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Table 2 Clinical and pathologic features of sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid

From: Activating BRAF mutation in sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid gland: two case reports and review of the literature

Feature

Data

Age

26–89 years (median 57)

Gender

55 F/6 M

Tumor sizea

0.5–13 cm (4.5 cm); n = 49

Synchronous PTC

7/44 (16%)

Background of LT

42/44 (95%)

Extrathyroidal extension

28/52 (54%)

Lymph node metastases

20/50 (40%)

Distant metastases

8/54 (15%)

IHC:

 Cytokeratin

32/32 (100%)

 Carcinoembryonic antigen

16/21 (76%)

 Thyroglobulin

3/56 (5%)

 Mucin

7/7 (100%)

 p63

24/24 (100%)

 Thyroid transcription factor-1

9/19 (47%)

 Chromogranin

0/12 (0%)

 Calcitonin

0/41 (0%)

Outcome data

 Alive without disease

25/40 (63%)

 Alive with disease

6/40 (15%)

 Deceased

9/40 (23%)

  1. Abbreviations: F female, M male, LT lymphocytic thyroiditis, IHC immunohistochemistry, PTC papillary carcinoma of the thyroid
  2. aLargest dimension of tumor used