bpm beats per minute, INR international normalized ratio of prothrombin time, PTT partial thromboplastin time, AT antithrombin concentration, Plt platelet concentration, TXA tranexamic acid, PCC prothrombin complex concentrate, IU international unit, FFP fresh-frozen plasma, pRBC packed red blood cells