Time of disease | Type of sample | Karyotype designation (ISCN 2016) | FISH Bcl2 (% of interphase cells) | FISH Myc (% of interphase cells) |
---|---|---|---|---|
Diagnosis | Lymph node | 48,XY,+X,der(1)t(1;8)(q21;q14)),+i(1)(q10),t(14;18)(q32;q21), [11]/50,sl,+ 12,+ 21[6]/46,XY [3].ish der(1)t(1;8)(MYC+),8q24(MYCx2) | Rearrangement (85%) | Gain (84%) |
Third progression | Ascites | 48,XY,+X,der(1)t(1;8)(q21;q24),+i(1)(q10),t(8;22)(q24;q11),t(14;18)(q32;q21) [9] | Rearrangement (90%) | Gain (90%) and rearrangement by t(8;22) (90%) |