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Table 1 Cytogenetic analyses

From: Transformation of a low-grade follicular lymphoma into a composite lymphoma combining a high-grade B-cell lymphoma and a lymphoblastic neoplasm expressing Terminal deoxynucleotidyl Transferase: a case report

Time of disease Type of sample Karyotype designation (ISCN 2016) FISH Bcl2 (% of interphase cells) FISH Myc (% of interphase cells)
Diagnosis Lymph node 48,XY,+X,der(1)t(1;8)(q21;q14)),+i(1)(q10),t(14;18)(q32;q21), [11]/50,sl,+ 12,+ 21[6]/46,XY [3].ish der(1)t(1;8)(MYC+),8q24(MYCx2) Rearrangement (85%) Gain (84%)
Third progression Ascites 48,XY,+X,der(1)t(1;8)(q21;q24),+i(1)(q10),t(8;22)(q24;q11),t(14;18)(q32;q21) [9] Rearrangement (90%) Gain (90%) and rearrangement by t(8;22) (90%)
  1. FISH Fluorescence in situ hybridization
  2. t(8;22)(q24;q11) is associated with genomic instability and a poor prognosis