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Table 1 Summary of investigations

From: Severe hypothyroidism presenting as reversible proteinuria: two case reports

 

Reference range

Case 1 – follow-up (months)

Case 2 – follow-up (months)

0

2

4

6

0

2

4

6

TSH

0.4–4.0 U/L

100

9.8

4.4

1.2

100

10.42

1.56

1.8

Free T4

7–19 ng/L

0.2

7.9

8.6

9.1

0.3

6.1

7.7

10.2

Creatinine

44–105 umol/L

167

157

112

88

126

118

104

93

eGFR

> 90 ml/minute

36

37.4

56.2

75.3

43.7

47.3

55.1

63

Blood urea

2.5–7.1 mmol/L

4.6

4.8

5

5.2

3.2

3.3

3.3

4

CK

22–198 U/L

4473

765

322

125

3980

534

221

189

UPCR

<  0.4 mg/mg

3.2

2.4

0.4

0.4

1.6

0.9

0.7

0.6

Cholesterol

<  200 mg/dL

622

417

221

197

478

332

225

172

Triglycerides

<  150 mg/dL

254

156

102

93

332

165

83

92

Hemoglobin

110–145 g/L

102

105

118

131

112

117

119

121

MCV

80–90 fL

102

99

96

92

97

95

92

89

HbA1c

< 6.0%

5.90%

   

5.20%

   
  1. CK creatinine kinase, eGFR estimated glomerular filtration rate, HbA1c glycated hemoglobin, MCV mean corpuscular volume, T4 thyroxine, TSH thyroid-stimulating hormone, UPCR urine protein to creatinine ratio