Composite Epstein-Barr virus-positive mucosa-associated lymphoid tissue lymphoma and Epstein-Barr virus-negative diffuse large B-cell lymphoma in the parotid salivary gland of a patient with Sjögren’s syndrome and rheumatoid arthritis: a case report

Table 1 Summary of previously reported cases of Epstein-Barr virus-positive mucosa-associated lymphoid tissue lymphoma in patients with autoimmune disease

Reference	Age (years)/sex	AD	Anatomic site	EBERs ISH	EBV PCR	LMP1	Treated with methotrexate
[17]	74/F	DM	Stomach	< 30% cells	NS	NS	No
[6]	NS	SS	PG	< 5% cells	+	–	NS
[6]	NS	SS	PG	–	+	–	NS
[18]	49/F	SS	Thymus, lung, mediastinal LN	+/−	NS	NS	No
[7]	63/F	RA + SS	Periparotid soft tissue	+	NS	–	Yes
[7]	54/F	RA + SS	PG	+	NS	–	Yes

−, a few scattered positive tumor cells; +, majority of the tumor cells were positive
Abbreviations: DM dermatomyositis, SS Sjögren’s syndrome, RA rheumatoid arthritis, PG parotid gland, LN lymph node, AD autoimmune disease, NS not specified, EBV Epstein-Barr virus, EBERs encoded small ribonucleic acids, ISH in situ hybridization, PCR polymerase chain reaction, LMP1 latent membrane protein 1

ISSN: 1752-1947