Molecular remission after combination therapy with blinatumomab and ponatinib with relapsed/refractory Philadelphia chromosome-positive acute lymphocytic leukemia: two case reports

Table 1 Laboratory data

Peripheral blood	Case 1	Case2		Chemistry	Case 1	Case 2
White Blood Cell	6,100	14,300	/μl	Total Protein	7.2	7.6	g/dl
Neutrophil	79.3	80.7	%	Albumin	4.9	3.9	g/dl
Lymphpocyte	14.7	15.2	%	Uric Acid	6.6	5.4	mg/dl
Monocyte	5.6	3.1	%	Creatinine	1.02	0.75	mg/dl
Eosinophil	0.2	0.4	%	Total Bilirubin	0.2	0.2	mg/dl
Basophil	0.2	0.6	%	AST	19	21	IU/l
Red Blood Cell	409	472	×10⁴/μl	ALT	14	15	IU/l
Hemoglobin	12.6	13.5	g/dl	ALP	299	361	IU/l
Hematocrit	38.4	41.3	%	Bone marrow
MCV	93.9	87.5	fl	Cellularity	Normal	Normal
MCH	30.8	28.6	pg	Leukemia cells	8.2	0	%
MCHC	32.8	32.7	%	G-Banding	46,XY[20]	46,XX[20]
Platelet	29.2	13.5	×10⁴/μl	Minor BCR–ABL copy number	25,000	330	copies

MCV Mean Corpuscular Volume, MCH Mean Corpuscular Hemoglobin, MCHC Mean Corpuscular Hemoglobin Concentration, AST Aspartate Aminotransferase, ALT Alanine Aminotransferase, ALP Alkaline Phosphatase

ISSN: 1752-1947