| | Number | Probability | P value |
|---|
Advanced age | 94 | 4.3% | 0.0064 |
Nullipara | 113 | 3.5% | 0.0322 |
Large cyst | 18 | 5.6% | 0.1964 |
Bilateral cysts | 70 | 4.3% | 0.3231 |
Surgical history | 81 | 2.5% | 0.1814 |
Enlargement | 70 | 5.7% | 0.0079 |
Total | 174 | 2.3% | |
- A multivariate analysis of 174 patients with DNGT was performed to examine the influence of six representative factors that could be collected before starting DNGT, as follows: (1) “advanced age,” defined as patients who started DNGT at 41 years of age or older; (2) nullipara; (3) “large cyst,” defined as patients whose cyst sizes were 8 cm or larger at the start of DNGT; (4) “surgical history,” defined as patients who underwent surgery for the OMA; (5) bilateral cysts; and (6) enlargement. The number of patients with each factor, the probability of MT, and the P values are shown. “Advanced age,” “nullipara,” and “enlargement” were identified as significant risk factors for MT. “Large cyst,” “bilateral cysts,” and “surgical history” were not significant risk factors
- Abbreviations: DNGT dienogest therapy, MT malignant transformation, OMA ovarian endometrioma
