Table 1 Benign skin and mammary lesions that often cause misinterpretation with mammary Paget’s disease
From: Advanced lesions of synchronous bilateral mammary Paget’s disease: a case report
Differential diagnosis of mammary Paget’s disease | Clinical manifestations of mammary Paget’s disease and benign inflammatory skin lesions in the nipple | |
|---|---|---|
Paget’s disease | Benign inflammatory skin lesions in the nipple | |
Eczema | Not itchy or slight itchy and is non-responsive to treatment | Itchy |
Psoriasis | No vesicles or pustules | Vesicles and pustules |
Irritant contact dermatitis | Nipple retraction or deformation | No change in the nipple, limited in areolae lesions |
Mammary duct ectasia | Usually unilateral | Bilateral |
Drug eruption | Sometimes with palpable lump | No lump |
Toker cells | Older age | Younger age |
Nipple duct adenoma | Mammographic lesions/microcalcifications | Normal mammogram |